GENE THERAPY RESOURCE PROGRAM (GTRP): TASK AREA B FOR PRECLINICAL VECTOR CORE LABORATORY SCIENTIFIC ACTIVITIES

基因治疗资源计划 (GTRP)：临床前载体核心实验室科学活动的任务领域 B

• 批准号: 10725221
• 负责人: JULIE JOHNSTON
• 金额: $ 79.61万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10725221
• 关键词: Adenovirus Vector; Area; Biodistribution; Biological; Biological Assay; CRISPR/Cas technology; Capsid; Cells; Codon Nucleotides; Consultations; DNA; DNA cassette; Dependovirus; Detection; Endotoxins; Gene Silencing; Genes; Genome; Glycoproteins; Immunology; Induced Mutation; Laboratories; Lentivirus Vector; MicroRNAs; Mycoplasma; National Heart, Lung, and Blood Institute; Neutralizing antibody assay; Non-Viral Vector; Proteins; Quality Control; Regulation; Research Personnel; Resources; Retroviridae; Sequence Analysis; Serotyping; Services; Small Interfering RNA; Sterility; Structure; System; T cell response; Testing; Transcript; Transgenes; Viral; Virus; animal tissue; design; design and construction; detection assay; enzyme linked immunospot assay; gene therapy; good laboratory practice; in vivo; interest; neutralizing antibody; next generation sequencing; overexpression; particle; pre-clinical; programs; testing services; therapeutic gene; vector; vector biodistribution; vector genome

The Preclinical Vector Core Laboratory for the Gene Therapy Resource Program (GTRP) produces large-scale, pre-clinical grade vectors, immunology testing services, vector design consultative services, and vector biodistribution testing for GTRP-approved investigators.

基因治疗资源计划（GTRP）的临床前媒介核心实验室生产大规模的，临床前的矢量，免疫学测试服务，矢量设计咨询服务以及GTRP批准的媒介生物分配测试。