BIOINFORMATICS CORE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 缅因州INBRE生物信息学核心通过提供必要的软件、访问分子数据库和生物医学期刊以及数据存储能力来促进数据管理和分析。 该核心还支持缅因州INBRE网站和INBRE机构通信网络的开发，以促进多中心研究和资源共享以及数据的保密交换。 生物信息学能力随着在线访问额外的序列分析工具和定制序列数据集而增加。 核心扩展了可用软件的范围，包括用于基序发现，建立自动化工作流程和聚类表达序列标签（EST）的程序。 该中心继续促进比较基因组学研究，办法是提供宝贵的生物学数据库的在线访问，在线订阅《自然》系列期刊，并在国家生物研究所支助的本科生课程和初级教员会议上介绍生物信息学。 网络存储设备和磁带库的安装提高了研究项目计算和显微镜部分的数据存储能力，并确保了国家边界研究所支持的科学数据得到保护。 通信能力得到扩大，安装了多点会议单元，可自动安排多达20个机构参加的视频会议。 缅因州国家建筑研究所网站的内容得到了大幅加强。 主要增加的内容包括关于初级教师及其研究项目的信息，核心资源，缅因州INBRE计划的新闻和事件，以及初级教师的赠款和行政支持信息。生物信息学研究和研究人员的交流需求将继续得到评估，并反映在网站和核心资源的持续开发中。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Maine INBRE Bioinformatics Core facilitates data management and analysis by providing essential software, access to molecular databases and biomedical journals and capabilities for data storage. The Core also supports development of the Maine INBRE website and communication networks for INBRE institutions to facilitate multi-center research and resource sharing and the confidential exchange of data. Bioinformatics capabilities increased with online access to additional sequence analysis tools and custom sequence data sets. The Core expanded the spectrum of available software to include programs for motif-finding, establishing automated workflows and clustering Expressed Sequence Tags (ESTs). The Core continued to facilitate comparative genomics research by providing online access to valuable biological databases, online subscriptions to the Nature suite of journals and by providing bioinformatics presentations at INBRE-supported undergraduate courses and junior faculty meetings. Implementation of a networked storage device and tape library enhanced the data storage capacity for computational and microscopy components of research projects and ensured the protection of INBRE-supported scientific data. Communications capabilities expanded with the implementation of a multipoint conferencing unit, which enables automated scheduling of videoconference meetings involving up to 20 institutions. The content of the Maine INBRE website was enhanced substantially. Major additions include information about junior faculty and their research projects, Core resources, news and events of the Maine INBRE program and grant and administrative support information for junior faculty. The bioinformatics research and communication needs of investigators continue to be evaluated and reflected in ongoing development of the website and Core resources.