Administrative Core

项目总结 新型冠状病毒(新冠肺炎)加剧了全美(美国)和 对美国印第安人/阿拉斯加原住民(AI/AN)人口产生了重大影响。亚利桑那州 拥有世界上第三大 美国人工智能/人工智能人口(超过35万人)，是22个联邦承认的主权土著民族的家园。 与白人相比，亚利桑那州AI/AN的健康风险因素患病率显著高于白人 增加他们对新冠肺炎的易感性。AI/An约占该州人口的4.6%，但 在新冠肺炎上报告的受害者种族和民族死亡人数中，有19%是由这一事件造成的。的长期目标是 这项研究旨在开展社区参与的研究和外联活动，以提高对新冠肺炎的认识和 亚利桑那州人工智能/人工智能社区的教育受到新冠肺炎的不成比例影响，并将减少 错误信息和不信任。这一行政副刊的目标是建立有效的、文化上的 采取适当战略，加强AI/AN社区在预防和治疗COVID方面的参与 19，包括疫苗试验和未来的疫苗接种。这项工作将由社区参与指导 框架，强调科学家和社区成员之间的平等参与 研究的各个阶段。与母公司U54 RCMI集水区的AI/AN社区合作： 西南卫生公平研究合作(SHERC)，我们的目标是：1)评估知晓率， 关于新冠肺炎疫苗试验和接种的知识、经验、关注、态度和需求 亚利桑那州人工智能/人工智能社区的接受情况；2)发展和适应适合文化的教育 旨在提高人们对新冠肺炎疫苗试验的认识，减少错误信息， 并增加医疗信任；3)实施教育会议，评估教育的影响 关于增强意识、信任、自我效能以及参与意愿和意图的材料和战略 在新冠肺炎疫苗试验和未来的疫苗中。迫切需要更好地解决以下问题 在亚利桑那州新冠肺炎大流行的这一关键时刻，AI/AN社区。由此衍生出的知识 这项研究有可能提高人们对新冠肺炎疫苗试验的认识，并加强 试验中的AI/ANS和未来的疫苗接种。SHERC独特的地理和文化背景， 结合这个跨学科调查团队的经验和专业知识，很好地定位了 为成功而提出的研究建议。

PROJECT SUMMARY The novel coronavirus (COVID-19) has exacerbated health disparities throughout the United States (US) and impacted American Indian/Alaska Native (AI/AN) populations in significant ways. Arizona has the third largest population of AI/AN in the US (over 350,000) and is home to 22 federally recognized sovereign Native nations. Compared with Whites, AI/AN in Arizona have a significantly higher prevalence of health risk factors that increase their susceptibility to COVID-19. AI/AN represent approximately 4.6% of the state’s population, yet account for 19% of COVID-19 deaths where race and ethnicity of victims is reported. The long-term goal of this study is to conduct community-engaged research and outreach to increase COVID-19 awareness and education among AI/AN communities in Arizona disproportionately affected by COVID-19 and to reduce misinformation and mistrust. The goal of this Administrative Supplement is to establish effective, culturally appropriate strategies to enhance participation of AI/AN communities in prevention and treatment of COVID- 19, including vaccine trials and future vaccine uptake. This work will be guided by a community engagement framework, which emphasizes equitable participation between scientists and community members in all phases of the research. In partnership with AI/AN communities in the catchment area of the parent U54 RCMI: The Southwest Health Equity Research Collaborative (SHERC), we aim to: 1) Assess awareness, knowledge, experiences, concerns, attitudes, and needs regarding COVID-19 vaccine trials and vaccination uptake among AI/AN communities in Arizona; 2) Develop and adapt culturally-appropriate educational materials and strategies designed to increase awareness of COVID-19 vaccine trials, decrease misinformation, and increase medical trust; and 3) Implement the educational session and evaluate the impact of educational materials and strategies on enhanced awareness, trust, self-efficacy, and willingness and intent to participate in COVID-19 vaccine trials and future vaccines. There is an urgent need to better address the concerns of AI/AN communities at this critical juncture of the COVID-19 pandemic in Arizona. Knowledge derived from this study has the potential to build awareness about COVID-19 vaccine trials and enhance participation among AI/ANs in the trials and future vaccine uptake. The unique geographical and cultural setting of SHERC, combined with the experience and expertise of this interdisciplinary team of investigators, well-positions the proposed study for success.