EFFECT OF SULFUR AMINO ACID DEPLETION AND ACETAMINOPHEN (APAP) ON PLASMA GLUT

硫氨基酸消耗和对乙酰氨基酚 (APAP) 对血浆过剩的影响

• 批准号: 7603651
• 负责人: Dean Paul Jones
• 金额: $ 2.57万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603651
• 关键词: Acetaminophen; Acids; Chemical Exposure; Chemicals; Complex; Computer Retrieval of Information on Scientific Projects Database; Data; Diet; Funding; Glutathione; Grant; Individual; Institution; Measurement; Metabolic; Metabolism; NMR Spectroscopy; Oxidation-Reduction; Plasma; Research; Research Personnel; Resolution; Resources; Source; Sulfur Amino Acids; United States National Institutes of Health; Variant; design; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objectives of this research are to evaluate toxicological perturbations of metabolism due to complex chemical mixtures and diet-chemical interactions using high resolution 1H-NMR spectroscopy. These experiments are designed to provide data on the extent of normal variation in metabolic profiles within healthy individuals and, in combination with key glutathione redox measurements, will show whether changes due to chemical exposure and diet can be discriminated.

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