Passive Antibody Protection In The Setting Of Active Cel
Passive Antibody Protection In The Setting Of Active Cel
批准号:
6822169
负责人:
John R Mascola
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Current HIV vaccine candidates elicit reasonably potent cellular immune responses, but only low levels of neutralizing antibodies. Such CTL based vaccines (e.g., those based on DNA immunization) do not prevent infection, but can have a beneficial effect on disease course. In contrast, passively infused antibodies can provide complete protection, but must be administered in doses that result in serum antibody levels much higher than can be generated by current immunization strategies. In order to assess if CTL could combine with antibody to produce sterile immunity, we studied the effect of a suboptimal dose of neutralizing antibodies in animals with active immunity induced by IL2 adjuvanted DNA immunization.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
PASSIVE ANTIBODY PROTECTION IN SHIV CHALLENGE MODEL
-
批准号:6056489
-
项目类别:
-
资助金额:$34.43万
-
财政年份:1997
-
负责人:John R Mascola
-
依托单位:
PASSIVE ANTIBODY PROTECTION IN SHIV CHALLENGE MODEL
-
批准号:2536820
-
项目类别:
-
资助金额:$34.43万
-
财政年份:1997
-
负责人:John R Mascola
-
依托单位:
PASSIVE ANTIBODY PROTECTION IN SHIV CHALLENGE MODEL
-
批准号:2771638
-
项目类别:
-
资助金额:$34.43万
-
财政年份:1997
-
负责人:John R Mascola
-
依托单位:
Immunogenicity Studies of HIV-1 immunogens
-
批准号:6987254
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Non-human Primate Immunogenicity Studies of HIV-1 immuno
-
批准号:7174912
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Non Human Primate Models of SIV and HIV Immune Protection
-
批准号:7732732
-
项目类别:
-
资助金额:$30.51万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Preclinical Evaluation Of Neutralizing Antibodies Elicit
-
批准号:6684230
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Non-human Primate Immunogenicity Studies Of Dna Prime, R
-
批准号:6684228
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Evaluation Of Neutralizing Antibodies Elicited by HIV-1
-
批准号:7174913
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Macaque studies of correlates of HIV protection
-
批准号:7174910
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Preclinical Evaluation Of Neutralizing Antibodies Elicit
-
批准号:6822207
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Measurement of HIV Neutralization
-
批准号:6987252
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Preclinical Evaluation Of Neutralizing Antibodies Elicit
-
批准号:7299813
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Measurement of HIV Neutralization Using Flow Cytometric
-
批准号:7299810
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Non-human Primate Immunogenicity Studies of HIV-1 immuno
-
批准号:7299811
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Measurement of HIV Neutralization Using Flow Cytometric
-
批准号:7174911
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Passive Antibody Protection In The Setting Of Active Cel
-
批准号:6684226
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Non-human Primate Immunogenicity Studies of HIV-1 immunogens
-
批准号:7592382
-
项目类别:
-
资助金额:$21.79万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Optimizing Measurement Of Hiv-1 Neutralization Using A F
-
批准号:6684227
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
Preclinical Evaluation Of Neutralizing Antibodies Elicited by HIV-1 Immunogens
-
批准号:7732735
-
项目类别:
-
资助金额:$32.02万
-
财政年份:--
-
负责人:John R Mascola
-
依托单位:
国内基金
海外基金
登录
查看更多内容
基于多组学技术研究肠道微生物在猕猴(Macaca mulatta)衰老过程中的作用机制
-
批准号:32370450
-
项目类别:面上项目
-
资助金额:50万元
-
批准年份:2023
-
负责人:范振鑫
-
依托单位:
太行山猕猴(Macaca mulatta tcheliensis)雌性的配偶选择
-
批准号:32070446
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2020
-
负责人:路纪琪
-
依托单位:
猕猴(Macaca mulatta)衰老过程中凝血功能变化规律及基因表达调控机制研究
-
批准号:--
-
项目类别:--
-
资助金额:58万元
-
批准年份:2020
-
负责人:范振鑫
-
依托单位:
猕猴(Macaca mulatta)衰老过程中凝血功能变化规律及基因表达调控机制研究
-
批准号:32070413
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2020
-
负责人:范振鑫
-
依托单位:
太行山猕猴(Macaca mulatta tcheliensis)雌性的配偶选择
-
批准号:--
-
项目类别:--
-
资助金额:58万元
-
批准年份:2020
-
负责人:路纪琪
-
依托单位:
猕猴(Macaca mulatta)亚种及其近缘种比较基因组学研究
-
批准号:31471989
-
项目类别:面上项目
-
资助金额:85.0万元
-
批准年份:2014
-
负责人:刘志瑾
-
依托单位: