Vision Research Training Program

描述(由申请人提供)：我们斯坦福大学眼科和视力与预防失明中心正在向国家眼科研究所申请T32培训补助金，以资助旨在整合基础视力研究和临床眼科培训的博士后项目。我们的目标包括：1)密集的临床眼科接触，特别是针对非临床训练有素的研究人员，以促进未来基础视力研究在床上的应用；2)促进医学博士和医学博士实习生从临床过渡到临床 3)在分子、细胞、突触和系统水平的视觉研究方面对来自不同背景的基础和临床研究人员进行教育和培训，为他们在临床和基础科室的学术生涯做好准备。在你们的帮助下，我们计划每年培养4名医学博士、博士或医学博士研究生。基础视力研究和眼科学(眼科学302a)的强化课程、斯坦福视力与失明预防中心每周的多学科讲座和研讨会，以及其他视力课程和流行病学和统计学方面的培训，都将是根据每个学员的背景和研究兴趣量身定做的教育计划，以及每年展示他们的工作、授课、撰写拨款申请和参加科学会议的机会。每位学员将被分配一名基础科学和一名临床导师，他们是从斯坦福大学视力研究人员中挑选出来的，他们总共拥有国家眼科研究所的16项R01资助，并发表了100多篇同行评议文章 最近两年的出版物。这些导师帮助每位学员发表基础和临床论文，作为严格的科学和临床研究的范例，并帮助制定全面的计划，将眼睛和视觉回路的发育模式、突触可塑性和视觉通路的处理、视觉对象识别和阅读、视觉-运动整合等基础领域的知识与详细了解低视力和失明常见原因的诊断和治疗以及用于解决这些问题的工具相结合。一个外部咨询委员会对该方案的运作提供独立的观点。 与公共健康相关：由于我们的项目旨在为每位学员提供对视力研究及其应用程序的全面了解，以防止视力丧失，我们的学员准备为解决失明和低视力的不同原因做出重大研究贡献，仅考虑到主要的成人视力障碍，失明和低视力影响全球1.6亿人，每年给美国造成354亿美元的经济负担。

DESCRIPTION (provided by applicant): We at the Stanford Department of Ophthalmology and Center for Vision and Prevention of Blindness are applying for a T32 Training Grant from the National Eye Institute to fund a the post-doctoral program designed to Integrate basic vision research and clinical ophthalmologic training. Our goals include: 1) intensive clinical ophthalmologic exposure, especially targeting non-clinically trained investigators, to facilitate future bench-to-bedside applications of basic vision research; 2) facilitation of the transition of M.D. and M.D.-Ph.D.-trainees from clinical practice to rigorous vision research and fostering their successful application to the Career development (K) Award, an important funding mechanism for physician-scientists; and 3) the education and training of basic and clinical investigators from diverse backgrounds in molecular, cellular, synaptic, and systems level vision research to prepare them for academic careers in clinical and basic departments. With your help, we plan to train 4 M.D., Ph.D., or M.D.-Ph.D. fellows per year. An intensive course on basic vision research and ophthalmology (Ophthalmology 302A), weekly multi-disciplinary Stanford Center for Vision and Prevention of Blindness lectures and seminars, and other vision courses and training in epidemiology and statistics will be among the educational program tailored to each trainee's background and research interest, along with annual opportunities to present their work, teach, write grant applications, and attend scientific meetings. Each trainee will be assigned a basic science and a clinical mentor, chosen from Stanford vision investigators which collectively hold 16 R0l grants from the National Eye Institute and have published over 100 peer-reviewed publications in the last 2 years. These mentors help each trainee publish basic and clinical papers, serve as examples of rigorous scientific and clinical Investigations, and help develop a well-rounded program to interweave knowledge in basic areas such as developmental patterning of the eye and visual circuitry, synaptic plasticity and processing of the visual pathway, visual object recognition and reading, and visual-motor integration with a detailed understanding of the diagnosis and treatment of common causes of low vision and blindness and tools used to address them. An External Advisory Committee offers independent perspectives on the Program's operation. PUBLIC HEALTH RELEVANCE: Because our program is designed to provide each trainee with a comprehensive understanding of vision research and its applications to prevent vision loss, our trainees are poised to make significant research contributions to tackle the different causes of blindness and low vision, which affects 160 million people worldwide and costs the United States annually 35.4 billion dollars in financial burden when considering just the major adult visual disorders.