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Molecular mechanisms underlying induction of Haematopoietic Stem cells in the embryo

Molecular mechanisms underlying induction of Haematopoietic Stem cells in the embryo
胚胎中造血干细胞诱导的分子机制
批准号:
nhmrc : 1081933
负责人:
Prof Graham Lieschke
金额:
$38.51万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2017-12-31

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中文摘要
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英文摘要
Hematopoiesis, the processes of making blood cells, represents one of the best-defined paradigms for studying stem cell biology, but our understanding of how theses cells form in the embryo is incomplete.Our preliminary studies have revealed the existence of a novel "buddy cell" that directly regulates the induction of blood stem cells. This grant seeks to further these observations, and its general aim is to identify the molecular signals that the buddy cell uses to make blood stem cells
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