Science Education of Alcohol Metabolism

酒精代谢科普教育

• 批准号: 7695054
• 负责人: Karen Graf
• 金额: $ 51.87万
• 依托单位: EDVOTEK, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-02-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7695054
• 关键词: Acetaldehyde; Achievement; Adolescence; Adolescent; Adult; Affect; Alcohol consumption; Alcoholism; Alcohols; Alleles; Award; Awareness; Bacteria; Behavioral; Biochemical; Biochemistry; Biohazardous Substance; Biological; Biological Assay; Biology; Biotechnology; Cladocera; Collaborations; Community Health; Complement; DNA; Daphnia; Decision Making; Development; Digestion; Drosophila genus; Dyes; Education; Educational Status; Educational process of instructing; Educational workshop; Enzymes; Equipment; Ethanol; Ethanol Metabolism; Ethical Issues; Ethnic Origin; Faculty; Family; Female; Gender; Genes; Genetic; Genetic Polymorphism; Genetic Variation; Genotype; Health; Health education; Heart Rate; Heavy Drinking; Human; Human Genetics; Indiana; Individual; Invertebrates; Investigation; Laboratories; Learning; Left; Link; Marketing; Measurement; Measures; Metabolic; Metabolism; Minority; Molecular Biology; NADH; National Institute on Alcohol Abuse and Alcoholism; National Research Council; Organism; Parents; Participant; Performance; Pharmaceutical Preparations; Phase; Plasmids; Population; Price; Process; Public Health; Publishing; Race; Reaction; Reagent; Reporting; Research; Resources; Restriction fragment length polymorphism; Role; Sampling; School Teachers; School-Age Population; Schools; Science; Services; Simulate; Small Business Innovation Research Grant; Societies; Students; Technology; Temperature; Testing; Time; Tobacco; Toxic effect; Toxin; Translating; United States; United States National Institutes of Health; Universities; Validation; Variant; Youth; alcohol effect; alcohol misuse; alcohol related problem; base; college; data sharing; design; drinking; early onset; genetic strain; hazardous drinking; high school; male; middle school; programs; psychologic; public health relevance; research study; restriction enzyme; science education; social; symposium; teacher; underage drinking; web site

DESCRIPTION (provided by applicant): Human consumption of alcohol is ubiquitous. While it is reported that ninety percent of the population consumes various amounts of alcohol, only a small but sizable minority of the population abuse alcohol consumption. It is estimated that 10-20% of males and 3-10% of females develop persistent alcohol-related problems. Alcohol use by youth continues to be an important health focus for our Nation. Alcohol misuse among adolescents is on the increase, and excessive drinking is associated with psychological, social and physical harm to the individual, family and society. During the proposed Phase II award period, research will be completed and new experiments and reagents will be tested in workshop and classroom settings prior to the marketing in Phase III. The Company is well established in the science education market and enjoys a fine reputation for its high quality products, technical and education service, and competitive prices. The assessments will be tested and used by workshop participants and classroom students and teachers. Measurement of learning assessments will be based on collaborations with two academic faculty to remove possible bias in these studies. PUBLIC HEALTH RELEVANCE: Alcohol use by youth is an important health focus for our Nation and alcohol misuse among adolescents is on the increase. Excessive drinking is associated with psychological, social and physical harm to the individual, family and society. School age students nationwide report episodes of hazardous drinking of five or more drinks on at least one occasion. Adolescent drinking also leads to poor school performance, criminal involvement and social maladjustments. Equally alarming is evidence that suggests a high correlation between the early-onset of alcohol consumption and the development of alcoholism in adults. The aim of this SBIR is to research and in Phase III to market experiments for grades 7 to 12 on understanding how alcohol is metabolized and that there are differences in the rate of metabolism amongst individuals.

描述（由申请人提供）：人类饮酒普遍存在。虽然据报道，90%的人口消费不同数量的酒精，但只有一小部分人滥用酒精消费。据估计，10-20%的男性和3-10%的女性患有持续的酒精相关问题。青少年饮酒仍然是我们国家的一个重要健康问题。青少年滥用酒精的现象正在增加，过度饮酒与对个人、家庭和社会的心理、社会和身体伤害有关。在拟议的第二阶段奖励期间，将完成研究，并在第三阶段上市之前在车间和教室环境中测试新的实验和试剂。本公司在科学教育市场上建立了良好的基础，并以其高质量的产品，技术和教育服务以及具有竞争力的价格享有良好的声誉。这些评估将由讲习班参与者和课堂学生和教师进行测试和使用。学习评估的测量将基于与两个学术教师的合作，以消除这些研究中可能存在的偏见。公共卫生相关性：青少年饮酒是我们国家的一个重要健康问题，青少年滥用酒精的情况正在增加。过量饮酒会对个人、家庭和社会造成心理、社会和身体上的伤害。全国范围内的学龄学生报告至少有一次喝了五杯或五杯以上的危险饮料。青少年饮酒还导致学习成绩差、犯罪和社会适应不良。同样令人震惊的是，有证据表明，成年人早期饮酒与酗酒之间存在高度相关性。这个SBIR的目的是研究和在第三阶段市场实验7至12年级了解酒精是如何代谢的，并有不同的代谢率之间的个人。