RETRAINING AUTOMATIC BIASES RELATED TO PROBLEM DRINKING IN COLLEGE STUDENTS

描述(由申请人提供)：拟议的独立之路奖的主要目标是加快和完成克里斯汀·林德格伦博士在酒精研究方面的培训，并开始她作为一名独立科学家的职业生涯，并获得终身教职助理教授的职位。林格伦博士是一名心理学家，也是华盛顿大学(UW)NIAAA T32培训基金的博士后研究员。为期两年的K99阶段将完成林德格伦博士在与酒精使用障碍的病因和预防相关的行为方法方面的培训，重点是自动过程(即自动发生的、没有意识控制的过程)的作用。在监督下，林德格伦博士将完成(A)对自动和受控过程及其在女大学生饮酒和性侵犯问题中的作用的持续纵向调查，以及(B)与成瘾行为和多层次统计相关的课程工作。林德格伦博士还将投入一部分时间，通过准备和提交手稿、咨询酒精和自动程序方面的专家，以及为全国求职准备材料来传播研究成果。被提名的导师邻居博士、格林沃尔德博士和凯森博士分别是大学饮酒、自动社会认知和性侵害方面的专家，并与林德格伦博士保持着持续的指导关系。威斯康星大学是一家世界级的研究机构，拥有完成K99目标所需的资源。为期3年的Roo阶段将允许Lindgren博士建立她的实验室，进行3项研究，并准备并向NIAAA提交R01。这些研究扩展了林德格伦博士对自动饮酒和问题饮酒的研究，以调查(A)再培训自动饮酒过程的可行性，以及(B)再培训在减少饮酒和饮酒问题方面的效用。具体地说，这些研究将识别和再培训预测重度饮酒的自动关联，并调查再培训对饮酒的影响。这些研究还将为林德格伦博士提交的R01报告提供试点数据。拟议的奖励符合NIH的目标，即增加和保持一支强大的独立研究人员队伍，以满足国家的行为和临床研究需求。由于其重点是减少高危人群(未成年饮酒者)的饮酒，并将基础科学方法转化为应用主题(酒精消费)，拟议的研究与NIAAA的使命高度一致。

DESCRIPTION (provided by applicant): The major objectives of the proposed Pathway to Independence Award are the acceleration and completion of Dr. Kristen Lindgren's training in alcohol research and the launching of her career as an independent scientist with a tenure-track assistant professor position. Dr. Lindgren is a psychologist and a postdoctoral fellow on an NIAAA T32 training grant at the University of Washington (UW). The 2-year K99 Phase will complete Dr. Lindgren's training in behavioral approaches related to the etiology and prevention of alcohol use disorders, with an emphasis on the role of automatic processes (i.e., processes that occur automatically, without conscious control). With supervision, Dr. Lindgren will complete (a) an on-going longitudinal investigation of automatic and controlled processes and their role in problem drinking and sexual assault in college women and (b) coursework related to addictive behaviors and multi-level statistics. Dr. Lindgren will also dedicate a portion of her time to dissemination of research findings through manuscript preparation and submission, consultation with experts on alcohol and automatic processes, and preparation of materials for a national job search. The proposed mentors, Drs. Neighbors, Greenwald, & Kaysen, are experts in college drinking, automatic social cognition, and sexual victimization, respectively, and have on-going mentoring relationships with Dr. Lindgren. UW is a world-class research institution, with the resources necessary to complete the aims of the K99. The 3-year ROO Phase will allow Dr. Lindgren to establish her laboratory, conduct 3 studies, and prepare and submit an R01 to NIAAA. Those studies extend Dr. Lindgren's research on automatic processes and problem drinking to investigate (a) the feasibility of retraining automatic processes and (b) the utility of retraining in reducing alcohol consumption and problems. Specifically, these studies will identify and retrain automatic associations predictive of heavy drinking and investigate retraining's influence on drinking. The studies will also provide pilot data for Dr. Lindgren's R01 submission. The proposed award is accordant with NIH's goal of increasing and maintaining a strong cohort of independent investigators to address the Nation's behavioral and clinical research needs. With its emphasis on reducing drinking in high-risk populations (underage drinkers) and on translating basic science methods to applied topics (alcohol consumption), the proposed research is highly consistent with NIAAA's mission.