CLINICAL TRIAL: INVESTIGATION OF THE NATURAL HISTORY OF WEST NILE VIRUS INFECTIO

临床试验：西尼罗河病毒感染自然史的调查

• 批准号: 7716562
• 负责人: Diane E Goade
• 金额: $ 0.29万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7716562
• 关键词: Alabama; Basic Science; Clinical Research; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Disease; Education; Faculty; Funding; Grant; Immune response; Immunoglobulins; Infection; Institution; Investigation; Medicine; Mentors; Natural History; Neurology; Observational Study; Phase; Population Group; Research; Research Personnel; Resources; Risk; Safety; Source; Testing; United States National Institutes of Health; Virus; Virus Diseases; West Nile virus; prevent; treatment trial

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The divisions of Medicine and Neurology at UNM are responding to an emerging viral disease, West Nile Virus, by participating in NIH sponsored trials describing the natural history of illness and testing a new therapy. The proposed studies aim to 1) test safety and efficacy (phase I/II) of WN immune globulin in preventing or abrogating severe WN disease in high risk population groups, and 2) to define the natural history of WN infection. The proposed studies will integrate basic science and clinicalscience. Virus characterization and immune responses will take place at U. Alabama and at UNM. Clinical studies include an observational study and a Phase I/II treatment trial. Educational aspects include mentoring of fellows, residents and junior faculty who will be participating as new investigators on the trials.

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