SLEEP DEPRIVATION AND COGNITIVE PROCESSING: AN FMRI STUDY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本研究有两个具体目的。第一个目的是检验睡眠剥夺会干扰复杂认知能力的初始获得这一假设。答：为了测试这一点，他们将测试这样一种假设，即正常的先前睡眠可以成功地获得几种复杂的认知能力。B.他们还将检验这样一种假设，即事先睡眠不足一夜会显著损害几种复杂认知能力的获得。C.测试一种假设，即相对于正常的夜间睡眠，睡眠剥夺会改变大脑在获得几种复杂认知能力的过程中的激活模式。这项研究的第二个目的是检验睡眠剥夺会干扰随后复杂认知能力的巩固这一假设。A.测试一种假设，即在最初获得后，正常的一夜睡眠可以成功巩固，从而在几天后保留几种复杂的认知能力；B.测试一种假设，即在最初获得之后，一夜的后续睡眠剥夺会干扰巩固，从而阻止几天后几种复杂认知能力的保留。C.测试这样一种假设，即相对于随后的正常夜间睡眠，睡眠剥夺会改变大脑在后来对几种复杂认知能力的回忆中的激活模式。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. There are two specific aims of this study. The first aim is to test the hypothesis that sleep deprivation interferes with the initial acquisition of complex cognitive abilities. A. To test this they will test the hypothesis that a normal night of prior sleep allows successful acquisition of several complex cognitive abilities. B. They will also test the hypothesis that a night of prior sleep deprivation will significantly impair the acquisition of several complex cognitive abilities. C. Test the hypothesis that, relative to a normal night of sleep, sleep deprivation alters the pattern of brain activation during the acquisition of several complex cognitive abilities. The second aim of this study is to test the hypothesis that sleep deprivation interferes with the subsequent consolidation of complex cognitive abilities. A. Test the hypothesis that, following initial acquisition, a normal night of subsequent sleep allows successful consolidation and thus retention of several complex cognitive abilities days later; B. Test the hypothesis that, following initial acquisition, a night of subsequent sleep deprivation interferes with consolidation and thus blocks the retention of several complex cognitive abilities days later. C. Test the hypothesis that, relative to a normal night of subsequent sleep, sleep deprivation alters the pattern of brain activation during the later recall of several complex cognitive abilities.