Postdoctoral Training in Cardiovascular Disease

描述（由申请人提供）： 本申请要求为心血管疾病博士后培训计划的第二次竞争性更新提供资金。最初的培训计划是为外科住院医生设计的，为心血管科学的调查职业做准备。在第一次竞争性更新申请中，重点扩大到包括那些接受过心脏病学亚专业培训的人，他们希望致力于心血管科学基础方面的职业生涯。在第二次竞争性更新中，重点将继续放在具有外科和心脏病学亚专业培训的个人上，使他们能够参加为期2-3年的密集研究培训，从广泛的研究领域中选择，从分子生物学到结果/临床研究。哥伦比亚大学医学中心的心血管科学培训计划旨在加强和确保外科和心脏病医生-科学家的发展，旨在使这些年轻的研究人员能够在未来启动基于实验室的心血管科学研究计划。经过两个资助周期，很明显，该计划是非常成功地履行这一使命，培训外科住院医生和心脏病学研究员在基础研究方法和技术，转化和流行病学研究，并导致多个出版物和医生科学家的发展，其中大多数人已经或将继续，学术生涯的结果研究。在第二次竞争性更新中，我们将继续在基础调查方面取得卓越成就。每个子领域的范围都有所扩大，如基因治疗，细胞信号和免疫学，转化和结果研究等领域都有所扩大，血管生物学和离子通道研究的项目也有所扩大。两个新的计划，成果研究和临床科学，为申请人提供更大的机会，在优秀的设施和优秀的导师从事尖端的转化研究。利用哥伦比亚大学医学中心的基础科学家和临床研究人员的非凡深度，该培训计划旨在培养具有先进研究技术的医生科学家，但通过一系列核心讲座和教学计划提供个人关注，这些课程面向少数民族和/或妇女的优秀代表的内科医生和外科医生的研究培训。(End摘要）

DESCRIPTION (provided by applicant): This application requests funding for the second competitive renewal of a postdoctoral training program in cardiovascular diseases. Initially the training program was designed for surgical residents, to prepare for an investigative career in cardiovascular sciences. In the first competitive renewal application, the focus was broadened to include those individuals with cardiology subspeciality training, who wished to dedicate themselves to careers in fundamental aspects of cardiovascular science. In this second competitive renewal, the focus will continue to be on individuals with surgical and cardiology subspeciality training, enabling them to engage in an intensive 2-3 year research training, choosing from broad group of investigative areas, ranging from molecular biology to outcomes/clinical research. The training program in Cardiovascular Sciences at Columbia University Medical Center was conceived to enhance and ensure the development of surgical and cardiologist physician-scientists and was designed to enable such young investigators to initiate a laboratory-based research program in Cardiovascular Sciences in the future. After two funding cycles, it is evident that the program is extremely successful in fulfilling this mission, training surgical residents and cardiology fellows in basic research methodology and techniques, translational and epidemiologic research, and outcome studies leading to multiple publications and the development of physician-scientists, most of whom have, or will be going on, to academic careers. In this second competitive renewal, we will continue the excellence in basic investigation. The scope within each sub-area has been enlarged, and such areas as gene therapy, cell signaling and immunology, translational and outcome research have been expanded, as have the the programs in vascular biology and ion channel research. Two new programs, Outcomes Research and Clinical Sciences, offer the applicant even greater opportunities to engage in cutting-edge translational research in excellent facilities and with outstanding mentors. Utilizing the remarkable depth of basic scientists and clinical investigators within Columbia University Medical Center, this training program is powered to train physician-scientists with advanced research techniques, yet provide individual attention through a series of core lectures and didactic program geared towards the research training of physicians and surgeons with an excellent representation of minorities and/or women. (End of Abstract)