Training in Malaria Research in Myanmar
缅甸疟疾研究培训
基本信息
- 批准号:10239898
- 负责人:
- 金额:$ 24.84万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-03-15 至 2027-02-28
- 项目状态:未结题
- 来源:
- 关键词:AccountingAchievementAddressAntimalarialsAreaArtemisininsBedsCountryDisciplineDiseaseEducational workshopEffectivenessEnsureEpidemiologyFacultyFloridaGoalsHeterogeneityInsecticide ResistanceInsecticidesKnowledgeMalariaMeasuresMedicineMentorsMonitorMorbidity - disease rateMyanmarNeeds AssessmentPlasmodium falciparumPlasmodium vivaxPostdoctoral FellowPublic HealthResearchResearch PersonnelResidual stateResistanceScientistSoutheastern AsiaTechnical ExpertiseTechnologyTrainingTraining ProgramsUniversitiesbasecareerclinical efficacydesigndoctoral studentinnovationmembermortalitymultidisciplinaryprogramspyrethroidresistance mechanismvectorvector controlvector mosquito
项目摘要
Project Summary
Malaria in the Greater Mekong Subregion (GMS) of Southeast Asia remains an important public health
problem. Motivated by recent achievements in the reduction of malaria-related morbidity and mortality, six
GMS countries have endorsed a regional malaria elimination plan with the ultimate goal to wholly eliminate
malaria by 2030. However, this ambitious plan encounters a battery of challenges that must be addressed
urgently. In the GMS, malaria shows tremendous heterogeneity in disease distribution, with Myanmar
accounting for nearly half of the region confirmed malaria cases. The recent emergence of artemisinin
resistance in Plasmodium falciparum and deteriorating efficacy of the frontline treatment for Plasmodium vivax
are major concerns for malaria elimination. Furthermore, the emergence of insecticide resistance in major
malaria vectors compromises the effectiveness of the core vector control measures such as insecticide-treated
bed nets and indoor residual spraying. Despite the need for strengthened research to address these problems,
there is a critical shortage in a well-trained workforce in malaria research in Myanmar. Therefore, this training
program will address key knowledge gaps in malaria research, focusing on three scientific areas. Specifically,
we aim to understand the changing malaria epidemiology in this region, to closely monitor the clinical efficacies
of antimalarial drugs and elucidate the underlying resistance mechanisms, and to determine the extent,
distribution, and mechanisms of pyrethroid resistance in major malaria vector mosquitoes. Within this training
program, mentors of diverse scientific disciplines from the University of South Florida and University of
Medicine Magway will join forces to offer multidisciplinary training in innovative approaches that address critical
problems in the current malaria elimination campaign in this region. Based on training needs assessment, we
propose to use a double-track training mechanism: 1) long-term training of three junior faculty members, three
postdoctoral fellows and six PhD students, and 2) short-term training of endemic country scientists through
annual short courses and workshops. The overall training paradigm designed in this application will ensure that
all trainees obtain the required set of technical skills and intellectual expertise to conduct independent research
on malaria. In addition, this training program will serve as an important platform for the transfer of enabling
technologies to endemic-area scientists. By advancing the careers of these trainees, this program aims to build
a critical mass of investigators and a necessary intellectual network in Myanmar to focus on malaria research.
项目摘要
东南亚大湄公河次区域(GMS)的疟疾仍然是一个重要的公共卫生问题,
问题.鉴于最近在减少与疟疾有关的发病率和死亡率方面取得的成就,
大湄公河次区域国家核可了一项区域消除疟疾计划,其最终目标是彻底消除
疟疾到2030年然而,这一雄心勃勃的计划遇到了一系列必须解决的挑战
紧急。在大湄公河次区域,疟疾在疾病分布上表现出巨大的异质性,缅甸和
占该地区确诊疟疾病例的近一半。最近出现的青蒿素
恶性疟原虫的耐药性和间日疟原虫一线治疗效果的恶化
是消灭疟疾的主要问题。此外,杀虫剂抗药性的出现,
疟疾病媒损害了核心病媒控制措施的有效性,
蚊帐和室内滞留喷洒。尽管需要加强研究来解决这些问题,
缅甸严重缺乏训练有素的疟疾研究工作人员。因此,本次培训
