Health Outcomes in Blood Donors and Recipients

献血者和受血者的健康结果

• 批准号: 7739298
• 负责人: EDWARD L MURPHY
• 金额: $ 17.67万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-05 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7739298
• 关键词: Area; Blood Transfusion; Blood donor; Collaborations; Developed Countries; Developing Countries; Doctor of Philosophy; Epidemiologist; Faculty; Funding; Generations; Genetic; Grant; Health; Institutes; Instruction; International; Joints; Laboratories; Lead; Measures; Medicine; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Midcareer Investigator Award in Patient-Oriented Research; Outcome; Patients; Physicians; Postdoctoral Fellow; Public Health Schools; Research; Research Personnel; Research Training; SECTM1 gene; Safety; Scientist; Time; Training; Training Activity; Transfusion; Transfusion-Transmitted Virus; United States National Institutes of Health; Wages; base; career; genetic epidemiology; graduate student; improved; international center; novel; patient oriented research; programs; virus genetics

DESCRIPTION (provided by applicant): Dr. Murphy is a well-established, well-funded and productive researcher who has productively utilized the K24 mechanism during the first funding penod to leverage his participation in patient onented research (POR) and to devote substantial additional time to training and mentoring. He has been successful in traditional mentoring of graduate students, fellows and junior faculty towards their own career in POR. More novel, but still fully within the scope of the K24 award's intent, he has instituted a dynamic new program in POR training for transfusion medicine MD's and PhD's in developing countries that will lead to a new generation of researchers devoted to improving the safety and availability of blood transfusion on a woridwide basis. Finally, there are still competing demands for time and funded salary between research and training activities and remaining commitments to administrative duties. Although medium-long term mentorship has been successful, the international program is still young and the applicant would like more time for several promising trainees from the short course to transition to medium to long term mentorship. An additional five years of funding is requested to enable the formation of a Center of Excellence in POR training in international transfusion safety: Continue and expand his program of high quality POR, with a research concentration on the health outcomes of transfusion transmitted viruses and genetic epidemiology. Continue and increase medium- and long-term mentorship under the umbrella of the UCSF CTSI, UC Berkeley School of Public Health and the new roadmap K12 Masters and Ph.D. programs at UCSF. Expand and obtain independent funding for international training activities, in collaboration with the UCSF Institute for Global Health, and NIH Fogarty International Center training grants Further strengthen his own research team, promoting the independence of junior faculty and a joint (UCSF and BSRI) recruitment of a genetic epidemiologist to aid the laboratory's expansion into this new area of research. RELEVANCE (See instructions): This research training grant will support the applicant in his efforts to perform patient oriented research, and to train younger physician scientists to do this kind of research. The proposal will train graduate students, postdoctoral fellows and junior faculty in the USA and transfusion doctors in developing countries.

描述（由申请人提供）：墨菲博士是一位信誉良好、资金充足且富有成效的研究人员，他在第一次资助期间有效地利用了 K24 机制，以充分利用他对以患者为中心的研究 (POR) 的参与，并投入大量额外的时间进行培训和指导。他在对研究生、研究员和初级教师进行 POR 职业生涯的传统指导方面取得了成功。更新颖的是，但仍然完全在 K24 奖项的意图范围内，他为发展中国家的输血医学博士和博士制定了一个充满活力的 POR 培训新计划，该计划将培养新一代研究人员，致力于提高全球范围内输血的安全性和可用性。最后，研究和培训活动以及对行政职责的剩余承诺之间仍然存在对时间和资助工资的竞争需求。尽管中长期辅导取得了成功，但国际项目还很年轻，申请人希望有更多时间让几名有前途的学员从短期课程过渡到中长期辅导。需要额外五年的资金，以建立国际输血安全 POR 培训卓越中心：继续并扩大高质量 POR 计划，研究重点是输血传播病毒和遗传流行病学的健康结果。在加州大学旧金山分校 CTSI、加州大学伯克利分校公共卫生学院以及新的 K12 硕士和博士路线图的支持下，继续并增加中长期指导。加州大学旧金山分校的项目。与 UCSF 全球健康研究所和 NIH Fogarty 国际中心培训补助金合作，扩大并获得国际培训活动的独立资金。进一步加强自己的研究团队，促进初级教师的独立性，并联合（UCSF 和 BSRI）招募一名遗传流行病学家，以帮助实验室扩展到这一新的研究领域。相关性（参见说明）：这项研究培训补助金将支持申请人努力进行以患者为导向的研究，并培训年轻的医师科学家进行此类研究。该提案将培训美国的研究生、博士后研究员和初级教师以及发展中国家的输血医生。