Duke Environmental Analysis Laboratory

杜克大学环境分析实验室

• 批准号: 10015280
• 负责人: P. Lee Ferguson
• 金额: $ 100万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10015280
• 关键词: Administrative Coordination; Aromatic Polycyclic Hydrocarbons; Biological; Chemical Exposure; Chemicals; Chronic Disease; Collaborations; Community Health; Consultations; Core Facility; Data; Development; Devices; Dust; Environment; Environmental Exposure; Environmental Health; Environmental Impact; Environmental Pollution; Epidemiologist; Experimental Designs; Exposure to; Flame Retardants; Funding; Future; Health; Human; Individual; Infrastructure; Intervention; Knowledge; Laboratories; Laboratory Research; Leadership; Link; Mass Spectrum Analysis; Measurement; Measures; Methods; Office of Administrative Management; Outcome; Pesticides; Populations at Risk; Preparation; Quality of life; Recording of previous events; Research; Research Personnel; Research Support; Resolution; Resources; Risk; Sampling; Science; Scientist; Services; Silicones; Soil; Technical Expertise; Technology; Time; Trace metal; Training; United States National Institutes of Health; Universities; Water; air monitoring; analytical method; chemical threat; data exchange; disorder risk; epidemiology study; experience; exposed human population; exposure pathway; improved; innovation; interest; laboratory development; new technology; novel strategies; persistent organic pollutants; phthalates; pollutant; programs; research study; risk mitigation; sample collection; screening; tool

The purpose of the Duke Environmental Analysis Laboratory (DEAL) Hub is to offer a comprehensive suite of analytical services to support epidemiologists and health researchers conducting studies focusing on the impact of environmental exposures on human health. This research is vital to understanding the links between chemical exposures and human health endpoints, knowledge which is essential in mitigating disease risk and improving quality of life. DEAL will be co-directed by Dr. Heather Stapleton, a trained environmental chemist and exposure scientist, and Dr. Lee Ferguson, a trained mass spectrometrist and environmental analytical chemist. Drs. Stapleton and Ferguson each have over 20 years of experience using mass spectrometry to detect and quantify contaminants in environmental samples and are pioneers in the fields of emerging contaminants, exposure science, and non-targeted analytical methods. The long-term objectives of the DEAL Hub are to: 1) provide consultation and advice to environmental health researchers to support human health studies ; 2) provide comprehensive and state-of-the-art analytical services to supporting environmental health research; and 3) develop new analytical methods for the quantitation of emerging contaminants of interest to environmental health community and develop new technologies and tools for characterizing the exposome. To meet these objectives, DEAL consists of three internal cores. The first is the Environmental Sample Analysis Core (ESAR) that will support exposomic researchers by providing services for project consultations, sample preparation, extraction, and quantitative analysis of contaminants in environmental media using three distinct sample laboratories, the Targeted Organic, Targeted Inorganic, and Untargeted Organic labs. Through these three Labs, ESAR and DEAL as a whole can provide comprehensive services for a wide variety of analytes and support a larger breadth of environmental health researchers. Second is the Developmental Core that will create new analytical methods for the quantitation of emerging contaminants and develop new technologies and tools for characterizing the exposome. Finally, the Deal Hub will provide administrative management and coordination with the ESAR and Developmental Cores through the Administrative Core. This Administrative Core will also serve as the liaison between the DEAL Hub and the broader HHEAR Network, with Dr. Heather Stapleton as its Director. The intense collaboration of ESAR, Developmental, and Administrative Cores of the DEAL Hub will facilitate more and higher quality exposomic research that is essential for continued understanding of risk mitigation and environmental health interventions in at-risk populations.

杜克环境分析实验室（DEAL）中心的目的是提供一套全面的 分析服务，以支持流行病学家和卫生研究人员进行研究，重点是 环境暴露对人类健康的影响。这项研究对于理解 化学品接触和人类健康终点，对减轻疾病风险至关重要的知识， 提高生活质量。DEAL将由石楠斯台普顿博士共同指导，他是一位训练有素的环境化学家 和曝光科学家，以及李弗格森博士，一个训练有素的质谱仪和环境分析 化学家斯台普顿博士和弗格森博士都有超过20年的使用质谱法的经验， 检测和量化环境样品中的污染物，是新兴领域的先驱。 污染物、暴露科学和非靶向分析方法。Deal的长期目标 中心的任务是：1）为环境健康研究人员提供咨询和建议，以支持人类健康 研究; 2）提供全面和最先进的分析服务，以支持环境健康 研究;和3）开发新的分析方法，用于定量新出现的感兴趣的污染物， 环境健康社区和开发新的技术和工具，表征麻烦。到 为了实现这些目标，DEAL由三个内部核心组成。一是环境样品分析 核心（ESAR）将通过提供项目咨询服务， 使用三种不同的方法制备、提取和定量分析环境介质中的污染物 样品实验室，目标有机，目标无机和非目标有机实验室。通过这些 三个实验室，ESAR和DEAL作为一个整体可以为各种分析物提供全面的服务 并支持更广泛的环境健康研究人员。第二个是发展核心， 创建新的分析方法来定量新兴污染物并开发新技术 和描述麻烦的工具。最后，Deal Hub将提供行政管理， 通过行政核心与ESAR和发展核心协调。这一行政 Core还将与石楠博士一起担任DEAL Hub和更广泛的HHEAR网络之间的联络人 斯台普顿担任其主任。ESAR、发展和行政核心的密切合作 DEAL Hub将促进更多和更高质量的生物学研究，这对持续发展至关重要。 了解风险缓解和对高危人群的环境卫生干预措施。