NUCLEOSIDE TRANSPORTERS

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，不一定是研究者的机构。 疟疾是一种由疟原虫属原生动物寄生虫引起的疾病，是影响人类的最危险的传染病之一。这项研究的目的是确定帮助寄生虫在人体红细胞中繁殖的条件。从这项研究中获得的科学信息可能有助于了解这种疾病，并确定对抗疟疾的新药或疫苗。 实验室的研究将集中在人类疟疾寄生虫如何在人类红细胞内发展。我们的目标是在分子水平上表征寄生虫生存所必需的途径，并着眼于未来的药物开发。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Malaria, a disease caused by protozaon parasites of the genus Plasmodium, is one of the most dangerous infectious disease affecting human populations. The purpose of this research is to determine the conditions that help the multiplication of the parasite in human red blood cells. The scientific information received from this study may help understand the disease and identify new drugs or a vaccine against malaria. Research in the Lab will focus on how the Human Malaria Parasite develops within human red blood cells. Our goal is to characterize, at the molecular level, the pathways essential for the parasite survival with an eye toward future drug development.