Technology to Empower Changes in Health (TECH) Network Participant Technologies Center

技术赋能健康变革 (TECH) 网络参与者技术中心

• 批准号: 10684957
• 负责人: Eric Jeffrey Topol
• 金额: $ 1560.18万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-06 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10684957
• 关键词: Accelerometer; Address; Age; American; Android; Apple; Back; Blue Cross; Blue Shield; Cellular Phone; Climacteric; Communication; Computer software; Consent; Data; Data Analyses; Data Collection; Development; Devices; Ecosystem; Enrollment; Ensure; Foundations; Future; Goals; Growth; Health; Infrastructure; Institutes; International; Internet; Knowledge; Language; Lead; Life; Longitudinal cohort; Maintenance; Medical; Methods; PMI cohort; Participant; Patients; Persons; Population Heterogeneity; Privacy; Provider; Research; Research Personnel; Resources; Safety; Secure; Security; Stream; System; Technology; Telephone; Testing; Time; Translational Research; Vendor; Vision; Work; data acquisition; data communication; data management; design; digital; empowered; experience; flexibility; health care delivery; improved; innovation; lens; mHealth; member; microphone; mobile application; patient engagement; peer; programs; sensor; support network; usability; web services; wireless

Abstract/Project Summary Remarkable advancements in our nation's digital infrastructure combined with explosive growth in pervasive wireless connectivity have created the unprecedented potential to improve both our health and the delivery of healthcare. Beyond their universal availability, smartphones and the mobile networks that support them offer an unparalleled platform for health-related data acquisition and communications. The visionary Precision Medicine Initiative Cohort Program (PMI-CP) is possible, in large part, due to the availability of this digital infrastructure. However, to convert the enormous pool of mostly disjointed information available through a million-person longitudinal cohort into meaningful, life-changing medical knowledge requires development of an innovative, member-centric, engaging, and secure digital network that is state-of-art today, and by design, sustainably so over ensuing years and decades. In order to assure that the PMI-CP achieves its goal to transform the existing culture of medical practice and research by empowering patients, researchers and providers to work together as peers requires the collaborative support of many people with diverse expertise but a singular focus on participant-centeredness. The Participant Technologies Center (PTC) is a critical component to making that happen, and to ensure that we are able to successfully meet the needs of the PMI Steering Committee, and most importantly, the PMI participants, we have formed a network or world-class partners that together have the resources, experience and capabilities necessary to expertly address the known and not-yet known challenges of an endeavor as transformational and far-sighted as the PMI-CP. The Technology to Empower Change in Health (TECH) network is led by Scripps Translational Science Institute and Sage Bionetworks, and includes PatientsLikeMe, Qualcomm, Walgreens, Verizon, Lockheed-Martin, and the Blue Cross Blue Shield Association, bringing together unprecedented experience and knowledge around participant engagement, digital security and personal technologies. Although the PTC is designed to optimize the utilization of technologies in the PMI-CP, our unwavering focus will be on the PMI participant and how to maximize the benefit of participation for them personally. We will accomplish this by laying a foundation built upon personalized engagement strategies, an resolute commitment to security and privacy, and assuring the availability of the state-of-the-art technology needed to meet all current and future data and information sharing needs. .

抽象/项目总结

项目成果

Polygenic risk alters the penetrance of monogenic kidney disease.

• DOI: 10.1038/s41467-023-43878-9
• 发表时间: 2023-12-14
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Khan, Atlas;Shang, Ning;Nestor, Jordan G.;Weng, Chunhua;Hripcsak, George;Harris, Peter C.;Gharavi, Ali G.;Kiryluk, Krzysztof
• 通讯作者: Kiryluk, Krzysztof

Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension.

• DOI: 10.1038/s41467-021-27751-1
• 发表时间: 2022-01-10
• 期刊: Nature communications
• 影响因子: 16.6
• 作者: Wu P;Feng Q;Kerchberger VE;Nelson SD;Chen Q;Li B;Edwards TL;Cox NJ;Phillips EJ;Stein CM;Roden DM;Denny JC;Wei WQ
• 通讯作者: Wei WQ

Racial Disparities in Barriers to Care for Patients With Diabetic Retinopathy in a Nationwide Cohort.

• DOI: 10.1167/tvst.12.3.14
• 发表时间: 2023-03-01
• 期刊: TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
• 影响因子: 3
• 作者: Huang, Bonnie B.;Saseendrakumar, Bharanidharan Radha;Delavar, Arash;Baxter, Sally L.
• 通讯作者: Baxter, Sally L.

Implementing a universal informed consent process for the All of Us Research Program.

为“我们所有人研究计划”实施普遍知情同意流程。

• 发表时间: 2019
• 期刊: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
• 作者: Doerr,Megan;Grayson,Shira;Moore,Sarah;Suver,Christine;Wilbanks,John;Wagner,Jennifer
• 通讯作者: Wagner,Jennifer

Evaluation of Depression and Anxiety in a Diverse Population With Thyroid Eye Disease Using the Nationwide NIH All of Us Database.

使用全国 NIH 所有人数据库对不同甲状腺眼病人群的抑郁和焦虑进行评估。

• DOI: 10.1097/iop.0000000000002318
• 发表时间: 2023
• 期刊: Ophthalmic plastic and reconstructive surgery
• 影响因子: 2
• 作者: Lee,TonyaC;Radha-Saseendrakumar,Bharanidharan;Delavar,Arash;Ye,GordonY;Ting,MichelleA;Topilow,NicoleJ;Bass,Jeremy;Korn,BobbyS;Kikkawa,DonO;Baxter,SallyL;Liu,CatherineY
• 通讯作者: Liu,CatherineY