Blood Research and EnhAnced Training against HIV in South Africa (BREATH-SA)

项目摘要/摘要 南部非洲地区需要协作性生物医学研究培训，以提高和装备 艾滋病毒血液系统恶性疾病的多样化而包容的科学研究团队，重点是艾滋病毒淋巴瘤 研究。开普敦大学(UCT)血液学部现有D43 Fogarty补助金 与加州大学旧金山分校共同关注艾滋病毒相关的输血医学和血液学 并正在申请这一补充机会。UCT一直在进行研究 与两个历史上处于不利地位的机构在艾滋病毒相关血液恶性肿瘤领域的合作 自由州大学(UFS)和开普敦半岛技术大学(CPUT)。那里 是非洲青年领导人接受综合和协作培训和能力培养的迫切需要 研究背景。 我们已经从三所院校中确定了六名硕士研究生和四名博士毕业生，他们都来自 代表不足的群体，他们将得到具体培训和有指导的研究的支持。建议数 该计划与家长奖的范围密切一致，将重点放在临床研究方法上 讲习班、实验室技能和方法讲习班、数据分析、数据登记处和标本储存库。 对于这项补充，我们提出了以下具体目标，以支持我们的父母赠款的目标：1) 继续建立UCT作为南非艾滋病毒血液学研究的卓越中心 通过向人类发展机构和解决研究机会中的不平等问题提供支持。2)建立三方协同 与CPUT和UFS组成的生物医学研究培训网络，以培训下一代临床研究人员 艾滋病毒血液病和淋巴瘤，将成为独立的研究人员，将解决新出现的问题 他们所服务地区的健康挑战。 这笔补充补助金将扩大科大、科大和科大之间的研究培训网络。此外，它还 为我们提供了一个机会，以培训来自人类发展机构的代表不足的科学家，并加强生物医学培训 南非的艾滋病毒血液学

PROJECT SUMMARY/ABSTRACT Collaborative biomedical research training is needed in the Southern African region to raise up and equip a diverse yet inclusive scientific research corps in HIV hematological malignancy, with focus on HIV lymphoma research. The Hematology Division at the University of Cape Town (UCT) holds an existing D43 Fogarty grant focused on HIV-related Transfusion Medicine and Hematology together with the University of California San Francisco (UCSF) and is applying for this supplement opportunity. UCT has been building research collaborations in the field of HIV-related hematological malignancy with two historically disadvantaged institutions (HDI) - the University of the Free State (UFS) and the Cape Peninsula University of Technology (CPUT). There is a critical need for young African leaders to be trained and capacitated in an integrated and collaborative research setting. We have identified six Masters students and four PhD graduates from the three institutions, all from underrepresented groups, who will be supported with specific training and mentored research. The proposed program is closely aligned with the scope of the parent award and will focus on clinical research methods workshops, laboratory skills and methods workshops, data analysis, data registries and specimen repositories. For this supplement, we propose the following specific aims which support the aims of our parent grant: 1) The continued establishment of UCT as a South African center of excellence in HIV hematology research by reaching out to HDIs and by addressing inequities in research opportunity. 2) To establish a three-way collaborative biomedical research training network with CPUT and UFS to train the next generation of clinical researchers in HIV hematological malignancies and lymphoma, to become independent researchers who will address emerging health challenges in the regions they serve. This supplement grant will expand the research training network between UCT, UFS and CPUT. Additionally, it offers an opportunity for us to train underrepresented scientists from HDIs and strengthen biomedical training in HIV hematology in South Africa