Administrative and Resource Core

项目概要ARAC WU-DDRCC的首要使命是促进合作，多学科研究，重点是 消化系统疾病中宿主与环境的相互作用行政和资源的目标 接入核心（ARAC）将协调、管理和整合WU-DDRCC的所有活动， 最大限度地提高我们的会员从所有核心和丰富计划的价值。这些目标将会实现 通过：（1）调整核心服务和技术，以反映我们研究基地的主题兴趣; (2)通过丰富计划促进消化系统疾病的多学科合作研究 定期研讨会，访问演讲者，期刊俱乐部，专题讨论会和小型休假;（3）培养年轻人 通过试点和可行性（P/F）奖励促进科学独立性的教师职业发展： (4)促进当地其他NIDDK资助中心之间的协作和协同互动（刚果民主共和国， NORC）和整个地区的其他DDRCC（中西部联盟）。ARAC通过以下方式实现这些目标： 提供科学核心的稳定、反应迅速的管理、全球财务监督和战略分配， 补充奖励，以利用机构核心。这些目标由内部（IAB）和外部 咨询委员会（EAB）。自2013年以来的主要成就包括：（1）调整成员资格， 不断变化的利益和离职与新的招聘相平衡（2018年12月50名正式成员vs 49名正式成员 （2）通过以下方式实现对成员的支持： 年度直接成本（ADC）净增长30%（2013年12月2380万美元，2018年12月3090万美元）。(3)核心的演变 服务，以应对新的机构投资，最值得注意的是新的精密动物模型和类器官 核心（PAMOC），（4）投资于P/F获奖者，自2013年以来投资回报率为26：1，并推出 研究学术生涯（95%的获奖者从1999年到2000年仍然活跃在消化系统疾病研究领域） （5）赞助一个每年约有12位外部演讲者（包括至少一位 指定的代表性不足的少数群体/年），一个正式的指导方案。 ARAC是：（1）为成员提供领导，治理和行政基础设施，包括 核心服务与研究基地当前和未来需求的战略一致性。(2)管理和 监督核心服务，以确保在内部执行人员的指导下，及时提供高质量的专业知识 委员会（IEC）和内部咨询委员会（IAB）。(3)审查研究基地成员资格， 主题兴趣，由IEC和主题项目负责人指导。(4)促进青少年科学独立 教师通过P/F计划由外部顾问委员会（EAB）谁审查和选择获奖者的指导。 (5)促进合作，新的科学举措，职业发展和多样性的认识，通过一个 动态浓缩方案。(6)确保与其他复员方案协调中心持续进行行政和科学对话 特别是那些在中西部联盟以及NIDDK DDRCC计划网站。

PROJECT SUMMARY ARAC The overarching mission of the WU-DDRCC is to promote collaborative, multidisciplinary research focused on interactions between host and environment in digestive disease. The goals of the Administrative and Resource Access Core (ARAC) are to coordinate, manage and integrate all activities of the WU-DDRCC, thereby maximizing value to our membership from all Cores and Enrichment Programs. These goals will be accomplished by: (1) Aligning Core services and technologies to reflect thematic interests of our Research Base; (2) Promoting multidisciplinary, collaborative research in digestive disease through an Enrichment Program of regular seminars, visiting speakers, journal clubs, symposia and mini-sabbaticals; (3) Nurturing junior faculty career development via Pilot and Feasibility (P/F) Awards that facilitate scientific independence: (4) Catalyzing collaborative and synergistic interaction among other NIDDK funded Centers locally (DRC, NORC) and other DDRCCs throughout the region (Midwest Alliance). The ARAC pursues these goals by providing stable, responsive stewardship of scientific Cores, global financial oversight and strategic allocation of supplemental awards to leverage institutional Cores. These goals are guided by both Internal (IAB), and External Advisory Boards (EAB). KEY ACCOMPLISHMENTS since 2013 include: (1) Alignment of membership reflecting evolving interests and departures balanced with new recruitment (50 Full members 12/2018 vs 49 Full members 12/2013), with 50% of the current membership new since 2013, (2) Support of membership realized through 30% net growth in Annual Direct Costs (ADC) ($23.8M 12/2013 vs $30.9M 12/2018). (3) Evolution of Core services in response to new institutional investment, most notably a new Precision Animal Models and Organoids Core (PAMOC), (4) Investing in P/F Awardees, resulting in a 26:1 return on investment since 2013 and launching academic careers in research (95% still active in digestive disease research among awardees from 1999 to present), (5) Sponsoring an Enrichment Program featuring ~12 external speakers/year (including at least one designated underrepresented minority/year), a formal mentorship program THE SPECIFIC AIMS FOR THE ARAC ARE: (1) Provide leadership, governance and administrative infrastructure for members, including strategic alignment of Core services with current and future needs of the Research Base. (2) Manage and oversee Core services to assure timely, high quality, specialized expertise, guided by an Internal Executive Committee (IEC) and an Internal Advisory Board (IAB). (3) Review Research Base membership and align thematic interests, guided by IEC and Thematic Program Leaders. (4) Promote scientific independence for junior faculty through a P/F Program guided by an External Advisory Board (EAB) who review and select Awardees. (5) Promote collaboration, awareness of new scientific initiatives, career development and diversity through a dynamic Enrichment Program. (6) Assure continued administrative and scientific dialog with other DDRCCs particularly those in the Midwest Alliance as well as the NIDDK DDRCC program website.