Clinical Pharmacoepidemiology Training Grant

描述(由申请人提供)：宾夕法尼亚大学医学院(SOM)临床流行病学和生物统计中心(CCEB)与费城科学大学(USP)合作，提议开发一个创新的临床药物流行病学研究培训计划，专门为培训临床医生成为严格的、独立的学术调查人员，能够使用流行病学的一系列方法来研究药物在人群中的使用和效果。 培训计划的具体目的是：1)提供适用于临床药物流行病学研究的研究技术的深入知识；2)了解临床药理学的基本原理；3)为与临床药物流行病学相关的主题提供研究机会；4)在临床药物流行病学导师的指导下提供密集的研究经验；5)通过参加CCEB和USP的系列研讨会，将教职员工和研究员聚集在一起。学员将获得临床流行病学理学硕士学位，并有资格参加临床药理学委员会考试。 为期两到三年的培训计划包括：1)临床流行病学、研究方法学和生物统计学必修课的核心课程；2)药物流行病学和药代动力学的必修课；3)临床药理学的临床经验；4)药理学、药剂学实践或与学员兴趣和经验相关的其他领域的选修课；5)广泛的独立阅读资料；6)由资深方法学家/临床药物流行病学家、临床药理学家和生物统计学家提供指导；7)出席和参加美国临床药物流行病学委员会和USP的研究研讨会；以及8)完成临床药物流行病学的指导独立研究项目。 建议中的计划的优点是：1)CCEB成功的研究培训计划的悠久历史；2)向学员提供的全面的课程和研究计划；3)CCEB的国际知名的临床药物流行病学计划；4)USP提供的杰出药物培训计划；以及5)计划主任和教职员工广泛的成功培训记录。

DESCRIPTION (provided by applicant): The Center for Clinical Epidemiology and Biostatistics (CCEB) of the University of Pennsylvania School of Medicine (SOM), in collaboration with the University of the Sciences in Philadelphia (USP), proposes to develop an innovative research training program in clinical pharmacoepidemiology, specifically designed to train clinicians to be rigorous, independent academic investigators able to use the range of approaches available in epidemiology to study the use and effects of medications in populations. The specific aims of the training program are to: 1) provide in-depth knowledge of the research techniques appropriate to clinical pharmacoepidemiology research; 2) provide an understanding of the basic principles of clinical pharmacology; 3) provide opportunities for the study of topics related to clinical pharmacoepidemiology; 4) provide intensive, supervised research experience with mentors in clinical pharmacoepidemiology; and 5) bring together faculty and fellows through participation in seminar series in the CCEB and at USP. Trainees would earn a Master's of Science in Clinical Epidemiology (MSCE) degree and be eligible to sit for the Clinical Pharmacology Board exam. The two- to three-year training program consists of: 1) a core curriculum of required courses in clinical epidemiology, research methodology, and biostatistics; 2) required courses in pharmacoepidemiology and pharmacokinetics; 3) required clinical experiences in clinical pharmacology; 4) elective courses in pharmacology, pharmacy practice, or other areas relevant to the trainees' interests and experience; 5) extensive independent readings; 6) mentoring provided by senior methodologists/clinical pharmacoepidemiologists, clinical pharmacologists, and biostatisticians; 7) attendance at and participation in research seminars in the CCEB and at USP; and 8) the completion of a mentored independent research project in clinical pharmacoepidemiology. Strengths of the proposed program are: 1) the long history of successful research training programs in the CCEB; 2) the comprehensive course offerings and research programs that are available to trainees; 3) the internationally renowned clinical pharmacoepidemiology program housed in the CCEB; 4) the distinguished pharmaceutical training program offered by USP; and 5) the extensive successful training records of the program director and faculty.