NRSA Training Core

NRSA 培训核心

• 批准号: 10652659
• 负责人: Tamara Isakova
• 金额: $ 66.68万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652659
• 关键词: NRSA; Training; Core

PROJECT SUMMARY: TRAINING CORE This new U2C/TL1 application is responsive to calls for developing an innovative interdisciplinary training program to strengthen the Kidney, Urology Hematology (KUH) research workforce in order to address capacity building for KUH research. Chief obstacles to designing and implementing a successful interdisciplinary research training program include limitations in training assets, research and mentorship expertise, and opportunities for cross-disciplinary collaboration. To overcome these obstacles, the Training Core of the Chicago Kidney Urology Hematology network FOR city-Wide reseArch tRaining and career Development (Chicago KUH FORWARD) will train pre- and postdoctoral KUH trainees (10 slots/career stage; 20 slots total) across 6 institutions (Northwestern University (NU), Lurie Children’s Hospital at Chicago, University of Illinois at Chicago, University of Chicago, and Rush and Loyola Universities) in an innovative and integrated interdisciplinary training program that will converge on cross-cutting tools that can be utilized across diseases, fields, or questions. Unique features of the program will include adoption of general and specific competencies for interdisciplinary training, cross-disciplinary mentoring team, new cross-disciplinary curriculum that incorporates seminars, journal clubs and workshops that place emphasis on presentation of cross-cutting innovative tools and not specific diseases, dedicated grant writers groups, and a broad matrix of professional development activities that map to chosen competencies. The centerpiece of the Training Core is mentored cross-disciplinary research that yields scientific products. Resources provided by the Professional Development and Network Cores will synergize with the Training Core activities and augment career development of trainees. The operational hub for the Training Core will be the NU Division of Nephrology and Hypertension. Drs. Isakova, David, Thumbikat, and Eklund will co-lead the Training Core, and each brings unique and complementary expertise across KUH. Co-Directors and the Co-Investigators at Chicago KUH FORWARD institutions will constitute the Training Core Executive Committee, which will be assisted by a Diversity Committee and a Trainee Selection Committee. Administrative support will be provided by the Program Coordinator & Manager. The 75 Training Core mentors are KUH adult and pediatric specialists, and clinical, basic and translational researchers. The training program will be evaluated by an Evaluation Associate under the supervision of Dr. Drane, a training program evaluation expert. The Chicago KUH FORWARD Steering Committee will serve in internal advisory capacity, whereas the Chicago KUH FORWARD External Evaluation Board (EEB) will provide external review. The Training Core Executive Committee will work with the Diversity and Trainee Selection Committees to make changes to the program in response to the evaluation findings. Continuous cycles of evaluations and improvements will help us achieve our mission of making Chicago a national hub for innovative interdisciplinary KUH research training.

项目摘要：培训核心 该新的U2C/TL1应用程序对开发创新跨学科培训的呼吁有响应 加强肾脏，泌尿科血液学（KUH）研究人员的计划，以解决能力 为Kuh研究建造。设计和实施成功的跨学科的主要障碍 研究培训计划包括培训资产，研究和指导专业知识的局限性，以及 跨学科合作的机会。为了克服这些障碍，训练核心 芝加哥肾脏泌尿科血液学网络，用于全市研究培训和职业发展 （芝加哥kuh前锋）将培训曾经和博士后KUH学员（10个老虎机/职业阶段；总计20个老虎机） 在6个机构（西北大学（NU），芝加哥的Lurie儿童医院，伊利诺伊大学 芝加哥，芝加哥大学以及拉什和洛约拉大学） 跨学科培训计划，该计划将收敛于可以在跨疾病中使用的横切工具， 字段或问题。该计划的独特功能将包括采用一般和特定能力 对于跨学科培训，跨学科指导团队，新的跨学科课程 纳入了重点介绍交叉切割的半小伙子，期刊俱乐部和研讨会 创新的工具，而不是特定疾病，专门的赠款作家群体以及广泛的专业矩阵 开发活动以选择能力。训练核心的核心被考虑 产生科学产品的跨学科研究。专业人士提供的资源 开发和网络核心将与培训核心活动和增强职业协同作用 成员的发展。培训核心的操作中心将是NU肾脏科和 高血压。博士。 Isakova，David，Thumbikat和Eklund将共同领导训练核心，每个核心都会带来 kuh的独特而完整的专业知识。芝加哥kuh的联合导演和共同投资者 远期机构将构成培训核心执行委员会，该委员会将由 多样性委员会和受训者选拔委员会。行政支持将由 计划协调员和经理。 75位培训核心导师是Kuh成人和儿科专家，以及 临床，基本和翻译研究人员。培训计划将通过评估进行评估 在培训计划评估专家Drane博士的监督下，合伙人。芝加哥库 前锋指导委员会将以内部咨询能力服务，而芝加哥kuh 远期外部评估委员会（EEB）将提供外部审查。培训核心主管 委员会将与多样性和受训者选拔委员会合作，以更改该计划 对评估结果的反应。评估和改进的持续循环将有助于我们实现 我们的使命是使芝加哥成为全国性的创新跨学科研究库。

项目成果

Single-cell RNA-Seq identifies factors necessary for the regenerative phenotype of prostate luminal epithelial progenitors.

单细胞 RNA 测序可识别前列腺腔上皮祖细胞再生表型所需的因子。

• 发表时间: 2022
• 期刊: American journal of clinical and experimental urology
• 影响因子: 1.2
• 作者: Moline,DanielC;Zenner,MorganL;Burr,Alex;Vellky,JordanE;Nonn,Larisa;VanderGriend,DonaldJ
• 通讯作者: VanderGriend,DonaldJ