UK NIEHS SRP Project # 3 Supplement Relating to Extending Halo-organic Capture/Remediation Technology to Corona Virus Membrane Mask and Enclosed Space Air Filter Development

英国NIEHS SRP项目

• 批准号: 10272657
• 负责人: Kelly G Pennell
• 金额: $ 27.74万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-07 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10272657
• 关键词: 2019-nCoV; Address; Adhesives; Adsorption; Aerosols; Affinity; Air; Anti-Bacterial Agents; Appearance; Area; Binding; Biochemistry; Biomedical Research; Breathing; COVID-19; Cations; Confined Spaces; Coronavirus; Data Collection; Dental crowns; Development; Drops; Electrostatics; Engineering; Environmental Pollutants; Excision; Exhibits; Exposure to; Frequencies; Gel; Generations; Glycoproteins; Goals; Health; Heating; Human; Humidity; Hydration status; Hydrogels; Hydrogen Bonding; Immobilization; Knowledge; Lead; Learning; Literature; Magnetism; Masks; Membrane; Membrane Proteins; Metals; Methods; Modification; Molecular; Morphology; Mucins; Nanostructures; National Institute of Environmental Health Sciences; Natural regeneration; Nature; Nutritional Science; Oxides; Permeability; Phase; Polymers; Property; Proteins; Public Health; Reactive Oxygen Species; Reporting; Research; Risk; Science; Signal Recognition Particle; Societies; Source; Sulfhydryl Compounds; Surface; Swelling; System; Technology; Thick; Variant; Virion; Virus; Virus Inactivation; Water; Work; aerosolized; air filter; air filtration; aqueous; base; crosslink; design; food science; graphene; hazard; iron oxide; magnetic field; materials science; monomer; nanocomposite; nanoparticle; novel; particle; physical property; pollutant; polyvinylidene fluoride; pressure; programs; regenerative; remediation; superfund site; symposium; transmission process; viral transmission

Abstract: Through our NIEHS-SRP research we have advanced materials (membranes to adsorptive and recognition-based polymers) development for degradation and capture/sensing of toxic organics from water. Membranes and polymers-based technologies are also used in air filtration area to remove particles and aerosols. Learning from nanoparticles and virus to organic separations from water media, we propose to advance the aqueous treatment technology and science to create advanced mask and enclosed space air filtration platform to capture coronavirus particles in a transformative way. By expanding on our current specific aims, the overall goal will be to bring interaction-based capture and recognition with highly efficient airborne coronavirus removal with easy breathability and air filtration properties. The transfer of smart materials development knowledge from water remediation area to airborne virus removal area will bring in immense benefit to society and human health. Virus nanoparticles (micro aerosols) build-up in enclosed air space is critical factor in viral transmission. For the enclosed space air filter, unique regenerative mechanisms will be developed. This supplement will allow us to add virus capture/deactivation functionality so that our on-going halo-organic capture/destruction technology will also be effective against coronavirus (COVID-19) environmental pollutant. Our work will involve pseudotype virus particles, and we will also concentrate on the outer surface S-protein and functionalized, synthetic nanoparticles.

翻译后摘要：通过我们的NIEHS-SRP研究，我们有先进的材料（膜吸附和 用于降解和捕获/检测水中有毒有机物的聚合物。 膜和基于聚合物的技术也用于空气过滤领域，以去除颗粒， 气溶胶从纳米粒子和病毒到水介质中的有机分离，我们建议 推进水处理技术和科学，创造先进的口罩和密闭空间空气 过滤平台，以变革性的方式捕获冠状病毒颗粒。通过扩大我们目前的具体 总体目标是将基于交互的捕获和识别与高效的机载 冠状病毒清除容易透气性和空气过滤性能。智能材料的转移 从水处理领域到空气传播病毒去除领域的发展知识将带来巨大的 有益于社会和人类健康。病毒纳米粒子（微气溶胶）在封闭的空气空间中积聚， 病毒传播的关键因素。对于封闭空间空气过滤器，将采用独特的再生机制， 开发此补充将允许我们添加病毒捕获/停用功能，以便我们正在进行的 卤代有机物捕获/销毁技术也将有效对抗冠状病毒（COVID-19） 环境污染物我们的工作将涉及假型病毒颗粒，我们也将集中在 外表面S-蛋白和功能化的合成纳米颗粒。