Training Program in Basic Cancer Research

项目摘要 这个长期的“基础癌症研究培训计划”的总体目标是提供 我们的学员在生物医学癌症领域取得成功所需的基本技能 research.为了实现这一目标，我们为他们提供上级培训， 研究，结合医生和患者面临的临床挑战的深刻理解。到 为了实现这一目标，我们创建了一个独特的培训计划，现在进入第45个年头，名为 基础癌症研究培训计划（TP-BCR）。申请资助5名博士后 研究员和三名来自宾夕法尼亚大学佩雷尔曼医学院的博士前研究员， 生物医学研究生课程。位于宾夕法尼亚大学校园的中心， Wistar提供一流的研究环境，最近在最近的CCSG中被评为“卓越” 2018年更新。我们精心设计了一个培训计划，该计划结合了名为“长凳”的独特子计划， 到床边培训”和“科学企业家”计划，从而为我们的学员接触， 临床医生和癌症研究中的临床问题，对科学业务的独特见解， 知识产权，以及一个强大的课程，包括教学，写作和赠款研讨会 准备.我们的26名教师导师解决癌症的各种问题，大多数都有长期的 成功的培训记录，并且所有人都有充足的资金，平均890，000美元/年/导师（DC）。我们 目前的学员库由79名学员组成，其中包括24名博士前学员（13名TGE）和55名 博士后培训人员（20名TGE）。平均每个名额有四名TGE申请人，因此 使我们能够在这个项目中安排最合格的学员。所有插槽都已连续 填补了整个资助期间，我们的学员继续保持高生产力，与4.7手稿 在过去的三个周期中，平均每个学员有2篇第一作者手稿，98%的学员 继续从事研究相关或研究密集型职业。综合来看， 计划，这是唯一的T32集中在Wistar研究所，将提供基本技能 我们的学员在癌症研究中成功的独立职业生涯蓬勃发展。

Project Summary The overarching goal of this longstanding “Training Program in Basic Cancer Research” is to provide the fundamental skills necessary for our trainees to succeed in outstanding careers in biomedical cancer research. Toward that goal we provide them with superior training in the conduct of cutting edge research, combined with a deep appreciation of the clinical challenges that doctors and patients face. To achieve this goal, we have created a unique Training program, now entering its 45th year, entitled the Training Program in Basic Cancer Research (TP-BCR). Support is requested for five postdoctoral fellows, and three predoctoral fellows from the University of Pennsylvania Perelman School of Medicine, program in Biomedical Graduate Studies. Located at the heart of the University of Pennsylvania campus, Wistar offers a superb research environment, recently rated “Exceptional” at the most recent CCSG renewal in 2018. We have crafted a training program that combines unique sub-programs entitled “Bench to Bedside Training” and a “Science Entrepreneurs” program, thus offering our trainees exposure to clinicians and clinical problems in cancer research, unique insight into the business of science and intellectual property, and a robust curriculum that includes workshops in teaching, writing, and grant preparation. Our 26 faculty mentors tackle diverse questions in cancer, most have long-standing successful training records, and all are well-funded, with an average of $890,000/year/mentor (DC). Our current trainee pool consists of 79 trainees, which includes 24 predoctoral trainees (13 TGE) and 55 postdoctoral trainees (20 TGE). There is an average of four TGE applicants for each proffered slot, thus allowing us to place the most highly qualified trainees in this program. All slots have been continuously filled for the entire funding period, and our trainees continue to be highly productive, with 4.7 manuscripts and 2 first author manuscripts per trainee averaged in the past three cycles, and 98% of our trainees continuing in research-related or research-intensive careers. Taken together, this long-standing program, which is the only T32 centered at The Wistar Institute, will provide the fundamental skills necessary for our trainees to flourish in successful independent careers in cancer research.