Leadership & Administration Core

科罗拉多州性别差异和妇女健康卓越研究专业中心

The Colorado Specialized Center of Research Excellence (SCORE) on Sex Differences and Women’s Health is focused on Bioenergetic and Cardiometabolic Consequences of the Loss of Gonadal Function. The overarching scientific goal of the SCORE is to address gaps in knowledge of the impact of gonadal aging on the regulation of energy homeostasis and metabolism by conducting mechanistically driven research across the basic-to-clinical translational spectrum. The Colorado SCORE is focused on the increased propensity for abdominal fat accumulation and the associated cardiometabolic dysfunction that are consequent to the loss of ovarian function. The overarching educational goal is to engage new investigators in research aligned with the focus of the SCORE through mentoring and training activities to enhance career development. The Leadership Administrative Core (LAC) provides infrastructural support that ensures the scientific and educational goals can be achieved. Major LAC objectives: 1) provide scientific leadership for a translational and transdisciplinary research program focused on the consequences of the loss of gonadal function that increase risk for age-related diseases; 2) evaluate the progress and productivity of the SCORE Research Projects and, if necessary, make decisions about the reallocation of resources; 3) foster collaboration among the SCORE Research Projects, Pilot Projects, SCORE Scholars, faculty, and staff, 4) promote the generation of new translational research opportunities related to the focus of the SCORE through the Career Enhancement Core (CEC) awards and through collaborations with other SCOREs; 5) integrate activities of the SCORE with closely aligned Centers and Programs at the University of Colorado Anschutz Medical Campus (CU-AMC), including the Multidisciplinary Center on Aging (MCoA), Ludeman Family Center for Women’s Health Research (CWHR), Colorado Clinical and Translational Sciences Institute (CCTSI), Nutrition Obesity Research Center (NORC), and multiple institutional training grants; 6) provide statistical, data management, and evaluation support for the SCORE Research Projects and Pilot Projects; and 7) provide administrative support for financial oversight, regulatory oversight, and scheduling and general management of all SCORE activities. To carry out these objectives effectively, the LAC will include a Director, Associate Director, 8- member Executive Committee, 3-member Internal Advisory Board (IAB), 3-member External Advisory Board (EAB), and LAC support staff. The SCORE investigators and advisors have complementary strengths that elevate the impact of the SCORE both locally and nationally. They are renowned scientists with experience in interdisciplinary and translational research aligned with the focus of the SCORE, and they hold leadership positions on strategically important committees, boards, centers, and training grants that enable them to catalyze SCORE collaborations. The Colorado SCORE team is exceptionally well-positioned to advance research on sex differences that impact women’s health.