A FAIR Bridge2AI Center (FABRIC)

Bridge2AI：一个公平的AI桥接中心(Fabric)总体总结 我们建议开发一个公平的Bridge2AI中心(Fabric)来组织一个大型财团 将生成数据和工具以实现新型人工智能算法应用的机构 解决影响人类健康的生物医学或行为问题。我们中心的做法是 开发管理核心，与团队核心一起设计和管理 Bridge2AI联盟的结构组件，重点是团队科学和包容性。 四个核心的产品和活动均由各自领域的专家领导， 他们在美国国立卫生研究院资助的大型项目中有着广泛的合作记录，例如 BD2K、我们所有人等。管理和团队核心位于华盛顿大学 加州圣地亚哥。由范德比尔特大学领导的道德核心将监督所有道德、法律、 和社会影响(ELSI)，从数据中生成指导方针并评估数据的公平性 发电项目(DGP)和其他财团产品。以大学为主导的标准核心 将确保所有产品和活动都遵循交易会(可找到、可访问、 可互操作、可重复使用)原则，并按照商定的标准进行协调/标准化。 由布罗德研究所领导的工具优化核心将利用其开发大型- 扩展软件，为整个联盟构建一个平台，其中核心和DGPS可以 他们的产品可供其他研究人员使用。它还将优化各种被认为是 对Bridge2AI非常有用。技能和劳动力发展将发展和提供教育 为整个联盟提供材料和活动，并优化其他人开发的软件。一个 特别强调面料的包容性，因为我们的愿景是建立一种新型的协调中心 在没有单一控制点的情况下，在哪些事务中(例如，数据访问、数据使用) 一成不变地记录在一个易于查阅的分类账中，所有人都可以看到。面料是设计的 因此，核心和DGPS中的各种线程交织成一个耐用的、可持续的中心 Bridge2AI财团。

Bridge2AI: a FAIR AI BRIDGE Center (FABRIC) Overall Summary We propose to develop a FAIR Bridge2AI Center (FABRIC) to organize a large Consortium of institutions that will be generating data and tools to enable the application of novel AI algorithms to solve biomedical or behavioral problems affecting human health. Our center’s approach is to develop an Administrative Core that, together with a Teaming Core, designs and manages structural components of the Bridge2AI Consortium with a focus on team science and inclusion. The products and activities of each of four Cores are led by experts in their respective fields, and who have an extensive track record of working together in large NIH-funded initiatives, such as BD2K, All of Us, etc. The Administrative and Teaming Cores are based at the University of California San Diego. The Ethics Core, led by Vanderbilt University, will oversee all ethical, legal, and social implications (ELSI), generate guidelines and assess fairness in data from Data Generation Project (DGP) and other Consortium products. The Standards Core, led by University of Texas Health, will ensure that all products and activities follow the FAIR (findable, accessible, interoperable, reusable) principles and are harmonized/standardized to agreed upon standards. The Tool Optimization Core, led by the Broad Institute, will use its experience developing large- scale software to build a platform for the whole Consortium, where Cores and DGPs can have their products available for other researchers. It will also optimize various tools that are deemed useful for Bridge2AI. The Skills and Workforce Development will develop and deliver educational materials and activities for the whole consortium and optimize software developed by others. A special emphasis for FABRIC is inclusion, as our vision is for a novel type of Coordinating Center where there is no single point of control and in which transactions (e.g., data access, data use) are immutably recorded in an easy-to-access ledger that is viewable by all. FABRIC is designed so that various threads in Cores and DGPs are interwoven into a durable, sustainable center for the Bridge2AI Consortium.