SLEEP DEPRIVATION AND COGNITIVE PROCESSING: AN FMRI STUDY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. There are two specific aims of this study. The first aim is to test the hypothesis that sleep deprivation interferes with the initial acquisition of complex cognitive abilities. A. To test this they will test the hypothesis that a normal night of prior sleep allows successful acquisition of several complex cognitive abilities. B. They will also test the hypothesis that a night of prior sleep deprivation will significantly impair the acquisition of several complex cognitive abilities. C. Test the hypothesis that, relative to a normal night of sleep, sleep deprivation alters the pattern of brain activation during the acquisition of several complex cognitive abilities. The second aim of this study is to test the hypothesis that sleep deprivation interferes with the subsequent consolidation of complex cognitive abilities. A. Test the hypothesis that, following initial acquisition, a normal night of subsequent sleep allows successful consolidation and thus retention of several complex cognitive abilities days later; B. Test the hypothesis that, following initial acquisition, a night of subsequent sleep deprivation interferes with consolidation and thus blocks the retention of several complex cognitive abilities days later. C. Test the hypothesis that, relative to a normal night of subsequent sleep, sleep deprivation alters the pattern of brain activation during the later recall of several complex cognitive abilities.