Center For Education and Research in Therapeutics

治疗学教育与研究中心

• 批准号: 7898829
• 负责人: BRIAN LESLIE STROM
• 金额: $ 97.63万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7898829
• 关键词: Center; Education; Research; Therapeutics

DESCRIPTION (Provided by the Applicant): The University of Pennsylvania Center for Education and Research on Therapeutics (PennCERT) proposes to reinforce and expand its infrastructure, while conducting research and educational programs to advance therapeutics in an even more focused way. The theme of the PennCERT will continue to be infectious diseases (anti-infective therapy) with the following new subthemes (i.e., areas of methodologic focus where we can be a resource for the whole CERT network): 1) pharmacoepidemiology, 2) patient safety, and 3) health information technology. In particular, we propose to: 1. Build on and enhance our research and educational center with its coordinated infrastructure; continue our active participation in the national CERTs program; continue our mini-grant program that funds studies addressing relevant therapeutic questions and pilot studies that support the development of R01 applications; and maintain an impressive series of data resources, accessible to investigators from the PennCERT and other CERTs. 2. Conduct research to improve the underlying evidence base for decisions about the use and effects of anti-infectives. 3. Implement and evaluate interventions aimed at improving the use of anti-infectives in outpatient and especially inpatient settings, locally, regionally, and nationally. 4. Conduct education in research methods, critical appraisal of the medical literature, and therapeutic decisionmaking targeting multiple audiences, including medical students, graduate medical trainees, and health care professionals. 5. Disseminate and translate the results of our work, including publications and presentations: i) for the scientific/professional community; ii) the FDA, AHRQ, other CERTs, etc.; and iii) the public, building on the well-developed dissemination program of the Leonard Davis Institute. New features of the current PennCERT application include new investigators (former PennCERT trainees who have now accepted positions as faculty); investigators added to strengthen our expertise in health economics, biomedical informatics, and spatial modeling; an increased focus on pediatrics, with faculty and a major project planned at Children's Hospital of Philadelphia; an increased focus on research and education intended to develop, implement, and evaluate novel programs for translating evidence on optimal antimicrobial drug practices into everyday practice, particularly in hospital settings; four larger research projects, possible because of the increased resources now available; and an increased flexibility in choice of projects in future years, as earlier projects are completed.

描述（由申请人提供）：宾夕法尼亚大学治疗学教育与研究中心（Penncert）提议加强和扩展其基础设施，同时进行研究和教育计划，以更加集中的方式推进治疗剂。 Penncert的主题将继续是传染病（抗感染疗法），其新的子主题（即，方法论重点领域，我们可以成为整个证书网络的资源）：1）药物ePIDEMIOLOGY，2）2）患者安全和3）健康信息技术。特别是，我们建议： 1。以其协调的基础设施为基础并增强我们的研究和教育中心；继续我们积极参与国家证书计划；继续我们的小型计划，该计划资助了有关支持R01应用程序开发的相关治疗问题和试点研究的研究；并保持一系列令人印象深刻的数据资源，可供Penncert和其他证书的调查人员访问。 2.进行研究以改善有关使用和影响的基本证据基础 反感染物。 3。实施和评估旨在改善门诊和使用反感染剂的干预措施 特别是在本地，地区和全国范围内的住院环境。 4。在研究方法中进行教育，医学文献的批判性评估和治疗 针对多个受众的决策，包括医学生，研究生医学培训人员， 和医疗保健专业人员。 5。传播和翻译我们的工作结果，包括出版物和演示：i） 科学/专业社区； ii）FDA，AHRQ，其他证书等； iii）公众，建立 伦纳德·戴维斯学院（Leonard Davis Institute）发达的传播计划。 当前的Penncert申请的新功能包括新的调查人员（前Penncert训练者，他们现在接受任职职位）；研究人员增加了为加强我们在健康经济学，生物医学信息学和空间建模方面的专业知识；对儿科的关注越来越多，教职员工和费城儿童医院计划的一个重大项目；旨在开发，实施和评估新的计划的研究和教育的重点越来越多，以将最佳抗菌药物实践的证据转化为日常实践，尤其是在医院环境中；四个较大的研究项目，由于现在可用的资源增加而可能；随着早期项目的完成，未来几年的项目选择的灵活性提高了。

项目成果

Public reporting of hospital-acquired infections is not associated with improved processes or outcomes.

公开报告医院获得性感染与改进流程或结果无关。

• DOI: 10.1086/671279
• 发表时间: 2013
• 期刊: Infection control and hospital epidemiology
• 影响因子: 4.5
• 作者: Linkin,DarrenR;Fishman,NeilO;Shea,JudyA;Yang,Wei;Cary,MarkS;Lautenbach,Ebbing
• 通讯作者: Lautenbach,Ebbing

The impact of household transmission on duration of outpatient colonization with methicillin-resistant Staphylococcus aureus.

• DOI: 10.1017/s0950268810000099
• 发表时间: 2010-05
• 期刊: EPIDEMIOLOGY AND INFECTION
• 影响因子: 4.2
• 作者: Lautenbach, E.;Tolomeo, P.;Nachamkin, I.;Hu, B.;Zaoutis, T. E.
• 通讯作者: Zaoutis, T. E.