Research Training Program in Vision Science

描述（由申请人提供）：一个由12名高级和中级研究人员组成的导师小组，包括2名新研究人员，每名研究人员都有研究培训经验，并有积极和有竞争力的研究项目，建议在威斯康星医学院（MCW）继续进行视觉科学研究培训计划5年。每年招收5名博士预科生。目标仍然是为受训者在眼科和视觉研究方面的研究事业做好准备。这要求学生对视觉系统的主要特征有一个广泛的、多学科的认识，对影响视觉的疾病有一个当代的理解，以及对视觉系统实验工作的现代研究技能和技术。它还要求受训人员掌握在多学科研究环境中发挥作用所必需的分析和沟通技巧。导师小组在视觉系统的多个方面提供经验，包括基本的光感受器生物学，视网膜电路及其发育，遗传学和前段疾病，以及重要的技术，包括电子顺磁共振波谱（EPR），眼相干断层扫描（OCT）和自适应光学。此次更新项目的新特点包括通过新的MCW基础和转化研究研究生课程强调转化研究，以及通过最近的招聘扩大MCW在OCT和自适应光学方面的能力，加强对现代成像技术的关注。博士预科生将完成分子遗传学、生物化学、细胞生物学和神经生物学的核心课程，以及“科学中的伦理与诚信”和“视觉生物学”的必修课程，作为在项目教师指导下进行论文研究的序曲。所有学生在进入导师实验室时都有机会参加基础和转化研究项目，其中包括在转化研究方面的额外培训，以及至少一篇论文的特定目标是翻译性质的要求。所有导师实验室的学员还将参加每月一次的视觉科学研究论坛/期刊俱乐部，每月一次的视觉科学杰出系列讲座，以及每年一次的视觉科学研讨会。

DESCRIPTION (provided by applicant): A mentor group of 12 senior and mid-level investigators and including with 2 new investigators, each with experience in research training and with active and competitive research programs, propose to continue a research Training Program in Vision Science at the Medical College of Wisconsin (MCW) for another 5 years. The request is for 5 pre-doctoral trainees annually. The goal remains to prepare trainees for research careers in ocular and vision research. This requires that students have a broad, multidisciplinary appreciation of the major features of the visual system, a contemporary understanding of the diseases that impact vision, and modern research skills and technologies for experimental work in the visual system. It also requires that trainees acquire the analytical and communication skills necessary to function in a multidisciplinary research environment. The mentor group provides experience in multiple facets of the visual system, including fundamental photoreceptor biology, retinal circuitry and its development, the genetics and diseases of the anterior segment, and important technology including electron paramagnetic resonance spectroscopy (EPR), ocular coherence tomography (OCT) and adaptive optics. New features of the program in this renewal include an emphasis on translational research via a new MCW graduate Program in Basic and Translational Research and an enhanced focus on modern imaging technology made possible by recent recruitments that expand MCW's capabilities in OCT and adaptive optics. Pre-doctoral trainees will complete a core curriculum of Molecular Genetics, Biochemistry, Cell Biology, and Neurobiology as well as required courses in "Ethics and Integrity in Science" and "The Biology of Vision" as a prelude to conducting dissertation research under the mentorship of a member of the program faculty. All students will have the opportunity at the time they enter a mentor laboratory to participate in Program in Basic and Translational Research, which includes additional training in translational research as well as a requirement for at least one Specific Aim of the dissertation to be translational in nature. All trainees in mentor labs will also participate in a monthly Research Forum/Journal Club in Vision Science, a monthly Distinguished Lecture Series in Vision Science, and an annual Vision Science Colloquium.