Center for Biomedical OCT Research and Translation

项目概要： 一般来说，阿尔蒂人工智能和机器学习， 医学成像的潜力。我们生物医学OCT研究中心的多个项目 包括机器学习算法的开发和训练， 解释，量化和改善OCT。通过P41支持，我们以前 与麻省理工学院计算机科学教授Polina Golland建立了合作关系， 我和她一起指导一位博士后。我们最近采访了 候选人填补这一奖学金，并将使用补充资金，使在一个新的研究员， 我们在这一重要的技术领域保持进展，这是多个TRD的基础 项目此外，我们将通过加强我们的 网站和新的社交媒体渠道。最后，我们将保持重要的近期 在高重复率波长扫描的开发中已经取得的进展 激光通过外部供应商，我们开发了高性能啁啾周期光纤， 布拉格光栅。重要的是要保持这一项目的势头，因为激光 发展将使多个不同的TRD项目。 相关性： 生物医学OCT研究和翻译中心在 开发新的成像技术、仪器和应用。我们的几 这些项目导致了改善医疗保健的商业医疗设备。我们也一直 非常成功的服务项目，使先进的成像仪器可用 在我们的中心和远程研究环境中广泛的合作者。 在一个过渡年中保持这些核心业务将使我们的项目得以继续 在我们下一个竞争性资助周期中不减速。

Project Summary: Artificial intelligence in general and machine learning specifically, represent tremendous potential for medical imaging. Multiple projects within our Center for Biomedical OCT Research and Translation include the development and training of machine learning algorithms for interpreting, quantifying, and improving OCT. Through P41 support, we have previously established a collaboration with MIT Computer Science Professor Polina Golland and presently co-mentor a post-doctoral fellow with her. We have recently conducted interviews with candidates to fill this fellowship and will use supplemental funding to bring in a new fellow so that we maintain progress in this important technical area, which underpins multiple TRD projects. In addition, we will expand on our dissemination efforts through enhancements to our website and through new social media channels. Finally, we will maintain important recent progress that has been made in the development of high repetition rate wavelength swept lasers. Through an external vendor, we have developed high performance, chirped period fiber Bragg gratings. It is important to maintain the momentum of this project as the laser developments will enable multiple different TRD projects. Relevance: The Center for Biomedical OCT Research and Translation has been highly productive in the development of novel imaging technologies, instruments, and applications. Several of our projects have led to commercial medical devices that improve health care. We have also been very successful in service projects that have made sophisticated imaging instruments available to a wide spectrum of collaborators in our Center and also in remote research settings. Maintaining these core efforts through an interim year will permit our programs to continue without deceleration in our next competitive grant cycle.