Administrative Core

行政核心

• 批准号: 7617317
• 负责人: RUTH Hogue ANGELETTI
• 金额: $ 6.53万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2011-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7617317
• 关键词: AIDS/HIV problem; Administrative Personnel; Advisory Committees; Animal Model; Bioinformatics; Biological Markers; Buprenorphine; Cell Culture Techniques; Development; Disease; Drug Addiction; Drug abuse; Ensure; Equipment; Fostering; Grant; HIV; HIV Infections; Hand; Human; Laboratories; Maintenance; Management Information Systems; Mission; Neurocognitive; Participant; Preparation; Problem Solving; Progress Reports; Proteomics; Publications; Reagent; Research; Schedule; Site; Visit; Work; data integration; meetings; member; symposium; web site

The mission of the Einstein HAND Proteomics Research Center is to evaluate the interactions of drug addiction and its treatment on the development and progression of HIV associated neurocognitive disorders (HAND). The central research themes of the pilot Einstein HAND Proteomics Research Center (EHPRC) will focus on investigating the mechanism by which HIV infection causes HAND, identifying biomarkers for the onset and course of HAND and the potential additive impact of buprenorphine treatment on the development and progression of HAND by utilizing proteomic approaches in humans, animal models and cell culture. The EHPRC will provide the proteomics, bioinformatics, data integration, and statistical support for three synergistic projects. Scientific interactions and project integration will be fostered by a laboratory information management system (LIMS), an EHPRC web site, weekly lab meetings of EHPRC members, and annual presentations at meetings with internal and external advisory committees.

爱因斯坦HAND蛋白质组学研究中心的任务是评估