HIGH RISK BREAST CANCER CLINIC

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The High Risk Breast Cancer Clinic (HRBCC) is not itself a research study but is a research resource designed to recruit individuals from families with an increased frequency of breast and ovarian cancer. Data and biospecimens from these individuals are then made available for research studies. The HRBCC is one of six international sites funded by the National Cancer Institute which comprise the Cooperative Family Registry for Breast Cancer Studies (CFRBCS). Locally, subjects are identified and referred by physicians throughout the region or are referred from previous studies of at-risk families. Individuals enrolling in the HRBCC provide data about family history, medical and demographic information, and cancer status and treatment. Blood samples are obtained, from which plasma, DNA, and lymphoblast cell lines are obtained. Subjects receive genetic education and counseling, and genetic testing when appropriate.