NRSA Training Core

NRSA 培训核心

• 批准号: 10652659
• 负责人: Tamara Isakova
• 金额: $ 66.68万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652659
• 关键词: NRSA; Training; Core

PROJECT SUMMARY: TRAINING CORE This new U2C/TL1 application is responsive to calls for developing an innovative interdisciplinary training program to strengthen the Kidney, Urology Hematology (KUH) research workforce in order to address capacity building for KUH research. Chief obstacles to designing and implementing a successful interdisciplinary research training program include limitations in training assets, research and mentorship expertise, and opportunities for cross-disciplinary collaboration. To overcome these obstacles, the Training Core of the Chicago Kidney Urology Hematology network FOR city-Wide reseArch tRaining and career Development (Chicago KUH FORWARD) will train pre- and postdoctoral KUH trainees (10 slots/career stage; 20 slots total) across 6 institutions (Northwestern University (NU), Lurie Children’s Hospital at Chicago, University of Illinois at Chicago, University of Chicago, and Rush and Loyola Universities) in an innovative and integrated interdisciplinary training program that will converge on cross-cutting tools that can be utilized across diseases, fields, or questions. Unique features of the program will include adoption of general and specific competencies for interdisciplinary training, cross-disciplinary mentoring team, new cross-disciplinary curriculum that incorporates seminars, journal clubs and workshops that place emphasis on presentation of cross-cutting innovative tools and not specific diseases, dedicated grant writers groups, and a broad matrix of professional development activities that map to chosen competencies. The centerpiece of the Training Core is mentored cross-disciplinary research that yields scientific products. Resources provided by the Professional Development and Network Cores will synergize with the Training Core activities and augment career development of trainees. The operational hub for the Training Core will be the NU Division of Nephrology and Hypertension. Drs. Isakova, David, Thumbikat, and Eklund will co-lead the Training Core, and each brings unique and complementary expertise across KUH. Co-Directors and the Co-Investigators at Chicago KUH FORWARD institutions will constitute the Training Core Executive Committee, which will be assisted by a Diversity Committee and a Trainee Selection Committee. Administrative support will be provided by the Program Coordinator & Manager. The 75 Training Core mentors are KUH adult and pediatric specialists, and clinical, basic and translational researchers. The training program will be evaluated by an Evaluation Associate under the supervision of Dr. Drane, a training program evaluation expert. The Chicago KUH FORWARD Steering Committee will serve in internal advisory capacity, whereas the Chicago KUH FORWARD External Evaluation Board (EEB) will provide external review. The Training Core Executive Committee will work with the Diversity and Trainee Selection Committees to make changes to the program in response to the evaluation findings. Continuous cycles of evaluations and improvements will help us achieve our mission of making Chicago a national hub for innovative interdisciplinary KUH research training.

项目总结：培训核心 这一新的U2C/TL1应用程序响应了开发创新的跨学科培训的呼声 加强肾脏、泌尿外科血液学(KUH)研究队伍的计划，以解决能力问题 为KUH研究而建。设计和实施成功的跨学科的主要障碍 研究培训计划包括培训资产、研究和指导专业知识方面的限制，以及 提供跨学科协作的机会。为了克服这些障碍，培训的核心是 芝加哥肾脏泌尿系统血液学全市研究、培训和职业发展网络 (芝加哥前进)将培训博士后和博士后KUH实习生(每个职业阶段10个名额；总共20个名额) 涉及6个机构(西北大学(NU)、芝加哥鲁里儿童医院、伊利诺伊大学 芝加哥大学、芝加哥大学、拉什大学和洛约拉大学) 跨学科培训计划，将集中在可跨疾病使用的交叉工具上， 字段，或问题。该计划的独特之处将包括采用一般能力和具体能力 对于跨学科培训，跨学科指导团队，新的跨学科课程， 包括研讨会、期刊俱乐部和研讨会，重点放在横向介绍上 创新的工具，而不是特定的疾病，专注的赠款作者团体，以及广泛的专业矩阵 与所选能力相对应的开发活动。培训核心的核心是指导 产生科学产品的跨学科研究。专业人士提供的资源 开发和网络核心将与培训核心活动协同，并扩大职业生涯 实习生的发展。培训中心的业务中心将设在国立大学肾脏病学部。 高血压。Isakova博士、David博士、Thumbikat博士和埃克伦德博士将共同领导培训核心，每人带来 整个KUH的独特和互补的专业知识。芝加哥大学的联席董事和联合调查员 前沿机构将组成培训核心执行委员会，该委员会将由一个 多样性委员会和学员遴选委员会。行政支持将由 项目协调员兼经理。75名培训核心导师是KUH成人和儿科专家，以及 临床、基础和翻译研究人员。培训计划将通过评估进行评估 在培训项目评估专家Drane博士的监督下工作。《芝加哥邮报》 前导委员会将以内部咨询的身份提供服务，而芝加哥大学 前瞻外部评价委员会(EEB)将提供外部审查。培训核心管理人员 委员会将与多样性委员会和学员遴选委员会合作，在#年对计划进行修改 对评估结果的回应。持续循环的评估和改进将帮助我们实现 我们的使命是使芝加哥成为全国创新的跨学科KUH研究培训中心。

项目成果

Single-cell RNA-Seq identifies factors necessary for the regenerative phenotype of prostate luminal epithelial progenitors.

单细胞 RNA 测序可识别前列腺腔上皮祖细胞再生表型所需的因子。

• 发表时间: 2022
• 期刊: American journal of clinical and experimental urology
• 影响因子: 1.2
• 作者: Moline,DanielC;Zenner,MorganL;Burr,Alex;Vellky,JordanE;Nonn,Larisa;VanderGriend,DonaldJ
• 通讯作者: VanderGriend,DonaldJ