Developmental Research Program
发展研究计划
基本信息
- 批准号:10709235
- 负责人:
- 金额:$ 8.52万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-19 至 2028-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAllyAreaAwardBasic ScienceBudgetsCancer CenterClinicalClinical InvestigatorClinical ResearchCollaborationsDataDedicationsDepartment of DefenseDevelopmentDisciplineDiseaseEarly DiagnosisEarly treatmentFinancial SupportFoundationsFundingFunding MechanismsFutureGoalsHumanIncidenceInstitutionMalignant NeoplasmsMalignant neoplasm of ovaryManuscriptsMedical centerOvarianPeer ReviewPopulation ResearchPreventionProductivityProgram Research Project GrantsPublishingQuality of lifeResearchResearch PersonnelResearch Project GrantsResourcesRestScientistSpecimenTexasTranslational ResearchUniversity of Texas M D Anderson Cancer CenterWomanWorkanticancer researchcandidate identificationdesignimprovedinnovationmortalitynovelovarian cancer preventionpatient populationpeerprogramssupportive environmenttranslational potentialtranslational study
项目摘要
Developmental Research Program SUMMARY/ABSTRACT
The purpose of the Developmental Research Program (DRP) is to fund promising projects by investigators
whose current work may not focus exclusively on ovarian cancer, but who propose highly innovative
translational studies of ovarian cancer that could become full SPORE projects or compete successfully for
funding outside of the SPORE. The DRP provides a unique opportunity for making available significant financial
support, and for demonstrating active institutional support, through a program that is rapidly responsiveto new
ideas or initiatives. Moreover, this program is rooted in a spirit of collaboration promoted by the SPORE
investigators who have an extensive track record of bringing investigators from other disciplines into ovarian
cancer research. The strength of the DRP rests in its ability to make available financial support needed to
access all the critical expertise and resources within the entire SPORE. This will allow us to develop
collaborative, multi-investigator, multi-institutional research projects with the support of innovative, investigator-
initiated projects that have the potential to flourish into reliable and productive translational research projects
that make a path from basic and/or population research projects into research focused on human clinical
specimens/patient populations. Over the course of the past decade, the MD Anderson OvarianSPORE has
supported DRP projects from 22 investigators. Collectively, these investigators have published 470 peer-
reviewed manuscripts related to ovarian cancer. Thirteen of the recipients have received peer-reviewedfunding
in ovarian cancer as either PI, Co-PI or Co-Investigator. The investigators have received funding from three
R01s, three R21s, three CPRIT awards, two Department of Defense Awards and four OCRA awards. One
awardee in the most recently funded cycle just received support from both the Ovarian Cancer Research Alliance and
Foundation for Women’s Cancer. Additionally, three former awardees have participated in full SPORE projects
after completing a DRP project.
开发研究计划概要/摘要
发展研究计划(DRP)的目的是资助研究人员有前途的项目
他目前的工作可能并不完全集中在卵巢癌上,但他提出了高度创新的建议,
卵巢癌的转化研究,可以成为完整的孢子项目或竞争成功,
在孢子之外的资金。DRP提供了一个独特的机会,
支持,并展示积极的机构支持,通过一个计划,是迅速响应新的
想法或倡议。此外,该计划植根于SPORE倡导的合作精神
研究者有将其他学科的研究者引入卵巢癌的广泛记录,
癌症研究。难民救济和重建方案的优势在于它有能力提供必要的财政支助,
访问整个SPORE内的所有关键专业知识和资源。这将使我们能够发展
在创新研究者的支持下,开展协作式、多研究者、多机构研究项目-
启动的项目有可能发展成为可靠和富有成效的转化研究项目
这使得从基础和/或人口研究项目进入人类临床研究的道路
样本/患者人群。在过去的十年中,MD安德森卵巢孢子已经
支持来自22名调查员的DRP项目。这些研究人员共发表了470篇论文,
回顾了与卵巢癌相关的手稿。13名获奖者获得了同行评审的资金
作为PI、Co-PI或合作研究者。调查人员已收到三人的资助
R 01,三个R21,三个CPRIT奖,两个国防部奖和四个OCRA奖。一
最近资助周期的获奖者刚刚获得卵巢癌研究联盟和
妇女癌症基金会。此外,三名前获奖者参加了完整的SPORE项目
完成一个DRP项目后。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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ROBERT C BAST其他文献
ROBERT C BAST的其他文献
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{{ truncateString('ROBERT C BAST', 18)}}的其他基金
The SIK2 Inhibitor GRN-300 Enhances PARP Inhibitor Sensitivity and Cytotoxic T-Cell Function in Ovarian Cancer
SIK2 抑制剂 GRN-300 增强卵巢癌中 PARP 抑制剂的敏感性和细胞毒性 T 细胞功能
- 批准号:
10709229 - 财政年份:2023
- 资助金额:
$ 8.52万 - 项目类别:
The University of Texas MD Anderson Cancer Center SPORE in Ovarian Cancer
德克萨斯大学 MD 安德森癌症中心 SPORE 在卵巢癌中的应用
- 批准号:
10709227 - 财政年份:2023
- 资助金额:
$ 8.52万 - 项目类别:
DIRAS3 disrupts K-RAS clustering and signaling, enhancing autophagy and response to autophagy inhibition
DIRAS3 破坏 K-RAS 聚类和信号传导,增强自噬和对自噬抑制的反应
- 批准号:
10707965 - 财政年份:2022
- 资助金额:
$ 8.52万 - 项目类别:
Development of Novel Ovarian Cancer Biomarkers for Early Detection Algorithms
开发用于早期检测算法的新型卵巢癌生物标志物
- 批准号:
10410452 - 财政年份:2020
- 资助金额:
$ 8.52万 - 项目类别:
Development of Novel Ovarian Cancer Biomarkers for Early Detection Algorithms
开发用于早期检测算法的新型卵巢癌生物标志物
- 批准号:
10226017 - 财政年份:2020
- 资助金额:
$ 8.52万 - 项目类别:
Development of Novel Ovarian Cancer Biomarkers for Early Detection Algorithms
开发用于早期检测算法的新型卵巢癌生物标志物
- 批准号:
10670063 - 财政年份:2020
- 资助金额:
$ 8.52万 - 项目类别:
Development of Novel Ovarian Cancer Biomarkers for Early Detection Algorithms
开发用于早期检测算法的新型卵巢癌生物标志物
- 批准号:
9916297 - 财政年份:2020
- 资助金额:
$ 8.52万 - 项目类别:
Project 4: SIK2 PROVIDES A NOVEL TARGET FOR OVARIAN CANCER THERAPY IN COMBINATION WITH PACLITAXEL AND INHIBITORS OF PARP
项目 4:SIK2 结合紫杉醇和 PARP 抑制剂为卵巢癌治疗提供新靶点
- 批准号:
10005298 - 财政年份:2017
- 资助金额:
$ 8.52万 - 项目类别:
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