NRSA Training Core

NRSA 培训核心

• 批准号: 10652659
• 负责人: Tamara Isakova
• 金额: $ 66.68万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652659
• 关键词: NRSA; Training; Core

PROJECT SUMMARY: TRAINING CORE This new U2C/TL1 application is responsive to calls for developing an innovative interdisciplinary training program to strengthen the Kidney, Urology Hematology (KUH) research workforce in order to address capacity building for KUH research. Chief obstacles to designing and implementing a successful interdisciplinary research training program include limitations in training assets, research and mentorship expertise, and opportunities for cross-disciplinary collaboration. To overcome these obstacles, the Training Core of the Chicago Kidney Urology Hematology network FOR city-Wide reseArch tRaining and career Development (Chicago KUH FORWARD) will train pre- and postdoctoral KUH trainees (10 slots/career stage; 20 slots total) across 6 institutions (Northwestern University (NU), Lurie Children’s Hospital at Chicago, University of Illinois at Chicago, University of Chicago, and Rush and Loyola Universities) in an innovative and integrated interdisciplinary training program that will converge on cross-cutting tools that can be utilized across diseases, fields, or questions. Unique features of the program will include adoption of general and specific competencies for interdisciplinary training, cross-disciplinary mentoring team, new cross-disciplinary curriculum that incorporates seminars, journal clubs and workshops that place emphasis on presentation of cross-cutting innovative tools and not specific diseases, dedicated grant writers groups, and a broad matrix of professional development activities that map to chosen competencies. The centerpiece of the Training Core is mentored cross-disciplinary research that yields scientific products. Resources provided by the Professional Development and Network Cores will synergize with the Training Core activities and augment career development of trainees. The operational hub for the Training Core will be the NU Division of Nephrology and Hypertension. Drs. Isakova, David, Thumbikat, and Eklund will co-lead the Training Core, and each brings unique and complementary expertise across KUH. Co-Directors and the Co-Investigators at Chicago KUH FORWARD institutions will constitute the Training Core Executive Committee, which will be assisted by a Diversity Committee and a Trainee Selection Committee. Administrative support will be provided by the Program Coordinator & Manager. The 75 Training Core mentors are KUH adult and pediatric specialists, and clinical, basic and translational researchers. The training program will be evaluated by an Evaluation Associate under the supervision of Dr. Drane, a training program evaluation expert. The Chicago KUH FORWARD Steering Committee will serve in internal advisory capacity, whereas the Chicago KUH FORWARD External Evaluation Board (EEB) will provide external review. The Training Core Executive Committee will work with the Diversity and Trainee Selection Committees to make changes to the program in response to the evaluation findings. Continuous cycles of evaluations and improvements will help us achieve our mission of making Chicago a national hub for innovative interdisciplinary KUH research training.

项目概要：培训核心 这个新的U2 C/TL 1应用程序是响应呼吁开发一个创新的跨学科培训 计划加强肾脏，泌尿血液学（KUH）的研究队伍，以解决能力 建筑为KUH研究。设计和实施成功的跨学科的主要障碍 研究培训计划包括培训资产、研究和指导专业知识的限制，以及 跨学科合作的机会。为了克服这些障碍， 芝加哥肾脏泌尿血液学网络为全市范围的研究 （芝加哥KUH前进）将培训博士前和博士后KUH学员（10个插槽/职业阶段;共20个插槽） 在6个机构（西北大学（NU），卢里儿童医院在芝加哥，伊利诺伊大学， 芝加哥，芝加哥大学，拉什和洛约拉大学）在一个创新和综合 跨学科培训计划，将集中在跨领域的工具，可用于各种疾病， 领域或问题。该计划的独特功能将包括通过一般和具体的能力 跨学科培训，跨学科辅导团队，新的跨学科课程， 包括研讨会、期刊俱乐部和讲习班，强调提出跨领域的 创新的工具，而不是特定的疾病，专门的赠款作家团体，以及广泛的专业矩阵 与所选能力相对应的发展活动。培训核心的核心是指导 跨学科的研究，产生科学产品。专业人员提供的资源 发展和网络核心将与培训核心活动协同作用，并增强职业生涯 学员的发展。培训核心的运营中心将是NU肾脏科， 高血压Isakova、大卫、Thumbikat和Eklund博士将共同领导培训核心， KUH的独特和互补的专业知识。芝加哥KUH的联合董事和联合研究者 FORWARD机构将组成培训核心执行委员会，该委员会将得到 多元化委员会和培训生选拔委员会。行政支持将由 项目协调员和经理。75名培训核心导师是KUH成人和儿科专家， 临床、基础和转化研究人员。培训计划将由评估小组进行评估。 在Drane博士的监督下，Drane博士是培训计划评估专家。芝加哥大学 FORWARD指导委员会将以内部顾问身份提供服务，而芝加哥KUH FORWARD外部评估委员会（EEB）将提供外部审查。培训核心执行官 委员会将与多元化和培训生选拔委员会合作， 对评价结果的回应。持续的评估和改进周期将帮助我们实现 我们的使命，使芝加哥创新跨学科KUH研究培训的国家中心。

项目成果

Single-cell RNA-Seq identifies factors necessary for the regenerative phenotype of prostate luminal epithelial progenitors.

单细胞 RNA 测序可识别前列腺腔上皮祖细胞再生表型所需的因子。

• 发表时间: 2022
• 期刊: American journal of clinical and experimental urology
• 影响因子: 1.2
• 作者: Moline,DanielC;Zenner,MorganL;Burr,Alex;Vellky,JordanE;Nonn,Larisa;VanderGriend,DonaldJ
• 通讯作者: VanderGriend,DonaldJ