DOPAMINE/RESTLESS LEG SYNDROME

多巴胺/不宁腿综合症

基本信息

  • 批准号:
    7604602
  • 负责人:
  • 金额:
    $ 0.26万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2006
  • 资助国家:
    美国
  • 起止时间:
    2006-12-01 至 2007-09-16
  • 项目状态:
    已结题

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Restless Legs Syndrome (RLS) is a neurological disorder that is reported to effect between 2-5% of the population. RLS is a sensory-motor disorder that respond to dopamine treatment. RLS prevalence is consistently higher that the population prevalence for iron deficiency, pregnancy, and end-stage renal disease. Although the pathophysiology of RLS remains unknown, evidence does suggest a role for the dopaminergic (DA) system for brain iron deficiency. We propose to test that RLS symptoms are a result of compensation for an increase in the circadian amplitude of dopaminergic activity. We propose that there is a dynamic change in the system over its circadian cycle, not just a single time-of-day decrement in dopamine at night.
这个子项目是众多研究子项目之一

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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CHRISTOPHER J EARLEY其他文献

CHRISTOPHER J EARLEY的其他文献

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{{ truncateString('CHRISTOPHER J EARLEY', 18)}}的其他基金

Lymphocyte CpG methylation changes and brain pathology in Restless Legs Syndrome
不宁腿综合征中淋巴细胞 CpG 甲基化的变化和脑病理学
  • 批准号:
    9921504
  • 财政年份:
    2017
  • 资助金额:
    $ 0.26万
  • 项目类别:
Lymphocyte CpG methylation changes and brain pathology in Restless Legs Syndrome
不宁腿综合征中淋巴细胞 CpG 甲基化的变化和脑病理学
  • 批准号:
    10121614
  • 财政年份:
    2017
  • 资助金额:
    $ 0.26万
  • 项目类别:
Lymphocyte CpG methylation changes and brain pathology in Restless Legs Syndrome
不宁腿综合征中淋巴细胞 CpG 甲基化的变化和脑病理学
  • 批准号:
    9443755
  • 财政年份:
    2017
  • 资助金额:
    $ 0.26万
  • 项目类别:
Restless Legs Syndrome Scientific Meeting
不宁腿综合症科学会议
  • 批准号:
    7613531
  • 财政年份:
    2008
  • 资助金额:
    $ 0.26万
  • 项目类别:
IV IRON METABOLISM IN RLS
IV RLS 中的铁代谢
  • 批准号:
    7607451
  • 财政年份:
    2006
  • 资助金额:
    $ 0.26万
  • 项目类别:
SYSTEMIC IRON METABOLISM IN RESTLESS LEGS SYNDROME
不宁腿综合征的全身铁代谢
  • 批准号:
    7607473
  • 财政年份:
    2006
  • 资助金额:
    $ 0.26万
  • 项目类别:
DOPAMINE AND IRON IN RESTLESS LEG SYNDROME
多巴胺和铁在不宁腿综合症中的作用
  • 批准号:
    7607461
  • 财政年份:
    2006
  • 资助金额:
    $ 0.26万
  • 项目类别:
SUPPLEMENTAL INTRAVENOUS IRON THERAPY FOR RLS
不宁腿综合征的补充静脉铁剂治疗
  • 批准号:
    7607477
  • 财政年份:
    2006
  • 资助金额:
    $ 0.26万
  • 项目类别:
DOPAMINE-RLS CONNECTION
多巴胺-RLS 连接
  • 批准号:
    7604739
  • 财政年份:
    2006
  • 资助金额:
    $ 0.26万
  • 项目类别:
DOPAMINE-RLS CONNECTION
多巴胺-RLS 连接
  • 批准号:
    7604620
  • 财政年份:
    2006
  • 资助金额:
    $ 0.26万
  • 项目类别:

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