MI Center for Contextual Factors in Alzheimer's Disease (MCCFAD) Yrs 6-10

摘要：总体 密歇根阿尔茨海默病背景因素中心（MCCFAD）旨在促进和 加强阿尔茨海默病和相关痴呆症（ADRD）的创新研究， 长期目标：1）推进ADRD相关的社会和行为科学研究， 服务不足和代表性不足的社区，同时; 2）多样化的研究队伍 致力于健康老龄化。该中心建立在一个长期的承诺，以促进多样性，公平， 包容和获取（DEIA），以及ADRD的现有基础设施和研究优势， 密歇根大学（UM）的老龄化研究。该中心的重点是ADRD是 经验丰富。关于ADRD背景的知识相当有限，但已被证明是至关重要的， 阐明造成健康差距的社会文化、经济和行为因素及其后果 一般来说，ADRD差异具体。MCCFAD强调ADRD研究在三个优先领域： 流行病学，卫生经济学和文化敏感的护理。这三个领域的基本原理直接 与继续缺乏对《公约》所固有的背景复杂性的全面了解有关， ADRD差异，需要加强解决大脑问题的专业研究队伍的多样性 老年人的认知健康，以及人口和多元文化的动态变化， 美国人口组成。MCCFAD促进研究人员的多样化，致力于 通过与R1的联系，与其他NIA赞助的中心和项目合作，实现健康老龄化， R2和密歇根州的博士/专业大学，并通过管理包容性和无障碍 为不同的学者提供教育计划。该中心的四个核心是：领导和行政（LAC）， 研究和教育（REC），分析（AnC）和社区联络和招聘（CLRC）。具体 目的是：（1）推进ADRD相关的流行病学、卫生经济学和 （2）从试点研究者中招募并指导15名AD-RCMAR科学家（RS） 通过专业出版物和独立的研究申请和资助阶段;（3）与 中东北非（MENA）和拉丁美洲社区，以扩大内部和内部的理解， 影响参与ADRD研究的文化因素。该中心从开创性的利润， 他们的经验丰富的导师和专家的广泛网络的成功工作。这些资源，沿着 计划的结构和活动将确保MCCFAD将继续在以下方面产生重大影响： 使致力于健康老龄化的研究人员多样化，同时加强研究，以更好地了解 AD和各种背景下的痴呆症相关形式。

ABSTRACT: OVERALL The Michigan Center for Contextual Factors in Alzheimer’s Disease (MCCFAD) aims to foster and enhance innovative research in Alzheimer’s disease and related dementias (ADRD) with the long term goals to 1) advance ADRD-relevant social and behavioral science research in underserved and underrepresented communities while; 2) diversifying the research workforce dedicated to healthy aging. This Center builds on a longstanding commitment to advance Diversity, Equity, Inclusion and Access (DEIA), as well as deep existing infrastructure and research strengths in ADRD and aging research at the University of Michigan (UM). The Center focuses on the contexts in which ADRD is experienced. Knowledge concerning the contexts of ADRD is quite limited but has been shown to be critical for elucidating sociocultural, economic and behavioral contributors to and consequences of health disparities generally and ADRD disparities specifically. The MCCFAD emphasizes ADRD research in three priority areas: epidemiology, health economics, and culturally sensitive care. The rationale for these three areas is directly related to the continued lack of a comprehensive understanding of the contextual complexities inherent in ADRD disparities, the need to enhance diversity in the professional research workforce addressing the brain and cognitive health of older adults, as well as dynamic changes in the demographic and multi-cultural composition of the U.S. population. The MCCFAD promotes diversifying the research workforce dedicated to healthy aging through collaborations with other NIA-sponsored Centers and programs via connections with R1, R2 and doctoral/professional universities in Michigan, and by administering inclusive and accessible educational programs for diverse scholars. The Center’s four Cores are: Leadership and Administrative (LAC), Research and Education (REC), Analytic (AnC), and Community Liaison and Recruitment (CLRC). Specific aims are to: (1) Advance ADRD-relevant disparities research in epidemiology, health economics, and culturally-sensitive care; (2) Recruit and mentor 15 AD-RCMAR Scientists (RS) from the pilot-study investigator stage through professional publications and independent research applications and funding; (3) Connect with Middle Eastern North African (MENA) and Latino communities to broaden understanding of intra- and inter- cultural factors affecting participation in ADRD research. The Center profits from the groundbreaking, successful work of their extensive network of experienced mentors and experts. These resources, along with planned structure and activities will ensure that the MCCFAD will continue to have a significant impact in diversifying the research workforce dedicated to healthy aging while enhancing research to better understand AD and related forms of dementia across various contexts.