Multimodal Neuroimaging Training Program

_ 这项研究的目标是使新的跨学科培训计划的开发成为可能 集成两个组成部分1)NRSA博士前培训计划和2)短期研究！ 教育计划，其中将包括一个非NRSA博士前培训计划。已经有了很棒的 活体成像技术的进展，使神经科学家能够可视化分子、细胞和 系统生理和功能。要充分利用神经成像技术，重要的是要了解 基本原则、数据检测以及数据建模和可视化。此外，每种技术都有 有自己的长处和局限性。为了克服一种神经成像模式的弱点，它是 对于利用互补的成像方式是绝对必要的。通常，研究人员可能不会利用 先进的神经成像技术由于缺乏对这些方法的适当培训，因此 S教授对学生进行多种神经成像方法的原理和局限性的培训至关重要。为了 为了实现这一目标，我们建议为以下人员创建多模式神经成像培训计划(T90/R90) 博士和短期暑期学生，将由匹兹堡大学和 卡内基梅隆大学。这项计划将由神经基础研究中心管理 认知(CNBC)，它无缝地跨越两个研究所，是一项协调的跨学科研究 和具有国际地位的教育中心。博士前培训计划的具体目标是1) 教授综合神经成像研究的基础神经科学；2)教授潜在的原理、建模、 以及结构磁共振成像(MRI)、功能MRI、正电子发射的应用 从动物到人类的断层扫描、脑磁图和光学成像；3)集成 多种方法，开展多模式神经影像项目。为了达到特定的目标，学员将 参加核心课程、实验室轮换、研讨会，并参加年度务虚会。除 研究生T90/R90培训计划，短期多模式神经成像暑期学校(R90)是 建议为以下目标学生和研究人员讲授多模式神经成像的协同作用 有一种成像模式的经验，并希望将他们的培训扩展到其他模式。夏天 课程将由基础讲座、动手实验室工作坊和项目表演组成，强调 多种成像方式的方法学。我们提议的计划将为研究人员提供足够的培训 处理将多模式神经成像数据与知识相结合的日益复杂的问题 各种数据采集和处理方法，以及适当的解释。这将加快 多种影像手段在动物基础和临床神经科学研究中的协同应用 和人类。所有培训人员在有效的跨学科培训方面都有出色的记录， 合作研究。在本培训计划中开发的材料将通过网络分发。

_ The goal of this research is to enable the development of novel interdisciplinary training programs that ntegrate two components 1) an NRSA predoctoral training program and 2) a Short-Term Research! Education Program, which will include a non-NRSA predoctoral training program. There have been great advances in in vivo imaging techniques, which allow neuroscientists to visualize molecular, cellular and system physiology and functions. To fully utilize neuroimaging techniques, it is important to understand underlying principles, data detection, and data modeling and visualization. Furthermore, each technique has ts own strengths and limitations. In order to overcome the weakness of one neuroimaging modality, it is absolutely essential to utilize complementary imaging modalities. Often, researchers may not utilize advanced neuroimaging technologies due to the lack of proper training in these methodologies, therefore, it s crucial to train students the principles and limitations of multiple neuroimaging modalities. In order to achieve this goal, we propose to create the Multimodal Neuroimaging Training Program (T90/R90) for pre- doctoral and short-term summer students, which will be jointly run by the University of Pittsburgh and Carnegie Mellon University. This program will be administered by the Center for the Neural Basis of Cognition (CNBC), which seamlessly spans both institutes and is a coordinated interdisciplinary research and educational Center of international stature. Specific aims of the predoctoral training program are to 1) teach basic neuroscience for integrative neuroimaging research; 2) to teach underlying principles, modeling, and applications of structural magnetic resonance imaging (MRI), functional MRI, positron emission tomography, magnetoencephalography, and optical imaging from animals to humans; and 3) to integrate multiple methods and carry out multimodal neuroimaging projects. To achieve the specific aims, trainees will take core courses and laboratory rotations, seminars and participate in an annual retreat. In addition to the graduate T90/R90 training program, the short-term Multimodal Neuroimaging Summer School (R90) is proposed to teach the synergy of multi-modal neuroimaging for targeted students and investigators who have experience in one imaging modality and want to expand their training to other modalities. The summer program will consist of basic lectures, hand-on laboratory workshop, and performing projects, emphasizing the methodologies of multiple imaging modalities. Our proposed programwill train researchersfor adequate handling of the increasing complexity of combining multimodal neuroimaging data with the knowledge of various data acquisition and processing approaches, and appropriate interpretations. This will speed up the synergetic application of multiple imaging modalities to basic and clinical neuroscience research in animals and humans. All training faculty have an exceptional track record of effective interdisciplinary training and cooperative research.The materials developed in this Training Program will be distributed through the web.