UTMB OAIC Pilot/Exploratory Studies Core (PESC)

UTMB OAIC 试点/探索性研究核心 (PESC)

• 批准号: 10670178
• 负责人: Douglas Paddon-Jones
• 金额: $ 19.95万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10670178
• 关键词: Abbreviations; Address; Aging; American; Applications Grants; Area; Biology; Biometry; Capsicum; Clinical Research; Clinical and Translational Science Awards; Collaborations; Data Management Resources; Development; Discipline; Effectiveness; Elderly; Enrollment; Ensure; Extramural Activities; Funding; Goals; Grant; Hispanic; Hospitalization; Individual; Institution; Institutional Review Boards; Interdisciplinary Study; Intervention; Leadership; Long-Term Care for Elderly; Medical; Mentors; Metabolism; Minority; Mission; Modeling; Monitor; Pathway interactions; Patients; Physical Function; Physical activity; Pilot Projects; Population; Productivity; Recovery; Recovery of Function; Reporting; Research; Research Personnel; Resources; Safety; Stream; Texas; Training; Translating; Translational Research; United States National Aeronautics and Space Administration; Universities; Woman; Women' s Health; acute care; education research; forest; human subject protection; improved; innovation; interest; loss of function; multi-site trial; multidisciplinary; nervous system disorder; nutrition; programs; scale up; success; translational pipeline

PROJECT SUMMARY/ABSTRACT (PESC) The UTMB Pilot/Exploratory Studies Core (PESC) drives the innovation of the UTMB OAIC by supporting the development and maturation of new research programs relevant to our core mission of understanding and improving physical function and independence in older adults. The PESC prioritizes support of early stage investigators, while seeking to build and extend collaborations by attracting established investigators from other disciplines. Over the previous cycles we have supported a high proportion of early stage (71%), women (37%) and minority (34%) investigators. 72% of the pilot studies completed during the past two cycles have led to extramural funding. The PESC funds pilot projects, and small exploratory projects that align with our broader OAIC theme: “Translate Pathways of Function Loss and Gain into Interventions to Optimize Functional Recovery in Diverse Geriatric Populations”. By leveraging institutional resources and OAIC-network collaborations we seek to accomplish the following specific aims: 1. Stimulate new research foci relevant to the OAIC theme. 2. Oversee and monitor the funded projects. 3. Support the development of new research programs. We will accomplish our aims by soliciting, reviewing and selecting meritorious pilot proposals relevant to the OAIC theme; identifying opportunities for collaboration and co-sponsorship of our studies; providing early mentoring support and access to resources from other OAIC cores and institutional facilities; monitoring progress of the funded studies; ensuring regulatory compliance, safety and protection of human subjects; tracking success and productivity of the funded projects; and providing individual mentoring and resources to transition completed PESC studies into competitive, external grant applications. In the next cycle we will expand our breadth by developing new multicenter collaborations with other NIA centers (RCMAR) and other OAICs (Wake Forest), with an emphasis on scaling up trials in hospitalized geriatric patients, neurologic diseases and Hispanic Aging.

项目摘要/摘要（PESC） UTMB飞行员/探索性研究核心（PESC）通过支持驱动UTMB OAIC的创新 与我们理解的核心使命相关的新研究计划的发展和成熟 并改善老年人的身体机能和独立性。 PESC优先考虑早期的支持 舞台调查人员在寻求通过吸引既定调查人员来建立和扩展合作的同时 来自其他学科。在以前的周期中，我们支持了早期的高比例（71％）， 妇女（37％）和少数民族（34％）调查员。在过去的两个中，有72％的试点研究完成 周期导致了卫生资金。 PESC资助了试点项目，以及与我们更广泛的OAIC主题保持一致的小型探索性项目： “将功能损失和增益的途径转化为干预措施，以优化功能恢复 各种老年人群”。通过利用机构资源和OAIC网络合作我们 寻求实现以下特定目标： 1。刺激与OAIC主题相关的新研究重点。 2。监督和监视资助的项目。 3。支持开发新研究计划。 我们将通过征求，审查和选择与该提案相关的有功飞行员提案来实现我们的目标 OAIC主题；确定合作和共同赞助我们的研究的机会；尽早提供 心理支持和从其他OAIC核心和机构设施获得资源；监视 资助研究的进展；确保对人类受试者的规定合规性，安全性和保护； 跟踪资助项目的成功和生产力；并提供个人的心理和资源 过渡完成了PESC研究，以涉及竞争性的外部赠款应用程序。 在下一个周期中，我们将通过与其他NIA开发新的多中心合作来扩大广度 中心（RCMAR）和其他OAICS（Wake Forest），重点是扩大住院试验 老年患者，神经系统疾病和西班牙裔衰老。