MI Center for Contextual Factors in Alzheimer's Disease (MCCFAD) Yrs 6-10

摘要：总体 密歇根阿尔茨海默病背景因素中心(MCCFAD)旨在促进和 加强阿尔茨海默病和相关痴呆症(ADRD)的创新研究 长期目标：1)推进与ADRD相关的社会和行为科学研究 服务不足和代表性不足的社区；2)使研究人员多样化 致力于健康衰老。该中心建立在促进多样性、公平、 包容性和可获取性(DeIA)，以及ADRD和 密歇根大学(UM)的老龄化研究。该中心重点关注ADRD所处的环境 经验丰富。关于ADRD背景的知识相当有限，但已被证明对 阐明造成健康差距的社会文化、经济和行为因素及其后果 总体而言，尤其是ADRD的差距。MCCFAD强调在三个优先领域开展ADRD研究： 流行病学、卫生经济学和文化敏感护理。这三个领域的基本原理是直接的 与继续缺乏对以下方面固有的背景复杂性的全面了解有关 ADRD差异，需要加强解决大脑问题的专业研究人员的多样性 和老年人的认知健康，以及人口和多元文化的动态变化 美国人口的构成。MCCFAD促进致力于以下方面的研究队伍的多样化 通过与NIA赞助的其他中心和计划的合作，通过与R1的联系实现健康老龄化， R2和密歇根的博士/专业大学，并通过管理包容性和可访问性 针对不同学者的教育项目。该中心的四个核心是：领导和行政(LAC)， 研究和教育(REC)、分析(ANC)和社区联络和招募(CLRC)。特定的 目标是：(1)推进流行病学、卫生经济学和 对文化敏感的护理；(2)从先导研究调查员中招聘和指导15名AD-RCMAR科学家(RS) 通过专业出版物和独立研究申请和资金的阶段；(3)连接 中东北非(MENA)和拉丁裔社区，以扩大对 影响参与ADRD研究的文化因素。中心从开创性工作中获利， 成功的工作得益于他们由经验丰富的导师和专家组成的广泛网络。这些资源，以及 计划的结构和活动将确保MCCFAD将在#年继续产生重大影响 使致力于健康老龄化的研究队伍多样化，同时加强研究以更好地了解 各种情况下的AD和相关形式的痴呆症。

ABSTRACT: OVERALL The Michigan Center for Contextual Factors in Alzheimer’s Disease (MCCFAD) aims to foster and enhance innovative research in Alzheimer’s disease and related dementias (ADRD) with the long term goals to 1) advance ADRD-relevant social and behavioral science research in underserved and underrepresented communities while; 2) diversifying the research workforce dedicated to healthy aging. This Center builds on a longstanding commitment to advance Diversity, Equity, Inclusion and Access (DEIA), as well as deep existing infrastructure and research strengths in ADRD and aging research at the University of Michigan (UM). The Center focuses on the contexts in which ADRD is experienced. Knowledge concerning the contexts of ADRD is quite limited but has been shown to be critical for elucidating sociocultural, economic and behavioral contributors to and consequences of health disparities generally and ADRD disparities specifically. The MCCFAD emphasizes ADRD research in three priority areas: epidemiology, health economics, and culturally sensitive care. The rationale for these three areas is directly related to the continued lack of a comprehensive understanding of the contextual complexities inherent in ADRD disparities, the need to enhance diversity in the professional research workforce addressing the brain and cognitive health of older adults, as well as dynamic changes in the demographic and multi-cultural composition of the U.S. population. The MCCFAD promotes diversifying the research workforce dedicated to healthy aging through collaborations with other NIA-sponsored Centers and programs via connections with R1, R2 and doctoral/professional universities in Michigan, and by administering inclusive and accessible educational programs for diverse scholars. The Center’s four Cores are: Leadership and Administrative (LAC), Research and Education (REC), Analytic (AnC), and Community Liaison and Recruitment (CLRC). Specific aims are to: (1) Advance ADRD-relevant disparities research in epidemiology, health economics, and culturally-sensitive care; (2) Recruit and mentor 15 AD-RCMAR Scientists (RS) from the pilot-study investigator stage through professional publications and independent research applications and funding; (3) Connect with Middle Eastern North African (MENA) and Latino communities to broaden understanding of intra- and inter- cultural factors affecting participation in ADRD research. The Center profits from the groundbreaking, successful work of their extensive network of experienced mentors and experts. These resources, along with planned structure and activities will ensure that the MCCFAD will continue to have a significant impact in diversifying the research workforce dedicated to healthy aging while enhancing research to better understand AD and related forms of dementia across various contexts.