Training Program in Developmental Biology

发育生物学培训计划

• 批准号: 7617844
• 负责人: VICTORIA E. PRINCE
• 金额: $ 17.49万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7617844
• 关键词: Developmental Biology; Training Programs

DESCRIPTION (provided by applicant): The core mission of the proposed Developmental Biology Training Program is to produce highly qualified independent research scientists trained to take a broad interdisciplinary approach to developmental biology problems. The applicant PIs have built a longstanding (30 year) active training program centered around the Committee on Developmental Biology (CDB), which benefits from significant Institutional and programmatic support, a well-established course curriculum, and a group of 31 vibrant, well-funded faculty trainers. This program has a proven track record in recruiting highly qualified trainees who go on to successful research careers in academia and industry. NIH support will allow the PIs to formalize training of what is currently an informal grouping of trainees from within and beyond CDB. Trainees who matriculate to other degree-granting units such as Molecular Genetics and Cell Biology, Genetics, Neurobiology, and Organismal Biology & Anatomy, significantly enhance the interdisciplinary nature of the PIs' research and training endeavor. They propose a program that will ensure all trainees receive appropriate education in developmental biology, and of equal importance, facilitate interactions among trainees to enhance their learning experience. This mission is entirely consistent with the philosophy of the Division of Biological Sciences to avoid artificial boundaries and to encourage broad based interaction and collaboration. The DBTP trainers are a combination of experienced mentors and talented junior faculty. There are longstanding strengths in developmental genetics and the cellular basis of development processes. In addition, over the last decade the University of Chicago has built focus areas in developmental neurobiology and evolutionary developmental biology - the biannual student run symposium on the Developmental Basis of Evolutionary Change is one of the premiere national "Evo-Devo" meetings. The PIs request support for a total of six predoctoral trainees. They will support a combination of incoming students with clear interests in developmental biology, and students from related disciplines whose interests focus on developmental questions in the first year of study. A carefully designed curriculum has been developed including six formal courses in developmental biology, additional courses in molecular biology, genetics, cell biology, neurobiology, and evolutionary biology, and a wide range of supplemental activities including an annual retreat, journal club, and several seminar series. To enhance these training activities further the PIs propose to develop an annual one-day developmental biology symposium. The program should produce researchers trained in a variety of areas directly relevant to human health and disease. Developmental biology studies at the University of Chicago include the generation of animal disease models, studies of cancer and stem cell biology, as well as research into the underlying basis of birth defects that affect humans. The interactive environment within the Division of Biological Sciences allows collaborations that facilitate the movement of discoveries from the laboratory bench to the clinic.

描述(由申请人提供)：拟议的发育生物学培训计划的核心任务是培养高素质的独立研究科学家，他们接受培训，以广泛的跨学科方法解决发育生物学问题。申请者私人投资机构以发育生物学委员会(CDB)为中心，建立了一个长期(30年)的积极培训计划，该计划受益于重要的机构和方案支持、完善的课程设置和31名充满活力、资金充足的教员培训人员。该项目在招募高素质的受训人员方面有着良好的记录，这些受训人员将继续在学术界和工业界从事成功的研究工作。NIH的支持将使私人投资机构能够对目前来自国开行内外的非正式受训人员进行正式培训。被其他授予学位的单位录取的学员，如分子遗传学和细胞生物学、遗传学、神经生物学和组织生物学与解剖学，极大地增强了私人投资机构研究和培训工作的跨学科性质。他们提出了一项计划，确保所有受训者接受适当的发育生物学教育，同样重要的是，促进受训者之间的互动，以增强他们的学习体验。这一使命完全符合生物科学司的理念，即避免人为的界限，鼓励广泛的互动和合作。 DBTP培训师是经验丰富的导师和才华横溢的初级教员的组合。在发育遗传学和发育过程的细胞基础方面有长期的优势。此外，在过去的十年里，芝加哥大学在发育神经生物学和进化发育生物学方面建立了重点领域--一年两次的关于进化变化的发展基础的学生研讨会是全国首个“Evo-Devo”会议之一。私人投资机构要求为总共六名博士前实习生提供支持。他们将支持对发育生物学有明确兴趣的新生，以及在第一年学习时兴趣集中在发育问题上的相关学科的学生。精心设计的课程包括六门发育生物学的正式课程，分子生物学、遗传学、细胞生物学、神经生物学和进化生物学的额外课程，以及一系列的补充活动，包括年度静修、期刊俱乐部和几个研讨会系列。为了进一步加强这些培训活动，私人投资机构建议每年举办一次为期一天的发育生物学专题讨论会。 该计划应该培养出在与人类健康和疾病直接相关的各种领域接受过培训的研究人员。芝加哥大学的发育生物学研究包括动物疾病模型的建立、癌症和干细胞生物学的研究，以及对影响人类的出生缺陷的潜在基础的研究。生物科学司内部的互动环境允许进行协作，以促进将发现从实验室转移到临床。