Research Training Program in Vision Science

描述（由申请人提供）：由 12 名高级和中级研究人员组成的导师小组，包括 2 名新研究人员，每一位都具有研究培训经验，并参与过积极且有竞争力的研究项目，提议在威斯康星医学院 (MCW) 继续开展视觉科学研究培训项目 5 年。要求每年招收 5 名博士前培训生。目标仍然是让学员为眼科和视觉研究领域的研究职业做好准备。这要求学生对视觉系统的主要特征有广泛的、多学科的认识，对影响视力的疾病有当代的理解，以及视觉系统实验工作的现代研究技能和技术。它还要求学员获得在多学科研究环境中发挥作用所需的分析和沟通技能。导师小组提供视觉系统多个方面的经验，包括基本感光生物学、视网膜电路及其发育、眼前节的遗传学和疾病，以及包括电子顺磁共振波谱（EPR）、眼相干断层扫描（OCT）和自适应光学在内的重要技术。本次更新项目的新特​​点包括通过新的 MCW 基础和转化研究研究生项目强调转化研究，以及通过最近的招聘扩大 MCW 在 OCT 和自适应光学方面的能力，加强对现代成像技术的关注。博士前培训生将完成分子遗传学、生物化学、细胞生物学和神经生物学的核心课程，以及“科学伦理与诚信”和“视觉生物学”的必修课程，作为在项目教师的指导下进行论文研究的前奏。所有学生在进入导师实验室时都有机会参加基础和转化研究项目，其中包括转化研究方面的额外培训，以及论文至少一个具体目标具有转化性质的要求。导师实验室的所有学员还将参加每月一次的视觉科学研究论坛/期刊俱乐部、每月一次的视觉科学杰出讲座系列以及一年一度的视觉科学研讨会。

DESCRIPTION (provided by applicant): A mentor group of 12 senior and mid-level investigators and including with 2 new investigators, each with experience in research training and with active and competitive research programs, propose to continue a research Training Program in Vision Science at the Medical College of Wisconsin (MCW) for another 5 years. The request is for 5 pre-doctoral trainees annually. The goal remains to prepare trainees for research careers in ocular and vision research. This requires that students have a broad, multidisciplinary appreciation of the major features of the visual system, a contemporary understanding of the diseases that impact vision, and modern research skills and technologies for experimental work in the visual system. It also requires that trainees acquire the analytical and communication skills necessary to function in a multidisciplinary research environment. The mentor group provides experience in multiple facets of the visual system, including fundamental photoreceptor biology, retinal circuitry and its development, the genetics and diseases of the anterior segment, and important technology including electron paramagnetic resonance spectroscopy (EPR), ocular coherence tomography (OCT) and adaptive optics. New features of the program in this renewal include an emphasis on translational research via a new MCW graduate Program in Basic and Translational Research and an enhanced focus on modern imaging technology made possible by recent recruitments that expand MCW's capabilities in OCT and adaptive optics. Pre-doctoral trainees will complete a core curriculum of Molecular Genetics, Biochemistry, Cell Biology, and Neurobiology as well as required courses in "Ethics and Integrity in Science" and "The Biology of Vision" as a prelude to conducting dissertation research under the mentorship of a member of the program faculty. All students will have the opportunity at the time they enter a mentor laboratory to participate in Program in Basic and Translational Research, which includes additional training in translational research as well as a requirement for at least one Specific Aim of the dissertation to be translational in nature. All trainees in mentor labs will also participate in a monthly Research Forum/Journal Club in Vision Science, a monthly Distinguished Lecture Series in Vision Science, and an annual Vision Science Colloquium.