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Center for Biomedical OCT Research and Translation

生物医学OCT研究与转化中心

基本信息

批准号：
9521706
负责人：
Brett E Bouma
金额：
$ 17.1万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-30 至 2018-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9521706
关键词：
Acoustics Address Adoption Algorithms Angiography Animal Disease Models Area Biological Biology Biomechanics Biomedical Research Biomedical Technology Blood capillaries Blood flow Caliber Characteristics Clinical Clinical Research Collaborations Communication Communities Complex Computer software Computers and Advanced Instrumentation Cornea Cystic Fibrosis Data Data Analyses Diagnosis Diagnostic Disease Disease Progression Drug Targeting Early Diagnosis Educational workshop Engineering Ferrets Fiber Optics Formulation Fostering Functional Imaging Funding Gastrointestinal Endoscopy Geographic Distribution Goals Hand Image Imagery Imaging Device Imaging technology Individual Industrialization Inflammation Instruction International Internet Investigation Knowledge Lead Lymphatic Measures Medical Medical Imaging Medicine Methods Microscope Mission Modeling Mucociliary Clearance Mus Optical Coherence Tomography Optics Organ Peripheral Nerves Pilot Projects Property Publications Recruitment Activity Research Research Personnel Resolution Resources Respiratory physiology Rewards Rotation Scanning Scientist Services Site Speed Stress Technology Tissue imaging Tissues Training Training Programs Translations Work base biological research capillary clinical Diagnosis clinical imaging clinical research site commercialization contrast imaging design disease diagnosis elastography experience experimental study flexibility frontier image processing imaging system improved in vivo imaging innovation insight instrument instrumentation interstitial microscopic imaging novel therapeutic intervention operation post-doctoral training pre-clinical pre-doctoral public health relevance research and development response sound symposium tool vibration viscoelasticity

项目摘要

DESCRIPTION (provided by applicant): Overall the Center for Biomedical OCT Research and Translation seeks to push the technological frontier of optical coherence tomography instrumentation and methods in response to challenges in biology and medicine. Fundamental to our approach, CBORT thrives on an intimate, push-pull relationship between physicists/engineers and biological, pre-clinical and clinical scientists. The most direct impact o the Resource will be to develop and provide broad access to powerful new tools for biological and clinical research. Facilitating rapid, high-resolution, high-contrast imaging through tailored, application-specific instruments will accelerate and open new avenues of biomedical research. Results of this effort may include, for example, the identification of new methods for diagnosis, new insights into disease or disease progression, or the formulation of new therapeutic strategies or drug targets. Further, we anticipate that some of the resulting biological and clinicl research will identify new opportunities for commercialization of technology. By developing and making innovative and effective OCT technology available, we anticipate that there will be rapid progress and significant advances in each of these areas. Training and dissemination of OCT instruments and methods is another priority of CBORT. Regular symposia and workshops foster a broader communication within the field, provide access to results of research, and offer a hand-on experience with the construction, operation, and interpretation of data from state-of-the-art imaging systems. External users additionally have access to imaging systems within the Resource to conduct focused experiments or to generate preliminary data. CBORT can also place imaging systems off-site for clinical or pre-clinical pilot studies.