Pilot Project Program

拟议的P30第三阶段试点项目方案将主要作为一种机制，为以下试点研究提供资金 允许初级和高级调查人员生成初步数据，以便使用 核心中可用的独特技术。通过这一计划，我们希望鼓励使用我们的核心 使所有研究人员，特别是过去和现在的科布雷目标教员能够聚集在一起的技术 检验和发展新假说的初步数据。因此，我们预计将大大增加 赠款申请的竞争力，一旦获得资助，也可能需要未来使用核心资源。自.以来 这些项目在范围和需求上会有很大的不同，我们决定创建三种不同的渠道来资助试点 申请。SC BioCRAFT虎崽赠款(最高10000美元)：这些赠款将用于获取关键数据 提交一笔较大的(R类)赠款。已向外部提交拨款申请的调查人员 希望使用新数据修改申请的机构将优先获得此类奖项。SC BioCRAFT老虎奖助金(10K-50K美元)：这些奖助金将保留给高风险-高回报类型 提出在再生医学领域进行开创性研究的申请。这些可以是单一的 交点或多个交点方案。SC BioCRAFT Tiger Streak赠款：(50K-75K美元)。《老虎的目的》 Streak助学金计划是为建立或扩大多学科提供资金支持 协作，这将导致开发更具竞争力的中心型提案，并具有重要意义 协作性提案。可用于试点项目的资金总额为20万美元/年。代金券将用于 支付通过核心提供的服务的成本。代金券计划的年度预算为 4万美元/年。每个PI的代金券数量受到限制。通过其程序实现的行政核心 协调员将负责实施和管理该计划。计划指南和 申请说明将张贴在Cobre网站上，申请将提交给该计划 协调员使用基于网络的表格。申请将每年征集四次，并将在 我们的网站以及当地和地区通过全州网络发送的电子邮件。申请将由以下机构审查 内部咨询委员会。标准将包括，1)科学价值，2)与科学主题的一致性 我们的中心，以及3)从预期数据中获得的感知收益(例如，手稿、赠款)。

The proposed P30 Phase III Pilot Project Program will primarily act as a mechanism to fund pilot studies that allow junior and senior investigators to generate preliminary data for submission of grant applications using the unique technologies available in the cores. Through this program we expect to incentivize use of our core technologies enabling all investigators but particularly past and present COBRE target faculty to gather preliminary data to test and develop new hypotheses. As a result, we expect to greatly increase the competitiveness of grant applications that when funded may also require future use of core resources. Since the projects will vary widely in scope and needs, we have decided to create three different routes to fund pilot applications. SC BioCRAFT TIGER CUB grant (up to $10K): These grants will be used to obtain data critical to submission of a larger (R-type) grant. Investigators who have already submitted a grant application to external agencies and are looking to revise their application with new data will be given priority for such an award. SC BioCRAFT TIGER grant ($10k-50K): These grants will be reserved for High Risk- High Reward type applications that propose groundbreaking research in the area of regenerative medicine. These can be single PI or multiple PI proposals. SC BioCRAFT TIGER STREAK grant: ($50k-75K). The purpose of the TIGER STREAK grants program is to provide financial support for the establishment or expansion of multidisciplinary collaborations, which will lead to the development of more competitive, center-type proposals and significant collaborative proposals. Total money available for pilot projects will be $200K/year. Vouchers are to be used to cover the costs of services available through the cores. The annual budget for the voucher program will be $40K /yr. with limitations to the number of vouchers per PI. The Administrative Core through its Program Coordinator will have responsibility for implementing and managing this program. Program guidelines and application instructions will be posted on the COBRE website and applications will be submitted to the Program Coordinator using web-based forms. Applications will be solicited four times annually and will be advertised on our website as well as locally and regionally by emails via statewide networks. Applications will be reviewed by the Internal Advisory Committee. Criteria will include, 1) scientific merit, 2) alignment to the scientific themes of our center, and 3) the perceived benefit (e.g. manuscripts, grants) to be derived from the expected data.