EARLY-ONSET SEPSIS AN NICHD/CDC SURVEILLANCE STUDY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项前瞻性队列研究。将对出生在网络中心的被诊断为早发性败血症和/或脑膜炎的婴儿进行深入跟踪。 目标是： 1.建立目前以医院为基础的足月儿和早产儿在产前抗生素预防时代的EOS比率。 2.监测所有出生体重和胎龄的新生儿中与EOS和脑膜炎有关的微生物。 3.比较无症状儿和有症状儿的发病年龄和病原菌。 4.按病原菌分组监测EOS婴儿败血症相关死亡率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a prospective cohort study. The cohort of infants born at Network centers who are diagnosed to have early-onset sepsis and/or meningitis will be followed in depth. Aims are to: 1. To establish current hospital-based rates of EOS among term and preterm infants in he era of intrapartum antibiotic prophylaxis. 2. To monitor the organisms associated with EOS and meningitis in neonates of all birthweights and gestational ages. 3. To compare asymptomatic and symptomatic infants by gesational age and pathogen. 4. To monitor sepsis-associated mortality rates for infants with EOS, by pathogen group.