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Meta-Analysis of Interventions to Increase Exercise/Physical Acivity

增加运动/身体活动干预措施的荟萃分析

基本信息

批准号：
7559547
负责人：
Vicki S Conn
金额：
$ 40.4万
依托单位：
UNIVERSITY OF MISSOURI-COLUMBIA
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-04-01 至 2011-01-31
项目状态：
已结题

项目摘要

Adequate physical activity can prevent or delay many chronic illnesses and enhance the quality of life. Despite these well-documented benefits, people adopt and maintain exercise at alarmingly low rates, and far too many people are entirely sedentary. This is due in part to our limited understanding of which interventions work to increase activity. Although many primary studies have tested interventions designed to increase activity, their findings remain unsynthesized, a condition that seriously impedes progress in both research and practice. The purpose of this project is to integrate scientific knowledge about interventions to increase physical activity in healthy people. The project addresses these specific aims: ¿ Determine the strength of the research base about interventions to increase physical activity. ¿ Specify the effect of interventions on physical activity and exercise behavior. ¿ Distinguish factors that moderate the effect of interventions to increase exercise and physical activity. Our research team has used the proposed methods in a published synthesis focused on aging subjects and in an in-progress NIH-funded meta-analysis of exercise interventions among chronically ill adults. An extremely extensive and rigorous literature search will avoid the bias caused by typical limited searches. Strategies include computerized searches, ancestry searches, registry and database searches, hand searches of selected journals, reviews of graduate projects, examination of conference/association abstracts, and contacts with senior authors on retrieved studies and principal investigators of NIH-funded studies. Independent data extractors will reliably code intervention, methodological and participant attributes that address the research aims. Analysis plans include: cf-index to standardize the magnitude of effect, both unweighted and sample size weighted calculations, analyses under both fixed and random effects models, potential control for methodological moderators in subsequent analysis, and homogeneity analysis (Qt, Qw) to detect intervention component effects. For example, the moderator analysis will reveal intervention characteristics (e.g. self-monitoring) are associated with larger increases in physical activity. Minority and gender differences in intervention effectiveness will be examined as well. Findings will improve public health by synthesizing diverse results so that interventions can be designed for effective programs that help people increase their physical activity to meet public health goals. The compelling importance and broad scope of this work make funding necessary to achieve these important aims.

充足的体力活动可以预防或延缓许多慢性病，提高生活质量。尽管有这些有据可查的好处，但人们采用并保持锻炼的比率低得惊人，而且远远太多的人完全久坐不动。这在一定程度上是由于我们对干预措施的作用是增加活动。尽管许多初步研究已经测试了旨在增加活动，但他们的发现仍然没有综合，这一状况严重阻碍了这两个领域的进展研究和实践。该项目的目的是将有关干预措施的科学知识整合到增加健康人的体力活动。该项目涉及以下具体目标：确定关于增加体力活动的干预措施的研究基础的强度。？具体说明干预措施对身体活动和锻炼行为的影响。区分影响增加锻炼和体力活动的干预措施效果的因素。我们的研究团队将建议的方法用于发表的一项专注于衰老主题的综述中，并在一项由美国国立卫生研究院资助的对患有慢性病的成年人进行的运动干预的荟萃分析中。一个极其广泛和严谨的文献搜索将避免典型的有限搜索造成的偏见。战略包括计算机化搜索、血统搜索、登记册和数据库搜索、手工搜索。搜索选定的期刊，审查研究生项目，审查会议/协会摘要，以及与NIH资助的检索研究的资深作者和主要研究人员的联系学习。独立的数据提取人员将可靠地对干预、方法和参与者属性进行编码这解决了研究的目标。分析计划包括：对CF指数进行标准化影响的大小，既有未加权和样本量加权计算，固定和随机效应模型下的分析，在后续分析和同质性分析(Qt，QW)中对方法主持人的潜在控制检测干预组件效果。例如，主持人分析将显示干预特征(如自我监控)与较大的体力活动增加有关。少数族裔和此外，还将考察干预效果的性别差异。研究结果将改善公众健康通过综合不同的结果，以便为帮助人们的有效计划设计干预措施增加他们的体力活动，以达到公共卫生目标。令人信服的重要性和广泛的范围这项工作为实现这些重要目标提供了必要的资金。