EXERCISE AND TYPE 2 DIABETES: GENDER AND ENDOTHELIAL FUNCTION

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究旨在评估2型糖尿病男性和女性血管内皮和舒张期功能的变化与整体运动表现的关系。我们希望回答的一个主要问题是，2型糖尿病对女性循环系统和运动能力的负面影响是否比男性更大。其次，我们还将确定运动训练是否可以恢复女性和男性的内皮和舒张期功能以及运动能力，以及这些变化在女性2型糖尿病患者中是否比男性更大。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study was designed to evaluate changes in endothelial and diastolic function in relation to overall exercise performance in men and women with Type 2 diabetes. One major question we are hoping to answer is whether Type 2 diabetes more adversely affects the circulatory system and exercise capacity in women than in men. Secondarily, we will also determine if exercise training can restore endothelial and diastolic function as well as exercise capacity in women and men and if these changes are greater in women than men with Type 2 diabetes.