SLEEP DEPRIVATION AND COGNITIVE PROCESSING: AN FMRI STUDY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究有两个具体目标。 第一个目的是检验睡眠剥夺会干扰复杂认知能力初始获得的假设。 A.为了验证这一点，他们将测试一个假设，即正常的夜间睡眠可以成功获得几种复杂的认知能力。B。他们还将测试一个假设，即一个晚上的睡眠剥夺会显着损害几个复杂的认知能力的获得。C.测试假设，相对于正常的睡眠，睡眠剥夺会改变大脑在获得几种复杂认知能力过程中的激活模式。 本研究的第二个目的是检验睡眠剥夺会干扰随后的复杂认知能力巩固的假设。A.测试以下假设：在初始获得之后，随后的正常睡眠可以成功巩固，从而在几天后保留几种复杂的认知能力; B。测试以下假设：在最初获得之后，随后一夜的睡眠剥夺会干扰巩固，从而在几天后阻止几种复杂认知能力的保留。C.测试以下假设：相对于正常的后续睡眠，睡眠剥夺会改变后来回忆几种复杂认知能力时的大脑激活模式。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. There are two specific aims of this study. The first aim is to test the hypothesis that sleep deprivation interferes with the initial acquisition of complex cognitive abilities. A. To test this they will test the hypothesis that a normal night of prior sleep allows successful acquisition of several complex cognitive abilities. B. They will also test the hypothesis that a night of prior sleep deprivation will significantly impair the acquisition of several complex cognitive abilities. C. Test the hypothesis that, relative to a normal night of sleep, sleep deprivation alters the pattern of brain activation during the acquisition of several complex cognitive abilities. The second aim of this study is to test the hypothesis that sleep deprivation interferes with the subsequent consolidation of complex cognitive abilities. A. Test the hypothesis that, following initial acquisition, a normal night of subsequent sleep allows successful consolidation and thus retention of several complex cognitive abilities days later; B. Test the hypothesis that, following initial acquisition, a night of subsequent sleep deprivation interferes with consolidation and thus blocks the retention of several complex cognitive abilities days later. C. Test the hypothesis that, relative to a normal night of subsequent sleep, sleep deprivation alters the pattern of brain activation during the later recall of several complex cognitive abilities.