RETRAINING AUTOMATIC BIASES RELATED TO PROBLEM DRINKING IN COLLEGE STUDENTS

描述（由申请人提供）：提议的独立之路奖的主要目标是加速和完成克里斯汀·林格伦博士在酒精研究方面的培训，并启动她作为一名独立科学家的职业生涯，并获得终身助理教授的职位。林德格伦博士是一位心理学家，也是华盛顿大学NIAAA T32培训基金的博士后研究员。为期2年的K99阶段将完成Lindgren博士在与酒精使用障碍病因学和预防相关的行为方法方面的培训，重点是自动过程的作用（即自动发生的过程，没有意识控制）。在监督下，Lindgren博士将完成(a)一项正在进行的自动和控制过程的纵向调查，以及它们在大学女性饮酒和性侵犯问题中的作用；(b)与成瘾行为和多层次统计相关的课程。Lindgren博士还将把一部分时间用于传播研究成果，包括准备和提交手稿、与酒精和自动流程方面的专家进行磋商，以及为全国求职准备材料。拟议的导师，博士。邻居格林沃尔德和凯森分别是大学饮酒、自动社会认知和性受害方面的专家，他们与林德格伦博士保持着持续的指导关系。华盛顿大学是一所世界级的研究机构，拥有完成K99目标所需的资源。为期3年的ROO阶段将允许Lindgren博士建立她的实验室，进行3项研究，并准备并向NIAAA提交R01。这些研究扩展了Lindgren博士对自动过程和问题饮酒的研究，以调查(a)再培训自动过程的可行性和(b)再培训在减少酒精消费和问题方面的效用。具体来说，这些研究将识别和再训练预测大量饮酒的自动关联，并调查再训练对饮酒的影响。这些研究还将为Lindgren博士提交的R01报告提供试点数据。该提议的奖励与NIH增加和维持强大的独立研究人员队伍以满足国家行为和临床研究需求的目标是一致的。这项研究的重点是减少高危人群（未成年饮酒者）的饮酒，并将基础科学方法转化为应用课题（酒精消费），这与NIAAA的使命高度一致。

DESCRIPTION (provided by applicant): The major objectives of the proposed Pathway to Independence Award are the acceleration and completion of Dr. Kristen Lindgren's training in alcohol research and the launching of her career as an independent scientist with a tenure-track assistant professor position. Dr. Lindgren is a psychologist and a postdoctoral fellow on an NIAAA T32 training grant at the University of Washington (UW). The 2-year K99 Phase will complete Dr. Lindgren's training in behavioral approaches related to the etiology and prevention of alcohol use disorders, with an emphasis on the role of automatic processes (i.e., processes that occur automatically, without conscious control). With supervision, Dr. Lindgren will complete (a) an on-going longitudinal investigation of automatic and controlled processes and their role in problem drinking and sexual assault in college women and (b) coursework related to addictive behaviors and multi-level statistics. Dr. Lindgren will also dedicate a portion of her time to dissemination of research findings through manuscript preparation and submission, consultation with experts on alcohol and automatic processes, and preparation of materials for a national job search. The proposed mentors, Drs. Neighbors, Greenwald, & Kaysen, are experts in college drinking, automatic social cognition, and sexual victimization, respectively, and have on-going mentoring relationships with Dr. Lindgren. UW is a world-class research institution, with the resources necessary to complete the aims of the K99. The 3-year ROO Phase will allow Dr. Lindgren to establish her laboratory, conduct 3 studies, and prepare and submit an R01 to NIAAA. Those studies extend Dr. Lindgren's research on automatic processes and problem drinking to investigate (a) the feasibility of retraining automatic processes and (b) the utility of retraining in reducing alcohol consumption and problems. Specifically, these studies will identify and retrain automatic associations predictive of heavy drinking and investigate retraining's influence on drinking. The studies will also provide pilot data for Dr. Lindgren's R01 submission. The proposed award is accordant with NIH's goal of increasing and maintaining a strong cohort of independent investigators to address the Nation's behavioral and clinical research needs. With its emphasis on reducing drinking in high-risk populations (underage drinkers) and on translating basic science methods to applied topics (alcohol consumption), the proposed research is highly consistent with NIAAA's mission.