Training in Malaria Research in Myanmar
缅甸疟疾研究培训
基本信息
- 批准号:10239898
- 负责人:
- 金额:$ 24.84万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-03-15 至 2027-02-28
- 项目状态:未结题
- 来源:
- 关键词:AccountingAchievementAddressAntimalarialsAreaArtemisininsBedsCountryDisciplineDiseaseEducational workshopEffectivenessEnsureEpidemiologyFacultyFloridaGoalsHeterogeneityInsecticide ResistanceInsecticidesKnowledgeMalariaMeasuresMedicineMentorsMonitorMorbidity - disease rateMyanmarNeeds AssessmentPlasmodium falciparumPlasmodium vivaxPostdoctoral FellowPublic HealthResearchResearch PersonnelResidual stateResistanceScientistSoutheastern AsiaTechnical ExpertiseTechnologyTrainingTraining ProgramsUniversitiesbasecareerclinical efficacydesigndoctoral studentinnovationmembermortalitymultidisciplinaryprogramspyrethroidresistance mechanismvectorvector controlvector mosquito
项目摘要
Project Summary
Malaria in the Greater Mekong Subregion (GMS) of Southeast Asia remains an important public health
problem. Motivated by recent achievements in the reduction of malaria-related morbidity and mortality, six
GMS countries have endorsed a regional malaria elimination plan with the ultimate goal to wholly eliminate
malaria by 2030. However, this ambitious plan encounters a battery of challenges that must be addressed
urgently. In the GMS, malaria shows tremendous heterogeneity in disease distribution, with Myanmar
accounting for nearly half of the region confirmed malaria cases. The recent emergence of artemisinin
resistance in Plasmodium falciparum and deteriorating efficacy of the frontline treatment for Plasmodium vivax
are major concerns for malaria elimination. Furthermore, the emergence of insecticide resistance in major
malaria vectors compromises the effectiveness of the core vector control measures such as insecticide-treated
bed nets and indoor residual spraying. Despite the need for strengthened research to address these problems,
there is a critical shortage in a well-trained workforce in malaria research in Myanmar. Therefore, this training
program will address key knowledge gaps in malaria research, focusing on three scientific areas. Specifically,
we aim to understand the changing malaria epidemiology in this region, to closely monitor the clinical efficacies
of antimalarial drugs and elucidate the underlying resistance mechanisms, and to determine the extent,
distribution, and mechanisms of pyrethroid resistance in major malaria vector mosquitoes. Within this training
program, mentors of diverse scientific disciplines from the University of South Florida and University of
Medicine Magway will join forces to offer multidisciplinary training in innovative approaches that address critical
problems in the current malaria elimination campaign in this region. Based on training needs assessment, we
propose to use a double-track training mechanism: 1) long-term training of three junior faculty members, three
postdoctoral fellows and six PhD students, and 2) short-term training of endemic country scientists through
annual short courses and workshops. The overall training paradigm designed in this application will ensure that
all trainees obtain the required set of technical skills and intellectual expertise to conduct independent research
on malaria. In addition, this training program will serve as an important platform for the transfer of enabling
technologies to endemic-area scientists. By advancing the careers of these trainees, this program aims to build
a critical mass of investigators and a necessary intellectual network in Myanmar to focus on malaria research.
项目总结
项目成果
期刊论文数量(0)
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会议论文数量(0)
专利数量(0)
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{{ truncateString('LIWANG CUI', 18)}}的其他基金
Transcriptomes and Proteomes of Plasmodium Vivax
间日疟原虫的转录组和蛋白质组
- 批准号:
9241966 - 财政年份:2016
- 资助金额:
$ 24.84万 - 项目类别:
Puf-Mediated Translation Control in Plasmodium
疟原虫中 Puf 介导的翻译控制
- 批准号:
9109554 - 财政年份:2014
- 资助金额:
$ 24.84万 - 项目类别:
Puf-Mediated Translation Control in Plasmodium
疟原虫中 Puf 介导的翻译控制
- 批准号:
9314354 - 财政年份:2014
- 资助金额:
$ 24.84万 - 项目类别:
Administration of Southeast Asia Malaria Research Center
东南亚疟疾研究中心管理局
- 批准号:
8500153 - 财政年份:2013
- 资助金额:
$ 24.84万 - 项目类别:
Malaria Vector Population Genetic Division and Vector Competence in Hainan Island
海南岛疟疾媒介群体遗传划分及媒介能力
- 批准号:
8210435 - 财政年份:2012
- 资助金额:
$ 24.84万 - 项目类别:
Sex-Specific Gene Expression in Malaria Parasite Plasmodium falciparum
疟疾寄生虫恶性疟原虫的性别特异性基因表达
- 批准号:
8385372 - 财政年份:2012
- 资助金额:
$ 24.84万 - 项目类别:
Sex-Specific Gene Expression in Malaria Parasite Plasmodium falciparum
疟疾寄生虫恶性疟原虫的性别特异性基因表达
- 批准号:
8495258 - 财政年份:2012
- 资助金额:
$ 24.84万 - 项目类别:
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