该计划将解决疟疾研究中的关键知识差距,重点是三个科学领域。具体地说,
我们的目标是了解该地区疟疾流行病学的变化,密切监测临床疗效,
抗疟药物的耐药性,阐明潜在的耐药机制,并确定程度,
主要疟疾病媒蚊子对拟除虫菊酯的抗药性分布和机制。在这次培训中
计划,来自南佛罗里达大学和佛罗里达大学的不同科学学科的导师。
医学马圭将联手提供创新方法的多学科培训,以解决关键的
目前该地区消灭疟疾运动中存在的问题。根据培训需求评估,我们
建议采用双轨制培养机制:1)长期培养三名初级教员,
博士后研究员和6名博士生,以及2)通过以下方式对地方病国家的科学家进行短期培训:
年度短期课程和讲习班。本应用程序中设计的整体培训模式将确保
所有受训人员都获得了进行独立研究所需的技术技能和知识专长
关于疟疾此外,这一培训方案将作为一个重要平台,
技术到地方科学家。通过推进这些学员的职业生涯,该计划旨在建立
在缅甸建立足够数量的调查人员和必要的知识网络,以专注于疟疾研究。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
LIWANG CUI其他文献
LIWANG CUI的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('LIWANG CUI', 18)}}的其他基金
Transcriptomes and Proteomes of Plasmodium Vivax
间日疟原虫的转录组和蛋白质组
- 批准号:
9241966 - 财政年份:2016
- 资助金额:
$ 24.84万 - 项目类别:
Puf-Mediated Translation Control in Plasmodium
疟原虫中 Puf 介导的翻译控制
- 批准号:
9109554 - 财政年份:2014
- 资助金额:
$ 24.84万 - 项目类别:
Puf-Mediated Translation Control in Plasmodium
疟原虫中 Puf 介导的翻译控制
- 批准号:
9314354 - 财政年份:2014
- 资助金额:
$ 24.84万 - 项目类别:
Administration of Southeast Asia Malaria Research Center
东南亚疟疾研究中心管理局
- 批准号:
8500153 - 财政年份:2013
- 资助金额:
$ 24.84万 - 项目类别:
Malaria Vector Population Genetic Division and Vector Competence in Hainan Island
海南岛疟疾媒介群体遗传划分及媒介能力
- 批准号:
8210435 - 财政年份:2012
- 资助金额:
$ 24.84万 - 项目类别:
Sex-Specific Gene Expression in Malaria Parasite Plasmodium falciparum
疟疾寄生虫恶性疟原虫的性别特异性基因表达
- 批准号:
8385372 - 财政年份:2012
- 资助金额:
$ 24.84万 - 项目类别:
Sex-Specific Gene Expression in Malaria Parasite Plasmodium falciparum
疟疾寄生虫恶性疟原虫的性别特异性基因表达
- 批准号:
8495258 - 财政年份:2012
- 资助金额:
$ 24.84万 - 项目类别:
相似海外基金
Collaborative Research: Using Adaptive Lessons to Enhance Motivation, Cognitive Engagement, And Achievement Through Equitable Classroom Preparation
协作研究:通过公平的课堂准备,利用适应性课程来增强动机、认知参与和成就
- 批准号:
2335802 - 财政年份:2024
- 资助金额:
$ 24.84万 - 项目类别:
Standard Grant
Collaborative Research: Using Adaptive Lessons to Enhance Motivation, Cognitive Engagement, And Achievement Through Equitable Classroom Preparation
协作研究:通过公平的课堂准备,利用适应性课程来增强动机、认知参与和成就
- 批准号:
2335801 - 财政年份:2024
- 资助金额:
$ 24.84万 - 项目类别:
Standard Grant
A Longitudinal Study of the Relationship between Participation in a Comprehensive Exercise Program and Academic Achievement
参加综合锻炼计划与学业成绩之间关系的纵向研究
- 批准号:
24K14615 - 财政年份:2024
- 资助金额:
$ 24.84万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Collaborative Research: Characterizing Best Practices of Instructors who Have Narrowed Performance Gaps in Undergraduate Student Achievement in Introductory STEM Courses
合作研究:缩小本科生 STEM 入门课程成绩差距的讲师的最佳实践
- 批准号:
2420369 - 财政年份:2024
- 资助金额:
$ 24.84万 - 项目类别:
Standard Grant
Collaborative Research: Using Adaptive Lessons to Enhance Motivation, Cognitive Engagement, And Achievement Through Equitable Classroom Preparation
协作研究:通过公平的课堂准备,利用适应性课程来增强动机、认知参与和成就
- 批准号:
2335800 - 财政年份:2024
- 资助金额:
$ 24.84万 - 项目类别:
Standard Grant
WTG: Diffusion of Research on Supporting Mathematics Achievement for Youth with Disabilities through Twitter Translational Visual Abstracts
WTG:通过 Twitter 翻译视觉摘要传播支持残疾青少年数学成就的研究
- 批准号:
2244734 - 财政年份:2023
- 资助金额:
$ 24.84万 - 项目类别:
Standard Grant
The Impact of Emotional Experiences of Pride on Long-Term Goal Achievement Behaviors in Elite Athletes
骄傲的情感体验对优秀运动员长期目标实现行为的影响
- 批准号:
23K16740 - 财政年份:2023
- 资助金额:
$ 24.84万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Meta-Analysis of the Instructional-Relational Model of Student Engagement and Math Achievement: A Moderation and Mediation Approach
学生参与度和数学成绩的教学关系模型的元分析:一种调节和中介方法
- 批准号:
2300738 - 财政年份:2023
- 资助金额:
$ 24.84万 - 项目类别:
Standard Grant
Improving maths achievement in children with speech, language, and communication needs through 'collaborative vocabulary teaching'
通过“协作词汇教学”提高有言语、语言和交流需求的儿童的数学成绩
- 批准号:
2890475 - 财政年份:2023
- 资助金额:
$ 24.84万 - 项目类别:
Studentship
HSI Institutional Transformation Project: Retention and Achievement for Introductory STEM English Learners (RAISE)
HSI 机构转型项目:STEM 英语入门学习者的保留和成就 (RAISE)
- 批准号:
2225178 - 财政年份:2023
- 资助金额:
$ 24.84万 - 项目类别:
Continuing Grant