Pilot Project Research Project 1

试点项目研究项目1

基本信息

  • 批准号:
    9332104
  • 负责人:
  • 金额:
    $ 4.04万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
  • 资助国家:
    美国
  • 起止时间:
  • 项目状态:
    未结题

项目摘要

ABSTRACT – PILOT RESEARCH PROJECT 1 (P1) Two SUNY medical campuses (SUNY Stony Brook and SUNY Downstate) serving underrepresented minority communities with cancer health disparities are partnering with the NCI designated Cancer Center at the Cold Spring Harbor Laboratories (CSHL) to evaluate biological and genetic differences in colorectal cancers that may link to differences in cancer incidence and outcome observed in racial and ethnic minorities. We plan to develop a SUNY Downstate GI BioBank that will greatly augment the representation of underrepresented minorities in the collection of biospecimens that will use the same standard operating procedures currently in place at the SUNY Stony Brook GI BioBank. Furthermore the clinical metadata elements collected at SUNY Downstate will be the same and utilize a common controlled vocabulary that is used by the SUNY Stony Brook GI BioBank. To increase community participatory research among racial and ethnic minority populations, we plan to leverage the resources and expertise of the SUNY Downstate Brooklyn Health Disparities Center (led by Dr. Moro Salifu) in developing community education and outreach programs in underserved communities with a high proportion of racial and ethnic minorities (>70% African Americans). In P1, we propose to generate genomic and epigenetic profiling data of colon cancers using the NCI supported CSHL Shared DNA Resource Core directed by Dr. Dick McCombie (CSHL contact PI for P1) Generating the sequencing data will provide immediate feedback to the Downstate GI BioBank with respect to monitoring Q/A for their collection efforts. This genomic and epigenomic data will be linkable to parallel microarray and RNA-Seq data generated on the same coded deidentified samples by Dr. Jennie Williams (SUNY contact PI for P1). We anticipate that making the linked datasets available on the integrated biomedical informatics platform being developed by this proposed P20 project will facilitate sharing of these extremely valuable datasets with the larger cancer research community.
摘要-试点研究项目1 (p1)

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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ELLEN LI其他文献

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{{ truncateString('ELLEN LI', 18)}}的其他基金

1/2: Partnership to study racial/ethnic differences in GI cancer biology
1/2:合作研究胃肠道癌症生物学中的种族/民族差异
  • 批准号:
    9332092
  • 财政年份:
    2015
  • 资助金额:
    $ 4.04万
  • 项目类别:
1/2: Partnership to study racial/ethnic differences in GI cancer biology
1/2:合作研究胃肠道癌症生物学中的种族/民族差异
  • 批准号:
    9148200
  • 财政年份:
    2015
  • 资助金额:
    $ 4.04万
  • 项目类别:
1/2: Partnership to study racial/ethnic differences in GI cancer biology
1/2:合作研究胃肠道癌症生物学中的种族/民族差异
  • 批准号:
    9330994
  • 财政年份:
    2015
  • 资助金额:
    $ 4.04万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    9038105
  • 财政年份:
    2015
  • 资助金额:
    $ 4.04万
  • 项目类别:
1/2: Partnership to study racial/ethnic differences in GI cancer biology
1/2:合作研究胃肠道癌症生物学中的种族/民族差异
  • 批准号:
    9379097
  • 财政年份:
    2015
  • 资助金额:
    $ 4.04万
  • 项目类别:
Effect of Crohn's Disease Risk Alleles on Enteric Microbiota
克罗恩病风险等位基因对肠道微生物群的影响
  • 批准号:
    8147921
  • 财政年份:
    2009
  • 资助金额:
    $ 4.04万
  • 项目类别:
Effect of Crohn's Disease Risk Alleles on Enteric Microbiota
克罗恩病风险等位基因对肠道微生物群的影响
  • 批准号:
    7647008
  • 财政年份:
    2009
  • 资助金额:
    $ 4.04万
  • 项目类别:
RESEARCH BASE AND PROGRESS
研究基础及进展
  • 批准号:
    7767530
  • 财政年份:
    2009
  • 资助金额:
    $ 4.04万
  • 项目类别:
Trans-NDDK Short-term Training for Medical Students
Trans-NDDK医学生短期培训
  • 批准号:
    7409163
  • 财政年份:
    2006
  • 资助金额:
    $ 4.04万
  • 项目类别:
Trans-NDDK Short-term Training for Medical Students
Trans-NDDK医学生短期培训
  • 批准号:
    7067749
  • 财政年份:
    2006
  • 资助金额:
    $ 4.04万
  • 项目类别:

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