IMPACT OF SEROTONIN REUPTAKE INHIBITORS ON SEX HORMONE LEVELS

血清素再摄取抑制剂对性激素水平的影响

• 批准号: 7604229
• 负责人: MARGARET ALTEMUS
• 金额: $ 0.32万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604229
• 关键词: Adverse effects; Androgens; Antidepressive Agents; Blood Circulation; Computer Retrieval of Information on Scientific Projects Database; Funding; Gonadal Steroid Hormones; Grant; Hormones; Institution; Pharmaceutical Preparations; Production; Research; Research Personnel; Resources; Selective Serotonin Reuptake Inhibitor; Source; United States National Institutes of Health; steroid hormone

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The broad objective of the study is to determine whether sexual side effects common with SSRI medications may be associated with the medication's effect on gonadal steroid hormones. The study investigates the hypothesis that serotonin reuptake inhibitors (SSRI) antidepressants suppress production of steroid hormones. And additional hypothesis is that there will be an association between the emergence of sexual side effects after starting an SSRI given the decrease in circulation levels of androgen hormones.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的主要目的是确定SSRI药物常见的性副作用是否与药物对性腺类固醇激素的影响有关。这项研究调查了5-羟色胺再摄取抑制剂(SSRI)抗抑郁药抑制类固醇激素产生的假设。另一个假设是，考虑到雄激素循环水平的下降，在开始SSRI后出现的性副作用之间将存在关联。