Duke Environmental Analysis Laboratory

杜克大学环境分析实验室

• 批准号: 9814448
• 负责人: P. Lee Ferguson
• 金额: $ 100万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9814448
• 关键词: Administrative Coordination; Aromatic Polycyclic Hydrocarbons; Biological; Chemical Exposure; Chemicals; Chronic Disease; Collaborations; Community Health; Consultations; Core Facility; Data; Development; Devices; Dust; Environment; Environmental Exposure; Environmental Health; Environmental Impact; Environmental Pollution; Epidemiologist; Experimental Designs; Exposure to; Flame Retardants; Funding; Future; Health; Human; Individual; Infrastructure; Intervention; Knowledge; Laboratories; Laboratory Research; Leadership; Link; Mass Spectrum Analysis; Measurement; Measures; Methods; Office of Administrative Management; Outcome; Pesticides; Populations at Risk; Preparation; Quality of life; Recording of previous events; Research; Research Personnel; Research Support; Resolution; Resources; Risk; Sampling; Science; Scientist; Services; Silicones; Soil; Technical Expertise; Technology; Time; Trace metal; Training; United States National Institutes of Health; Universities; Water; air monitoring; analytical method; chemical threat; disorder risk; epidemiology study; experience; exposed human population; exposure pathway; improved; innovation; interest; laboratory development; new technology; novel strategies; persistent organic pollutants; phthalates; pollutant; programs; research study; risk mitigation; sample collection; screening; tool

The purpose of the Duke Environmental Analysis Laboratory (DEAL) Hub is to offer a comprehensive suite of analytical services to support epidemiologists and health researchers conducting studies focusing on the impact of environmental exposures on human health. This research is vital to understanding the links between chemical exposures and human health endpoints, knowledge which is essential in mitigating disease risk and improving quality of life. DEAL will be co-directed by Dr. Heather Stapleton, a trained environmental chemist and exposure scientist, and Dr. Lee Ferguson, a trained mass spectrometrist and environmental analytical chemist. Drs. Stapleton and Ferguson each have over 20 years of experience using mass spectrometry to detect and quantify contaminants in environmental samples and are pioneers in the fields of emerging contaminants, exposure science, and non-targeted analytical methods. The long-term objectives of the DEAL Hub are to: 1) provide consultation and advice to environmental health researchers to support human health studies ; 2) provide comprehensive and state-of-the-art analytical services to supporting environmental health research; and 3) develop new analytical methods for the quantitation of emerging contaminants of interest to environmental health community and develop new technologies and tools for characterizing the exposome. To meet these objectives, DEAL consists of three internal cores. The first is the Environmental Sample Analysis Core (ESAR) that will support exposomic researchers by providing services for project consultations, sample preparation, extraction, and quantitative analysis of contaminants in environmental media using three distinct sample laboratories, the Targeted Organic, Targeted Inorganic, and Untargeted Organic labs. Through these three Labs, ESAR and DEAL as a whole can provide comprehensive services for a wide variety of analytes and support a larger breadth of environmental health researchers. Second is the Developmental Core that will create new analytical methods for the quantitation of emerging contaminants and develop new technologies and tools for characterizing the exposome. Finally, the Deal Hub will provide administrative management and coordination with the ESAR and Developmental Cores through the Administrative Core. This Administrative Core will also serve as the liaison between the DEAL Hub and the broader HHEAR Network, with Dr. Heather Stapleton as its Director. The intense collaboration of ESAR, Developmental, and Administrative Cores of the DEAL Hub will facilitate more and higher quality exposomic research that is essential for continued understanding of risk mitigation and environmental health interventions in at-risk populations.

杜克环境分析实验室(Deal)中心的目的是提供一套全面的 提供分析服务，以支持流行病学家和卫生研究人员进行侧重于 环境暴露对人类健康的影响。这项研究对于理解两者之间的联系至关重要 化学品暴露与人类健康终点、减少疾病风险所必需的知识 提高生活质量。Deal将由训练有素的环境化学家希瑟·斯台普顿博士共同执导 以及李·弗格森博士，他是一名训练有素的质谱学家和环境分析专家 化学家。斯台普顿博士和弗格森博士都有超过20年的使用质谱学的经验 检测和量化环境样品中的污染物，是新兴领域的先驱 污染物、暴露科学和非目标分析方法。这笔交易的长期目标 中心是：1)向环境健康研究人员提供咨询和建议，以支持人类健康 研究；2)提供全面和最先进的分析服务，以支持环境健康 研究；以及3)开发新的分析方法，以量化新出现的 环境卫生社区，并开发新的技术和工具来确定暴露组的特征。至 要达到这些目标，Deal由三个内部核心组成。一是环境样品分析 核心(ESAR)，将通过为项目咨询提供服务来支持曝光研究人员，样本 环境介质中污染物的制备、提取和定量分析 样品实验室，靶向有机、靶向无机和非靶向有机实验室。通过这些 三个实验室、Esar和Deal作为一个整体可以为各种分析物提供全面的服务 并支持更广泛的环境健康研究人员。二是发展核心，将 创造新的分析方法对新出现的污染物进行量化，并开发新技术 以及用于表征曝光组的工具。最后，交易中心将提供行政管理和 通过行政核心与ESAR和发展核心进行协调。此管理 CORE还将担任Deal Hub和更广泛的HHEAR网络之间的联络人，Heather博士 斯台普顿担任董事。ESAR、开发和管理核心的紧密合作 交易中心将促进更多、更高质量的暴露研究，这对继续 对高危人群的风险缓解和环境卫生干预的了解。