Research Training in Pediatric Urology/CHB T32

小儿泌尿科研究培训/CHB T32

• 批准号: 10656495
• 负责人: Rosalyn M Adam
• 金额: $ 15.76万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10656495
• 关键词: Childhood; Research Training; Urology

Project Summary This is a competitive renewal application for a National Research Service Award (NRSA) Institutional Training grant (T32) for research training in pediatric urology at Boston Children's Hospital. For the past 14 years, this funding mechanism has supported the research component of our pediatric urology fellowship program. The pediatric urology fellowship at Boston Children's Hospital is the oldest and one of the most highly regarded such programs in the world. The Urology Department at BCH is one of the world's leading centers for pediatric urology and genitourinary reconstruction and has one of the largest research programs dedicated to basic urology research in the country. The overall goals of the training program are: (1) to teach state-of-the-art, hypothesis-driven, modern research methodology relevant to both basic science and clinical research; (2) to provide sufficient time and guidance for a mature postdoctoral experience in basic, translational or clinical studies relevant to the trainees' future clinical careers and academic leadership roles; (3) to provide trainees' with tangible skills in scientific writing, mentoring, personnel management and leadership to facilitate their transition to independent careers as clinician-scientists; and (4) to facilitate funding through career development and investigator-initiated grants. In the most recent funding cycle, postdoctoral MD trainees who have completed urology residency have conducted research in laboratory-based studies of urogenital tract development, physiology and pathophysiology. Training in clinical outcomes and health services research is also available in conjunction with faculty at the Harvard T.H. Chan School of Public Health. Trainees also undergo didactic training in critical thinking and grant writing, biostatistics and the responsible conduct of research. Two postdoctoral positions are requested per year for 2 years of research training. Twenty preceptors and 8 clinical preceptors comprising basic science and clinical faculty from 7 programs will support the training program. The fellowship represents a unique combination of outstanding basic, translational and clinical research training within one of the world's leading centers for academic medicine and biomedical science. It is designed to enable our graduates to establish their own competitive programs of scholarship and research during their careers as academic pediatric urologists. We anticipate these clinician-scientists will become leaders in academic urology through contributions to understanding the genitourinary system in fundamental terms, to translating basic research findings into clinical applications and to understanding the implications of new discoveries for patient care. The T32 Pediatric Urology Research Training mechanism is the major source of support for the fellows during the research component of their fellowship.

项目摘要 这是一个国家研究服务奖（NRSA）机构的竞争性续期申请 培训补助金（T32），用于波士顿儿童医院儿科泌尿学研究培训。过去14 多年来，这一资助机制一直支持我们的儿科泌尿学奖学金的研究部分 程序.波士顿儿童医院的儿科泌尿学奖学金是最古老的，也是最重要的之一。 在世界范围内，这样的节目受到高度评价。BCH的泌尿科是世界领先的 中心的小儿泌尿外科和泌尿生殖重建，并有一个最大的研究项目 致力于国内的基础泌尿学研究 培训计划的总体目标是：（1）教授最先进的，假设驱动的，现代的 基础科学和临床研究相关的研究方法;（2）提供足够的时间 和指导，在相关的基础，转化或临床研究的成熟博士后经验， （3）为学员提供实际技能， 科学写作，指导，人事管理和领导，以促进他们过渡到 作为临床科学家的独立职业;（4）通过职业发展促进资金， 发起人发起的赠款。在最近的资助周期，博士后MD学员谁拥有 完成泌尿外科住院医师已进行了以实验室为基础的泌尿生殖道研究 发育、生理学和病理生理学。临床结果和卫生服务研究培训 也可与哈佛T.H.陈氏公共卫生学院。受训人员还 接受批判性思维和赠款写作，生物统计学和负责任的行为的教学培训 research.每年要求两个博士后职位，为期2年的研究培训。二十 导师和8个临床导师组成的基础科学和临床教师从7个程序将 支持培训计划。 该奖学金代表了杰出的基础，转化和临床研究的独特组合 在世界领先的学术医学和生物医学科学中心之一接受培训。是 旨在使我们的毕业生建立自己的奖学金和研究的竞争力计划 在他们作为学术儿科泌尿科医生的职业生涯中。我们预计这些临床科学家将成为 学术泌尿学的领导者，通过对了解泌尿生殖系统的贡献， 基本术语，将基础研究成果转化为临床应用，并了解 新发现对患者护理的影响。T32小儿泌尿外科研究培训机制 是研究员在其研究金的研究部分期间的主要支助来源。

项目成果

Molecular mechanisms of esophageal epithelial regeneration following repair of surgical defects with acellular silk fibroin grafts.

• DOI: 10.1038/s41598-021-86511-9
• 发表时间: 2021-03-29
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Gundogdu G;Tosun M;Morhardt D;Gheinani AH;Algarrahi K;Yang X;Costa K;Alegria CG;Adam RM;Yang W;Mauney JR
• 通讯作者: Mauney JR

Beyond botulinum neurotoxin A for chemodenervation of the bladder.

• DOI: 10.1097/mou.0000000000000843
• 发表时间: 2021-03-01
• 期刊: Current opinion in urology
• 影响因子: 2.5
• 作者: Thaker H;Zhang S;Diamond DA;Dong M
• 通讯作者: Dong M

Parthenogenesis-derived multipotent stem cells adapted for tissue engineering applications.

孤雌生殖衍生的多能干细胞适用于组织工程应用。

• DOI: 10.1016/j.ymeth.2008.08.002
• 发表时间: 2009-02
• 期刊: METHODS
• 影响因子: 4.8
• 作者: Koh, Chester J.;Delo, Dawn M.;Lee, Jang Won;Siddiqui, M. Minhaj;Lanza, Robert P.;Soker, Shay;Yoo, James J.;Atala, Anthony
• 通讯作者: Atala, Anthony

Changes in Clinical Presentation and Renal Outcomes among Children with Febrile Urinary Tract Infection: 2005 vs 2015.

• DOI: 10.1097/ju.0000000000001597
• 发表时间: 2021-06
• 期刊: The Journal of urology
• 作者: Lee T;Varda BK;Venna A;McCarthy I;Logvinenko T;Nelson CP
• 通讯作者: Nelson CP

Enhanced Recovery After Surgery for an Uncommon Complex Urological Procedure: The Complete Primary Repair of Bladder Exstrophy.

罕见复杂泌尿外科手术术后加速康复：膀胱外翻的完全一期修复。

• DOI: 10.1097/ju.0000000000003593
• 发表时间: 2023
• 期刊: The Journal of urology
• 作者: Balthazar,AndreaK;Finkelstein,JuliaB;Williams,Vivian;Lee,Ted;Lajoie,Debra;Logvinenko,Tanya;Kim,Young-Jo;Chacko,Sabeena;Borer,JosephG;Lee,RichardS
• 通讯作者: Lee,RichardS