Developmental Biology Training Program

描述(申请人提供)：发育生物学领域在最近几年已经成熟，主要是通过生物科学中的许多学科的整合，包括遗传学、细胞生物学、胚胎学、生理学、分子生物学、生物化学和进化生物学。明尼苏达大学发育生物学的重点是由发育生物学中心提供的，该中心设在遗传学、细胞生物学和发育系-医学院和生物科学学院内的一个全大学系。发育生物学中心包括来自大学内许多其他系的成员，包括神经科学、儿科学、植物生物学、实验室医学和数学。发育生物学中心每年组织一次广受欢迎的明尼苏达大学发育生物学研讨会，每周和每月举办一系列发育生物学研究研讨会，研究生和博士后研究人员在会上展示他们的工作，并促进明尼苏达大学发育生物学家之间的互动和合作。培训员都是该中心的成员，使用许多不同的模式生物在发育生物学的不同领域开展工作，包括小鼠、斑马鱼、非洲爪哇、果蝇、线虫、网壳和拟南芥。发育生物学实习生的主要研究生课程是分子、细胞、发育生物学和遗传学(MCDB&G)研究生课程。该课程围绕实验室技术、分子生物学、遗传学、细胞生物学、发育生物学、文献分析和不同系统中的实验室轮换等强大的核心研究生课程而建立。培训师有强大的研究计划，以及致力于研究生和博士后培训的良好记录。五名博士前实习生将被选为培训补助金，主要来自MCDB&G的研究生，但也可能来自其他研究生项目，如神经科学和生物化学、分子生物学和生物物理学。受训者在培训者的实验室开始论文工作后，将得到一到三年的支持。培训实验室和核心设施都配备齐全。对发育的理解是许多现代医学的基础，最终将有助于对许多重大公共卫生问题的原因和可能的治疗方法的关键见解，从先天性出生缺陷到衰老。

DESCRIPTION (provided by applicant): The field of developmental biology has matured in recent years, largely through the integration of many disciplines within biological sciences, including genetics, cell biology, embryology, physiology, molecular biology, biochemistry, and evolutionary biology. The focus for developmental biology at the University of Minnesota is provided by the Developmental Biology Center, which is based in the Department of Genetics, Cell Biology, and Development - an all-University department within both the School of Medicine and the College of Biological Sciences. The Developmental Biology Center embraces members from many other departments within the University including Neuroscience, Pediatrics, Plant Biology, Laboratory Medicine, and Mathematics. The Developmental Biology Center organizes a popular annual University of Minnesota Developmental Biology Symposium, runs a weekly and monthly series of research seminars in developmental biology, where graduate students and postdoctoral researchers present their work, and promotes interactions and collaborations among developmental biologists at the University of Minnesota. The trainers are all members of the Center and work in diverse areas of developmental biology using many different model organisms, including mice, zebrafish, Xenopus, Drosophila, C. elegans, Dictyostelium, and Arabidopsis. The principal graduate program for developmental biology trainees is the Molecular, Cellular, Developmental Biology, and Genetics (MCDB&G) graduate program. This program is built around strong core graduate courses in laboratory techniques, molecular biology, genetics, cell biology, developmental biology, literature analysis, and laboratory rotations in diverse systems. The trainers have strong research programs and strong records of commitment to graduate and postdoctoral training. Five predoctoral trainees will be chosen for training grant support, largely from the pool of graduate students in MCDB&G but possibly also from other graduate programs, such as Neuroscience and Biochemistry, Molecular Biology and Biophysics. Trainees will be supported for one to three years, after they have begun their thesis work in the laboratories of the trainers. The training laboratories and core facilities are all well equipped. An understanding of development is fundamental to much of modern medicine and will ultimately contribute key insights into the causes of, and possible therapies for, many major public health problems ranging from congenital birth defects to senescence.