Scripps Translational Science Institute

斯克里普斯转化科学研究所（STSI）是斯克里普斯中心的中心，成立于2007年，致力于 加速个体化医学，改善医学研究和临床护理，培养未来的领导者， 生物医学劳动力。Scripps中心包括Scripps研究所（TSRI）和Scripps Health（SH）， 其主要组成部分，以及圣地亚哥超级计算机中心的生物信息学计划，沿着。新 CTSA周期，我们的合作伙伴已经扩大到现在包括加州医学研究所（Calibr），最近 建立了斯克里普斯研究所和拉迪儿童基因组医学研究所（RCIGM）。这两个新 合作伙伴将显著增加我们在药物再利用/发现方面的努力，并在整个生命周期内为儿科患者提供更多的药物。 人口数字医学一直是STSI的核心优势之一，其创新可以从端到端地支持临床试验。 结束（注册到传播）。我们对人类基因组学的关注对于在中心建设基础设施至关重要， 支持整个圣地亚哥地区的许多研究，包括健康老龄化（Wellderly），未知疾病， 通过测序进行分子解剖和快速病原体检测。我们得到了CTSA试验的支持 创新网络（TIN）为其中2个项目。最近STSI支持的项目融合了基因组学和 用于移动的应用程序开发和临床试验的数字医学。对STSI进步的重要肯定， 2016年，NIH将其选为精准医学倡议的参与者中心 (PMI)我们都是一个队列。 斯克里普斯中心的许多其他方面正在经历显着的增长。我们的生命科学行业合作伙伴， 作为STSI的一项重要战略，在过去的CTSA周期中，已经扩大了20多项新的合作。几 这些都导致了独家大数据分析计划，累计，与沃尔格林，Withings和Fitbit，涉及数十个 使用移动终端传感器的数百万人。斯克里普斯中心的社区参与研究 在我们与San Francisco代表性不足的少数民族合作的记录基础上， 迭戈县和数字医学技术的专业知识。我们的中心间合作和积极参与 CTSA联盟显著增加，我们的教育和培训举措也是如此。我们开发了新 进一步加强劳动力多样性和创业培训的举措。这些努力最近得到了以下方面的补充： 斯克里普斯研究生物科学学院将开始招收本科生攻读学士学位 年

The Scripps Translational Science Institute (STSI) is the center of the Scripps Hub, formed in 2007, dedicated to accelerating individualized medicine, improving medical research and clinical care, and training the future leaders of the biomedical workforce. The Scripps hub has included The Scripps Research Institute (TSRI) and Scripps Health (SH) as its principal components, along with the San Diego Supercomputer Center for its bioinformatic initiatives. In the new CTSA cycle, our partners have expanded to now include the California Institute for Medical Research (Calibr), recently made a Scripps Research Institute, and the Rady Children's Institute of Genomic Medicine (RCIGM). These 2 new partners will markedly increase our efforts for drug repurposing/ discovery and across the lifespan to the pediatric population. Digital medicine has been one of STSI's core strengths, with innovations to digitize clinical trials from end-to- end (enrollment to dissemination). Our focus on human genomics has been critical to building infrastructure at the hub, supporting many studies throughout the San Diego region including healthy aging (Wellderly), unknown diseases, molecular autopsy and rapid pathogen detection through sequencing. We received support from the CTSA Trial Innovation Network (TIN) for 2 of these projects. Recent STSI-supported projects feature a fusion of both genomics and digital medicine for mobile app development and clinical trials. An important affirmation of STSI's progress and contributions was its selection in 2016 by the NIH to be The Participant Center for the Precision Medicine Initiative (PMI) All of Us cohort. Many other aspects of the Scripps hub are undergoing remarkable growth. Our life science industry partners, which has been an essential STSI strategy, has expanded with more than 20 new collaborations over the past CTSA cycle. A few of these have led to exclusive big data analytic programs, cumulatively, with Walgreens, Withings, and Fitbit, involving tens of millions of individuals using mobile device sensors. Community engagement research at the Scripps hub has blossomed with 3 new RO1 grants that build on our track record of working with underrepresented minorities in San Diego County and expertise in digital medicine technology. Our inter-hub collaborations and active participation in the CTSA Consortium have markedly increased, as have our educational and training initiatives. We have developed new initiatives to further enhance workforce diversity and entrepreneurial training. These efforts are newly complemented by the Scripps Research Biosciences College that will begin enrolling undergraduate students for a baccalaureate degree next year.