Science Education of Alcohol Metabolism

描述（由申请人提供）：人类消费酒精是普遍存在的。虽然据报道，90%的人口消费不同数量的酒精，但只有少数但数量可观的人口滥用酒精消费。据估计，10-20%的男性和3-10%的女性会出现持续的酒精相关问题。青少年饮酒问题仍然是我国一个重要的健康问题。青少年滥用酒精的情况正在增加，过度饮酒会对个人、家庭和社会造成心理、社会和身体伤害。在拟议的第二阶段奖励期间，研究将完成，新的实验和试剂将在车间和教室环境中进行测试，然后在第三阶段进行营销。公司在科教市场立足，以优质的产品、技术和教育服务、有竞争力的价格赢得了良好的声誉。这些评估将由讲习班参与者和课堂学生和教师进行测试和使用。学习评估的测量将基于与两个学术教师的合作，以消除这些研究中可能存在的偏见。公共卫生相关性：青少年使用酒精是我国一个重要的卫生重点，青少年滥用酒精的情况正在增加。过度饮酒会对个人、家庭和社会造成心理、社会和身体伤害。全国范围内的学龄学生报告说，至少有一次饮用五杯或五杯以上有害饮酒。青少年饮酒还会导致学习成绩差、犯罪和社会不适应。同样令人担忧的是，有证据表明，早期饮酒与成人酗酒发展之间存在高度相关性。这项SBIR的目的是对7至12年级的学生进行研究，并在第三阶段进行市场实验，以了解酒精是如何代谢的，以及个体之间代谢率的差异。

DESCRIPTION (provided by applicant): Human consumption of alcohol is ubiquitous. While it is reported that ninety percent of the population consumes various amounts of alcohol, only a small but sizable minority of the population abuse alcohol consumption. It is estimated that 10-20% of males and 3-10% of females develop persistent alcohol-related problems. Alcohol use by youth continues to be an important health focus for our Nation. Alcohol misuse among adolescents is on the increase, and excessive drinking is associated with psychological, social and physical harm to the individual, family and society. During the proposed Phase II award period, research will be completed and new experiments and reagents will be tested in workshop and classroom settings prior to the marketing in Phase III. The Company is well established in the science education market and enjoys a fine reputation for its high quality products, technical and education service, and competitive prices. The assessments will be tested and used by workshop participants and classroom students and teachers. Measurement of learning assessments will be based on collaborations with two academic faculty to remove possible bias in these studies. PUBLIC HEALTH RELEVANCE: Alcohol use by youth is an important health focus for our Nation and alcohol misuse among adolescents is on the increase. Excessive drinking is associated with psychological, social and physical harm to the individual, family and society. School age students nationwide report episodes of hazardous drinking of five or more drinks on at least one occasion. Adolescent drinking also leads to poor school performance, criminal involvement and social maladjustments. Equally alarming is evidence that suggests a high correlation between the early-onset of alcohol consumption and the development of alcoholism in adults. The aim of this SBIR is to research and in Phase III to market experiments for grades 7 to 12 on understanding how alcohol is metabolized and that there are differences in the rate of metabolism amongst individuals.