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Mass Spectrometer System

Mass Spectrometer System
质谱仪系统
批准号：
6733184
负责人：
RUTH Hogue ANGELETTI
金额：
$37.87万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
项目状态：
已结题
起止时间：
2004-04-01 至 2005-03-31
来源：
https://reporter.nih.gov/project-details/6733184
关键词：
biomedical equipment purchasehigh performance liquid chromatographymass spectrometryproteomics

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英文摘要
DESCRIPTION (provided by applicant): Funds are requested for a mass spectrometer system, composed of a ThermoFinnigan LCQ Deca XP Plus ultra sensitive MS n ion trap mass spectrometer and atmospheric pressure MALDI ion source, with a nanoliter flow HPLC capable of two-dimensional chromatography. This instrument system provides high sensitivity and mass accuracy with tandem mass spectrometry capabilities. It is ideally suited for proteomics applications, characterization of macromolecular assembles, and identification of patterns of biomarkers and potential therapeutics in technology transfer applications. Thirteen groups of investigators participate in this proposal, which includes projects in understanding the mechanisms of obesity, meiosis, signal transduction, HIV/AIDS, infectious diseases and cancer. The instruments will be operated and supervised by experienced mass spectrometrists and protein chemists within an existing shared protein core facility with a record of productivity and collaborative interactions.
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